BibTex RIS Kaynak Göster

Drug transport to the brain

Yıl 2016, Cilt: 33 Sayı: 2, 0 - 0, 16.06.2016

S.sırrı Bilge Arzu Erdal Ağrı Bahar Akyüz

Öz

Blood brain barrier (BBB) is a special cellular system that enables the nervous system to maintain in brains homeostasis by allowing the essential materials to pass while denying harmful substances. All of the drugs with high molecular weight and 98% of the drugs with low molecular weight cannot pass through the BBB. Only a few high liposoluble molecules, which have smaller than 500 Da molecular weight, can pass through the BBB. Thus, a great number of central nervous system diseases do not respond to this kind of drugs. However, in order to effectively treat a great quantity of neurological diseases there is increasing necessity for drugs which can pass through the central nervous system. In conclusion, in recent years, studies aimed new strategies for the passage of the drugs with high molecular weight through the brain have been carried out.

Anahtar Kelimeler

Blood brain barrier brain delivery; drug transport

Yıl 2016, Cilt: 33 Sayı: 2, 0 - 0, 16.06.2016

S.sırrı Bilge Arzu Erdal Ağrı Bahar Akyüz

Öz

Toplam 0 adet kaynakça vardır.

Ayrıntılar

Bölüm Basic Medical Sciences
Yazarlar

S.sırrı Bilge

Arzu Erdal Ağrı Bu kişi benim

Bahar Akyüz

Yayımlanma Tarihi 16 Haziran 2016
Gönderilme Tarihi 30 Kasım 2015
Yayımlandığı Sayı Yıl 2016 Cilt: 33 Sayı: 2

Kaynak Göster

APA Bilge, S., Erdal Ağrı, A., & Akyüz, B. (2016). Drug transport to the brain. Journal of Experimental and Clinical Medicine, 33(2).
AMA Bilge S, Erdal Ağrı A, Akyüz B. Drug transport to the brain. J. Exp. Clin. Med. Haziran 2016;33(2).
Chicago Bilge, S.sırrı, Arzu Erdal Ağrı, ve Bahar Akyüz. “Drug Transport to the Brain”. Journal of Experimental and Clinical Medicine 33, sy. 2 (Haziran 2016).
EndNote Bilge S, Erdal Ağrı A, Akyüz B (01 Haziran 2016) Drug transport to the brain. Journal of Experimental and Clinical Medicine 33 2
IEEE S. Bilge, A. Erdal Ağrı, ve B. Akyüz, “Drug transport to the brain”, J. Exp. Clin. Med., c. 33, sy. 2, 2016.
ISNAD Bilge, S.sırrı vd. “Drug Transport to the Brain”. Journal of Experimental and Clinical Medicine 33/2 (Haziran 2016).
JAMA Bilge S, Erdal Ağrı A, Akyüz B. Drug transport to the brain. J. Exp. Clin. Med. 2016;33.
MLA Bilge, S.sırrı vd. “Drug Transport to the Brain”. Journal of Experimental and Clinical Medicine, c. 33, sy. 2, 2016.
Vancouver Bilge S, Erdal Ağrı A, Akyüz B. Drug transport to the brain. J. Exp. Clin. Med. 2016;33(2).
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