EN
Comparison of amylase, lipase and d-dimer levels in the etiopathogenesis of mortality in Covid 19 pneumonia
Abstract
Objective: Coronavirus Disease 2019 (Covid-19) is a pandemic cause affecting the whole world with high mortality. The effects of lipase, amylase and d-dimer levels on mortality were investigated in Covid-19 pneumonia in the present study.
Method: A total of 131 patients diagnosed with pneumonia due to Covid-19 and 60 healthy control groups were included in the study prospectively. The cases were divided into 3 groups as the healthy control group, those who recovered, and those who died. Those who had pneumonia in the lung tomography among the cases diagnosed with Covid-19 were examined. The RT-PCR (Real-Time Polymerized Chain Reaction) test results were recorded from the system. The serum lipase, amylase, albumin levels, WBC (White Blood Cell), N/L (Neutrophil/Lymphocyte Ratio), and CRP (C-Reactive Protein) levels of the patients were compared with those of the Control Group.
Results: When all the data were reviewed, the Lipase, Amylase, and d-dimer levels were found to be statistically significantly higher in the exitus group when compared to the control group, and T. protein and albumin levels were lower (p<0.01). Other acute phase reactants, WBC, N/L Ratio, and CRP levels were significantly higher (p<0.01). As a result of the comparison of the recovered and exitus group, no statistically significant changes were detected in all parameters (p>0.05).
Conclusions: The elevation in serum amylase, lipase, and d-dimer levels may be significant in prognosis in pneumonia developing due to Covid-19.
Method: A total of 131 patients diagnosed with pneumonia due to Covid-19 and 60 healthy control groups were included in the study prospectively. The cases were divided into 3 groups as the healthy control group, those who recovered, and those who died. Those who had pneumonia in the lung tomography among the cases diagnosed with Covid-19 were examined. The RT-PCR (Real-Time Polymerized Chain Reaction) test results were recorded from the system. The serum lipase, amylase, albumin levels, WBC (White Blood Cell), N/L (Neutrophil/Lymphocyte Ratio), and CRP (C-Reactive Protein) levels of the patients were compared with those of the Control Group.
Results: When all the data were reviewed, the Lipase, Amylase, and d-dimer levels were found to be statistically significantly higher in the exitus group when compared to the control group, and T. protein and albumin levels were lower (p<0.01). Other acute phase reactants, WBC, N/L Ratio, and CRP levels were significantly higher (p<0.01). As a result of the comparison of the recovered and exitus group, no statistically significant changes were detected in all parameters (p>0.05).
Conclusions: The elevation in serum amylase, lipase, and d-dimer levels may be significant in prognosis in pneumonia developing due to Covid-19.
Keywords
References
- Referans1 RR, Simadibrata M. Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID-19) patients: Is it really pancreatic injury? JGH Open. 2020 Dec 28;5(2):190-192. doi: 10.1002/jgh3.12436.
Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Publication Date
March 30, 2022
Submission Date
January 4, 2022
Acceptance Date
March 29, 2022
Published in Issue
Year 2022 Volume: 44 Number: 1
AMA
1.Ercan Haydar F, Otal Y, Avcıoğlu G. Comparison of amylase, lipase and d-dimer levels in the etiopathogenesis of mortality in Covid 19 pneumonia. CMJ. 2022;44(1):117-124. doi:10.7197/cmj.1053522