Olgu Sunumu
Yıl 2024,
Cilt: 6 Sayı: 1, 40 - 43, 01.03.2024
Öz
Ganglionöroma (GN) nöral krestten köken alan nadir görülen benign, iyi diferansiye bir neoplazidir. En sık posterior mediastende görülmekle birlikte adrenal bez de dahil olmak üzere birçok alanda izlenebilir. Posterior mediasten ve retroperiton yerleşimli lezyonlar daha çok çocuk popülasyonda, adrenal ganglionöromalar ise daha çok 4-5. dekadta izlenmektedir. Benign olmalarına rağmen çok nadir lenf nodu ve uzak organ metastazı bildirilmiştir. Bu çalışmada 3 yaşında erkek bir hastada lenf nodu metastazı gösteren, adrenal bez yerleşimli bir ganglionöroma olgusu sunulmuştur.
Anahtar Kelimeler
Kaynakça
- Iacobone M, Torresan F, Citton M, Schiavone D, Viel G, Favia G. Adrenal ganglioneuroma: The Padua Endocrine Surgery Unit experience. Int J Surg. 2017;41 Suppl 1:S103-S108. DOI: 10.1016/j.ijsu.2017.03.086.
- Ambros IM, Zellner A, Roald B, Amann G, Ladenstein R, Printz D, el al. Role of ploidy, chromosome 1p, and Schwann cells in the maturation of neuroblastoma. N Engl J Med. 1996 Jun 6;334(23):1505-11. DOI: 10.1056/NEJM199606063342304.
- Geoerger B, Hero B, Harms D, Grebe J, Scheidhauer K, Berthold F. Metabolic activity and clinical features of primary ganglioneuromas. Cancer. 2001;91(10):1905-13. DOI: 10.1002/1097-0142(20010515)91:10<1905::aid-cncr1213>3.0.co;2-4.
- Xie J, Dai J, Zhou WL, Sun FK. Adrenal Ganglioneuroma: Features and Outcomes of 42 Cases in a Chinese Population. World J Surg. 2018;42(8):2469-2475. DOI: 10.1007/s00268-018-4499-8.
- Srinivasan R, Koliyadan KS, Krishnand G, Bhat SS. Retroperitoneal ganglioneuroma with lymphnode metastasis: a case report. Indian J Pathol Microbiol. 2007;50(1):32-5.
- Hettiarachchi M, Dharmadasa C, Wijeyananda A, Hettiarachchi K, Samarasinghe B. Giant thoracic ganglioneuroma with lymph node infiltration of a child: a case report. Ann Pediatr Surg. 2020;16(1):1-4. DOI: 10.1186/s43159-020-00066-4.
- Jung HR, Kang KJ, Kwon JH, Kang YN. Adrenal ganglioneuroma with hepatic metastasis. J Korean Surg Soc. 2011 Apr;80(4):297-300. DOI: 10.4174/jkss.2011.80.4.297.
- Qing Y, Bin X, Jian W, Li G, Linhui W, Bing L, et al. Adrenal ganglioneuromas: a 10-year experience in a Chinese population. Surgery. 2010 Jun;147(6):854-60. DOI: 10.1016/j.surg.2009.11.010.
- Lebby E, Kwan D, Bui TL, O’Connell R, Seetharaman M, Houshyar R. Retroperitoneal ganglioneuroma with nodal involvement in an adult patient with human immunodeficiency virus: a case report and review of the literature. J Med Case Rep. 2021 Dec 28;15(1):634. DOI: 10.1186/s13256-021-03134-4.
- Shawa H, Elsayes KM, Javadi S, Morani A, Williams MD, Lee JE, et al. Adrenal ganglioneuroma: features and outcomes of 27 cases at a referral cancer centre. Clin Endocrinol (Oxf). 2014 Mar;80(3):342-7. DOI: 10.1111/cen.12320.
- Meng ZH, Yang YS, Cheng KL, Chen GQ, Wang LP, Li W. A huge malignant peripheral nerve sheath tumor with hepatic metastasis arising from retroperitoneal ganglioneuroma. Oncol Lett. 2013 Jan;5(1):123-126. DOI: 10.3892/ol.2012.961.
- Chandrasoma P, Shibata D, Radin R, Brown LP, Koss M. Malignant peripheral nerve sheath tumor arising in an adrenal ganglioneuroma in an adult male homosexual. Cancer. 1986;15;57(10):2022-5. DOI: 10.1002/1097-0142(19860515)57:10<2022::aid-cncr2820571023>3.0.co;2-d.
- Chen GH, He JN. Malignant ganglioneuroma of adrenals with metastasis to liver and spleen. Chin Med J (Engl). 1986 Mar;99(3):261-3.
- Salimov A, Süslü N, Kuşçu O, Süslü AE, Akyol MU, Gököz Ö, et al. Parapharyngeal giant ganglioneuroma with multifocal bone involvement in a pediatric female patient. Turk J Pediatr. 2016;58(6):669-674. DOI: 10.24953/turkjped.2016.06.016.
