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Rare Calcified Pseudoneoplasm of Neuraxis Presenting with Seizure in Children (CAPNON)

Yıl 2022, Cilt: 10 Sayı: 3, 131 - 133, 31.12.2022
https://doi.org/10.21765/pprjournal.1223145

Öz

Calcified pseudoneoplasms of neuraxis (CAPNON) are nonneoplastic and rare lesions of the central nervous system. Its etiology is unclear and its surgical removal is usually curative. Its radiographic features were defined by prominent calcifications seen on computed tomography (CT) and hypointensity on T1- and T2-weighted images with variable enhancement on magnetic resonance (MR) imaging. CANON, which is not common in adults, is very rare in children. The majority of reported CAPNON tumors are intracranial, although the spinal cord may also be found. It may be asymptomatic or present with headaches, seizures and focal neurological deficits when symptomatic. We present a case of a 12-year-old boy who presented with focal seizure episodes accompanied by variable consciousness and was diagnosed as CAPNON, which was rarely reported in the literature, and was followed up without surgery.

Kaynakça

  • 1- Tatke M, Singh AK, Gupta V: Calcifying pseudoneoplasm of the CNS. Br J Neurosurg 2001; 15: 521–523,
  • 2- Lyapichev K, Bregy A, Shah AH, Shah K, Desai MB, Petito C, et.al. Occipital calcified pseudoneoplasms of the neuraxis (CAPNON): understanding a rare pathology. BMJ Case Rep. 2014 Dec 5;2014:bcr2014206855.
  • 3- Stienen MN, Abdulazim A, Gautschi OP, Schneiderhan TM, Hildebrandt G, Lücke S. Calcifying pseudoneoplasms of the neuraxis (CAPNON): clinical features and therapeutic options. Acta Neurochir (Wien). 2013; 155(1): 9-17.
  • 4- Montibeller GR, Stan AC, Krauss JK, Nakamura M. Calcifying pseudoneoplasm of the inferior colliculus: an unusual location for a rare tumor: case report. Neurosurgery. 2009; 65(5): E1005-6; discussion E1006
  • 5- Bartanusz V, Ziu M, Jimenez DF, Henry JM: Calcifying pseudoneoplasm of the atlantoaxial joint in a child. J Neurosurg Spine 2013; 18 :367–371,
  • 6- Bertoni F, Unni KK, Dahlin DC, Beabout JW, Onofrio BM: Calcifying pseudoneoplasms of the neural axis. J Neurosurg 1990; 72 :42–48
  • 7- Aiken AH, Akgun H, Tihan T, Barbaro N, Glastonbury C: Calcifying pseudoneoplasms of the neuraxis: CT, MR imaging, and histologic features. AJNR Am J Neuroradiol 2009; 30: 1256–1260,
  • 8- Safaee MM, Jonzzon S, López GY, Asaikar S, Tihan T, Glenn OA, et al. Perilesional edema associated with an intracranial calcifying pseudoneoplasm of the neuraxis in a child: case report and review of imaging features. J Neurosurg Pediatr. 2018; 22(5): 528-531.

Çocuklarda Nöbet ile Prezente Olan Nadir Görülen Nöraksisin Kalsifiye Psödoneoplazmı (CAPNON)

Yıl 2022, Cilt: 10 Sayı: 3, 131 - 133, 31.12.2022
https://doi.org/10.21765/pprjournal.1223145

Öz

Nöraksisin kalsifiye psödoneoplazmaları (CAPNON), santral sinir sisteminin nonneoplastik ve nadir görülen lezyonlarıdır. Etiyolojisi belirsizdir ve cerrahi olarak çıkarılması genellikle küratiftir. Radyografik özellikleri, bilgisayarlı beyin tomografide belirgin kalsifikasyonlar ve manyetik rezonans (MR) görüntülemede değişken kontrastlanma gösteren, T1 ve T2 ağırlıklı görüntülerde hipointensite görülmesiyle tanımlanmıştır. Erişkinlerde de sık rastlanmayan CAPNON, çocuklarda ise çok nadir görülmektedir. Bildirilen CAPNON tümörlerinin büyük çoğunluğu intrakraniyal olmakla birlikte, spinal kord da bulunabilir. Asemptomatik olabildiği gibi semptom gösterdiğinde de baş ağrıları, nöbet ve fokal nörolojik defisitler ile presente olabilir. Literatürde çok nadir bildirilen, değişken bilincin eşlik ettiği fokal nöbet epizodları ile başvuran ve CAPNON tanısı alan opere olmadan takip edilen 12 yaşında çocuk olguyu sunuyoruz.

Kaynakça

  • 1- Tatke M, Singh AK, Gupta V: Calcifying pseudoneoplasm of the CNS. Br J Neurosurg 2001; 15: 521–523,
  • 2- Lyapichev K, Bregy A, Shah AH, Shah K, Desai MB, Petito C, et.al. Occipital calcified pseudoneoplasms of the neuraxis (CAPNON): understanding a rare pathology. BMJ Case Rep. 2014 Dec 5;2014:bcr2014206855.
  • 3- Stienen MN, Abdulazim A, Gautschi OP, Schneiderhan TM, Hildebrandt G, Lücke S. Calcifying pseudoneoplasms of the neuraxis (CAPNON): clinical features and therapeutic options. Acta Neurochir (Wien). 2013; 155(1): 9-17.
  • 4- Montibeller GR, Stan AC, Krauss JK, Nakamura M. Calcifying pseudoneoplasm of the inferior colliculus: an unusual location for a rare tumor: case report. Neurosurgery. 2009; 65(5): E1005-6; discussion E1006
  • 5- Bartanusz V, Ziu M, Jimenez DF, Henry JM: Calcifying pseudoneoplasm of the atlantoaxial joint in a child. J Neurosurg Spine 2013; 18 :367–371,
  • 6- Bertoni F, Unni KK, Dahlin DC, Beabout JW, Onofrio BM: Calcifying pseudoneoplasms of the neural axis. J Neurosurg 1990; 72 :42–48
  • 7- Aiken AH, Akgun H, Tihan T, Barbaro N, Glastonbury C: Calcifying pseudoneoplasms of the neuraxis: CT, MR imaging, and histologic features. AJNR Am J Neuroradiol 2009; 30: 1256–1260,
  • 8- Safaee MM, Jonzzon S, López GY, Asaikar S, Tihan T, Glenn OA, et al. Perilesional edema associated with an intracranial calcifying pseudoneoplasm of the neuraxis in a child: case report and review of imaging features. J Neurosurg Pediatr. 2018; 22(5): 528-531.
Toplam 8 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Olgu Sunusu
Yazarlar

Kübra Taşar 0000-0002-8965-2907

Abdullah Canbal 0000-0002-4048-1000

Burcu Çalışkan 0000-0001-8022-8862

Saliha Yavuz Eravcı Bu kişi benim 0000-0002-5277-5583

Cengiz Kadıyoran 0000-0002-7173-3530

Mehmet Fatih Erdi 0000-0003-3621-6658

Ahmet Güven 0000-0002-6085-1582

Erken Görünüm Tarihi 4 Eylül 2022
Yayımlanma Tarihi 31 Aralık 2022
Kabul Tarihi 30 Aralık 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 10 Sayı: 3

Kaynak Göster

Vancouver Taşar K, Canbal A, Çalışkan B, Yavuz Eravcı S, Kadıyoran C, Erdi MF, Güven A. Çocuklarda Nöbet ile Prezente Olan Nadir Görülen Nöraksisin Kalsifiye Psödoneoplazmı (CAPNON). pediatr pract res. 2022;10(3):131-3.