Öz
Aim: Widely used in many indications in dermatology practice, narrow-band ultraviolet B is a kind of ultraviolet with a wavelength usually condensing at 312nm. Our aim in this study is to introduce our 15-year experience with narrow-band UVB on 205 patients.
Materials and Methods: Gender, diagnosis, distribution of lesions, beginning dose, maximum dose, number of sessions, and cumulative dose of patients treated with narrow band UVB were retrospectively studied.
Results: The mean age of patients was 37,2 years. 44,4% of the patients was males, 55,6% was females. 34,1% of the patients were diagnosed with psoriasis and 14,6% of the patients with mycosis fungoides. 73,7% of distribution of lesions was diffused, 28% was central, and 26% was peripheral. The mean number of sessions was 27,1 and the mean cumulative dose was 21070 mJ/cm2 in the first treatment. The mean starting dose was 125,4 mJ/cm2 and the mean maximum dose was 21070 mJ/cm2.
Conclusion: Differences between the means of the number of sessions, maximum doses, cumulative doses, and diseases were statistically significant.
Key Words: Mycosis Fungoides; Narrow Band UVB; Phototherapy; Psoriasis.
Anahtar Kelimeler
Kaynakça
- Dogra S, Kanwar AJ. Narrow band UVB phototherapy in dermatology. Indian J Dermatol Venereol Leprol 2004;70(4):205-9.
- Roelandts R. The history of phototherapy: Something new under the sun? J Am Acad Dermatol 2002;46:926-30.
- Hönigsmann H. Phototherapy for psoriasis. Clin Exp Dermatol 2001;26:343-50.
- Ibbotson SH, Bilsland D, Cox NH, Dawe RS, Diffey B, Edwards C, et al. British association of dermatologists. An update and guidance on narrowband ultraviolet B phototherapy: a British photodermatology group workshop report. Br J Dermatol 2004;151(2):283-97.
- El-Ghorr AA, Norval M. Biological effects of narrow-band (311nm TL01) UVB irradiation: a review. J Photochem Photobiol 1997;38:99-106.
- Hjerppe M, Hasan T, Saksala I, Reunala T. Narrow-band UVB treatment in atopic dermatitis. Acta Derm Venereol 2001;8:439-40.
- Dawe RS. A quantitative review of studies comparing the efficacy of narrow-band and broad-band ultraviolet B for psoriasis. Br J Dermatol 2003;149:669–72.
- Molin L. Topical calcipotriol combined with phototherapy for psoriasis: the results of two randomized trials and a review of literatüre. Calcipotriol-UVB study group. Dermatology 1999;198:375-81.
- George SA, Bilsland DJ, Johnson BE, Ferguson J. Narrow-band (TL-01) UVB air-conditioned phototherapy for chronic severe adult atopic dermatitis. Br J Dermatol 1993;128:49-56.
- Pacifico A, Leone G. Photo(chemo)therapy for vitiligo. Photodermatol Photoimmunol Photomed 2011;27(5):261-77.
- Lee E, Koo J, Berger T. UVB phototherapy and skin cancer risk: a review of the literature. Int J Dermatol 2005;44:355-60.
- Friedland R, David M, Feinmesser M, Barzilai A, Hodak E. NB-UVB (311-312 nm)-induced lentigines in patients with mycosis fungoides: a new adverse effect of phototherapy. J Eur Acad Dermatol Venereol 2012;26(9):1158-62.
Öz
Amaç: Dermatoloji pratiğinde birçok endikasyonda kullanım alanı bulan dar bant ultraviyole B, dalga boyu genellikle 312nm’de yoğunlaşmış bir ultraviyole B türüdür. Bu çalışmadaki amacımız, 205 hastamızı içeren 15 yıllık dar bant UVB deneyimimizi ortaya koymaktır. Gereç ve Yöntem: Dar bant UVB tedavisi alan hastaların yaşı, cinsiyeti, tanısı, lezyonlarının yerleşim yeri, başlangıç dozu, maksimum dozu, seans sayısı ve toplamda aldığı doz retrospektif olarak değerlendirildi. Bulgular: Hastaların yaş ortalaması 37,2 yıldı. Hastaların %44,4’ü erkek, %55,6’sı kadındı. Hastaların %34,1’i psoriazis ve %14,6’sı mikozis fungoides tanısı almıştı. Lezyonların %73,7’si diffüz, %28’i santral, %26’sı ise periferik yerleşim gösteriyordu. İlk tedavi periyodundaki ortalama seans sayısı 27,1, toplam doz ortalaması ise 21070 mJ/cm2 idi. Başlangıç dozu ortalaması 125,4 mJ/cm2, maksimum doz ortalaması 1463mJ/cm2 olarak saptandı. Sonuç: Hastalıklar ile ortalama seans sayıları, maksimum doz ve toplam doz arasındaki farklar istatiksel olarak anlamlıydı
Anahtar Kelimeler
Kaynakça
- Dogra S, Kanwar AJ. Narrow band UVB phototherapy in dermatology. Indian J Dermatol Venereol Leprol 2004;70(4):205-9.
- Roelandts R. The history of phototherapy: Something new under the sun? J Am Acad Dermatol 2002;46:926-30.
- Hönigsmann H. Phototherapy for psoriasis. Clin Exp Dermatol 2001;26:343-50.
- Ibbotson SH, Bilsland D, Cox NH, Dawe RS, Diffey B, Edwards C, et al. British association of dermatologists. An update and guidance on narrowband ultraviolet B phototherapy: a British photodermatology group workshop report. Br J Dermatol 2004;151(2):283-97.
- El-Ghorr AA, Norval M. Biological effects of narrow-band (311nm TL01) UVB irradiation: a review. J Photochem Photobiol 1997;38:99-106.
- Hjerppe M, Hasan T, Saksala I, Reunala T. Narrow-band UVB treatment in atopic dermatitis. Acta Derm Venereol 2001;8:439-40.
- Dawe RS. A quantitative review of studies comparing the efficacy of narrow-band and broad-band ultraviolet B for psoriasis. Br J Dermatol 2003;149:669–72.
- Molin L. Topical calcipotriol combined with phototherapy for psoriasis: the results of two randomized trials and a review of literatüre. Calcipotriol-UVB study group. Dermatology 1999;198:375-81.
- George SA, Bilsland DJ, Johnson BE, Ferguson J. Narrow-band (TL-01) UVB air-conditioned phototherapy for chronic severe adult atopic dermatitis. Br J Dermatol 1993;128:49-56.
- Pacifico A, Leone G. Photo(chemo)therapy for vitiligo. Photodermatol Photoimmunol Photomed 2011;27(5):261-77.
- Lee E, Koo J, Berger T. UVB phototherapy and skin cancer risk: a review of the literature. Int J Dermatol 2005;44:355-60.
- Friedland R, David M, Feinmesser M, Barzilai A, Hodak E. NB-UVB (311-312 nm)-induced lentigines in patients with mycosis fungoides: a new adverse effect of phototherapy. J Eur Acad Dermatol Venereol 2012;26(9):1158-62.
Ayrıntılar
| Birincil Dil | Tr |
|---|---|
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 14 Aralık 2015 |
| Yayımlandığı Sayı | Yıl 2015 Cilt: 22 Sayı: 3 |