Yıl 2024,
Cilt: 6 Sayı: 1, 40 - 43, 01.03.2024
Öz
Ganglioneuroma (GN) is a rare benign, well-differentiated neoplasia originating from the neural crest. Although it is most commonly seen in the posterior mediastinum, it can be observed in many areas including the adrenal gland. Lesions located in the posterior mediastinum and retroperitoneum are mostly seen in the pediatric population and adrenal ganglioneuromas are more common in the 4-5. decade. GN is a benign neoplasia but very rarely lymph node and distant organ metastases have been reported. In this study, a case of adrenal gland ganglioneuroma showing lymph node metastasis in a 3-year-old male patient is presented.
Anahtar Kelimeler
Kaynakça
- Iacobone M, Torresan F, Citton M, Schiavone D, Viel G, Favia G. Adrenal ganglioneuroma: The Padua Endocrine Surgery Unit experience. Int J Surg. 2017;41 Suppl 1:S103-S108. DOI: 10.1016/j.ijsu.2017.03.086.
- Ambros IM, Zellner A, Roald B, Amann G, Ladenstein R, Printz D, el al. Role of ploidy, chromosome 1p, and Schwann cells in the maturation of neuroblastoma. N Engl J Med. 1996 Jun 6;334(23):1505-11. DOI: 10.1056/NEJM199606063342304.
- Geoerger B, Hero B, Harms D, Grebe J, Scheidhauer K, Berthold F. Metabolic activity and clinical features of primary ganglioneuromas. Cancer. 2001;91(10):1905-13. DOI: 10.1002/1097-0142(20010515)91:10<1905::aid-cncr1213>3.0.co;2-4.
- Xie J, Dai J, Zhou WL, Sun FK. Adrenal Ganglioneuroma: Features and Outcomes of 42 Cases in a Chinese Population. World J Surg. 2018;42(8):2469-2475. DOI: 10.1007/s00268-018-4499-8.
- Srinivasan R, Koliyadan KS, Krishnand G, Bhat SS. Retroperitoneal ganglioneuroma with lymphnode metastasis: a case report. Indian J Pathol Microbiol. 2007;50(1):32-5.
- Hettiarachchi M, Dharmadasa C, Wijeyananda A, Hettiarachchi K, Samarasinghe B. Giant thoracic ganglioneuroma with lymph node infiltration of a child: a case report. Ann Pediatr Surg. 2020;16(1):1-4. DOI: 10.1186/s43159-020-00066-4.
- Jung HR, Kang KJ, Kwon JH, Kang YN. Adrenal ganglioneuroma with hepatic metastasis. J Korean Surg Soc. 2011 Apr;80(4):297-300. DOI: 10.4174/jkss.2011.80.4.297.
- Qing Y, Bin X, Jian W, Li G, Linhui W, Bing L, et al. Adrenal ganglioneuromas: a 10-year experience in a Chinese population. Surgery. 2010 Jun;147(6):854-60. DOI: 10.1016/j.surg.2009.11.010.
- Lebby E, Kwan D, Bui TL, O’Connell R, Seetharaman M, Houshyar R. Retroperitoneal ganglioneuroma with nodal involvement in an adult patient with human immunodeficiency virus: a case report and review of the literature. J Med Case Rep. 2021 Dec 28;15(1):634. DOI: 10.1186/s13256-021-03134-4.
- Shawa H, Elsayes KM, Javadi S, Morani A, Williams MD, Lee JE, et al. Adrenal ganglioneuroma: features and outcomes of 27 cases at a referral cancer centre. Clin Endocrinol (Oxf). 2014 Mar;80(3):342-7. DOI: 10.1111/cen.12320.
- Meng ZH, Yang YS, Cheng KL, Chen GQ, Wang LP, Li W. A huge malignant peripheral nerve sheath tumor with hepatic metastasis arising from retroperitoneal ganglioneuroma. Oncol Lett. 2013 Jan;5(1):123-126. DOI: 10.3892/ol.2012.961.
- Chandrasoma P, Shibata D, Radin R, Brown LP, Koss M. Malignant peripheral nerve sheath tumor arising in an adrenal ganglioneuroma in an adult male homosexual. Cancer. 1986;15;57(10):2022-5. DOI: 10.1002/1097-0142(19860515)57:10<2022::aid-cncr2820571023>3.0.co;2-d.
- Chen GH, He JN. Malignant ganglioneuroma of adrenals with metastasis to liver and spleen. Chin Med J (Engl). 1986 Mar;99(3):261-3.
- Salimov A, Süslü N, Kuşçu O, Süslü AE, Akyol MU, Gököz Ö, et al. Parapharyngeal giant ganglioneuroma with multifocal bone involvement in a pediatric female patient. Turk J Pediatr. 2016;58(6):669-674. DOI: 10.24953/turkjped.2016.06.016.
Toplam 14 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Patoloji |
| Bölüm | Olgu Sunumları |
| Yazarlar | |
| Erken Görünüm Tarihi | 22 Ocak 2024 |
| Yayımlanma Tarihi | 1 Mart 2024 |
| Gönderilme Tarihi | 23 Mayıs 2023 |
| Kabul Tarihi | 18 Aralık 2023 |
| Yayımlandığı Sayı | Yıl 2024 Cilt: 6 Sayı: 1 |
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