Are using neutrophil‐to‐lymphocyte ratio and platelet parameters useful in predicting Short Bowel Syndrome in patients with mesenteric ischemia?

Süleyman Koç; Sinan Soylu

doi:10.7197/cmj.1028980

EN

Are using neutrophil‐to‐lymphocyte ratio and platelet parameters useful in predicting Short Bowel Syndrome in patients with mesenteric ischemia?

Abstract

Objective: Acute mesenteric ischemia (AMI) is a potentially life-threatening medical condition that results in bowel infarction and gangrene. It usually occurs over the age of 60 and is seen in both sexes at similar rates. Early diagnosis and treatment are the cornerstones in the treatment of AMI. Although different biochemical markers for AMI are used clinically, no specific laboratory test has been proven to identify the presence of ischemic or necrotic bowel. In this study, we aimed to evaluate Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLT/LYM), NLR/PLT, mean platelet volume-PLT ratio (MPV)/PLT, and MPV*NLR/PLT could be a useful tool for early prediction of the severity of AMI.

Method: We analyzed retrospectively records of 105 patients diagnosed with acute AMI who were operated on at our clinic. We investigated patient demographics, clinical symptoms, concomitant diseases, blood test results, and data regarding the surgical procedure performed and the resection's width. The patients were divided into two groups as short bowel syndrome (SBS) developing and non-developing.

Results: We enrolled a total of 105 AMI patients in this study. There was no significant difference between the rates of non-SBS and SBS in terms of age, gender, diabetes mellitus, and smoking status. WBC, NEU, LYM, and MPV were higher, and PLT was lower in the SBS group. There were no statistically significant differences in MPV/PLT between the two groups. The combined values of NLR, PLT, and MPV were also compared between non-SBS and SBS groups. According to our results, the means of NLR, PLT/LYM, NLR/PLT, MPV/NLR, and MPV*NLR/PLT variables were statistically significantly different between the two groups.

Conclusions: Our findings showed that NLR, NLR/PLT, MPV/PLT, MPV*NLR, and MPV*NLR/PLT could be a relatively better tool for early prediction of the severity of AMI and SBS. Further studies have to be carried out to investigate the best parameter for predicting the severity or prognosis of AMI.

Keywords

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Süleyman Koç
0000-0001-7794-4518
Türkiye

Sinan Soylu ^*
0000-0002-3911-3227
Türkiye

Publication Date

December 31, 2021

Submission Date

November 26, 2021

Acceptance Date

November 30, 2021

Published in Issue

Year 2021 Volume: 43 Number: 4

DOI

https://doi.org/10.7197/cmj.1028980

IZ

https://izlik.org/JA62BP32JG

Cite

RIS / Bibtex

AMA

1.Koç S, Soylu S. Are using neutrophil‐to‐lymphocyte ratio and platelet parameters useful in predicting Short Bowel Syndrome in patients with mesenteric ischemia? CMJ. 2021;43(4):413-419. doi:10.7197/cmj.1028980

Are using neutrophil‐to‐lymphocyte ratio and platelet parameters useful in predicting Short Bowel Syndrome in patients with mesenteric ischemia?

Abstract

Keywords

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References

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Journal Section

Authors

Publication Date

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Acceptance Date

Published in Issue

DOI

IZ

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