Evaluation of Nebivolol Therapy in Patients with Heart Failure on Exercise Tissue Doppler Echocardiographic Parameters

Ufuk İyigün; Fatih Yalçın

doi:10.7197/cmj.1024721

EN

Evaluation of Nebivolol Therapy in Patients with Heart Failure on Exercise Tissue Doppler Echocardiographic Parameters

Abstract

Objective: Heart failure is one of the most important disease which threats population’s health. Its prevalance increases both in our country and in the world in years. Nebivolol is a molecule which is proved its efficacy in the treatment of heart failure. The aim of this study was to evaluate the changes in echocardiographic parameters such as tissue doppler imaging and myocardial performance index (MPI) after 6 months of nebivolol treatment in patients with heart failure.
Method: 20 patients with heart failure were enrolled to the study The average age was 59.8 ± 8.4 years (15 men, 5 women). During rest and exercise (cycle ergometer) we recorded conventional and tissue doppler parameters. In the first examination we recorded basal measurements. Then nebivolol treatment was administered. After 6 months nebivolol treatment we measured again same echocardiographic parameters.
Results: The average Ejection fraction (EF) of patients with heart failure in this study was %38.85 ± 6.45 in the first examination. The average EF was increased to %40.95 ± 5.47 in the end of the study (p<0.05). After 6 months nebivolol treatment both during rest and exercise we found significant improvements in the tissue doppler parameters and MPI.
Conclusions: Nebivolol is associated with significant improvements in EF in the patients with heart failure. In addition, both during rest and exercise, it’s associated with improvements in tissue doppler parameters which can show beneficial effect on the prognosis of this group of patients.

Keywords

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Ufuk İyigün ^*
0000-0002-6693-8822
Türkiye

Fatih Yalçın
0000-0002-4273-2766
Türkiye

Publication Date

March 30, 2022

Submission Date

November 22, 2021

Acceptance Date

March 20, 2022

Published in Issue

Year 2022 Volume: 44 Number: 1

DOI

https://doi.org/10.7197/cmj.1024721

IZ

https://izlik.org/JA34AC28GT

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RIS / Bibtex

AMA

1.İyigün U, Yalçın F. Evaluation of Nebivolol Therapy in Patients with Heart Failure on Exercise Tissue Doppler Echocardiographic Parameters. CMJ. 2022;44(1):31-37. doi:10.7197/cmj.1024721

Evaluation of Nebivolol Therapy in Patients with Heart Failure on Exercise Tissue Doppler Echocardiographic Parameters

Abstract

Keywords

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References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite