Thyroid Nodule Prevalence in Non-Alcoholic Fatty Liver

Zeynep Ergenç; Hasan Ergenç; Özlem Karaca Ocak; Feyzi Gökosmanoğlu

doi:10.7197/cmj.1088088

EN

Thyroid Nodule Prevalence in Non-Alcoholic Fatty Liver

Abstract

Objectives: This study aimed to investigate the effects of non-alcoholic fatty liver disease on thyroid nodule prevalence Methods: A total of 384 patients who were followed up with Grade 2-3 Non-Alcoholic Fatty Liver diagnosis were investigated for the presence of multinodular and/or nodular goiter. Demographic characteristics, biochemical data, and abdominal and thyroid ultrasonography reports of the patients were collected from patient files and electronic records. Results: The ALT (cut-off level 10-40 U/L), GGT (cut-level 0 - 65 U / L), triglyceride (0-150 mg/dL), homeostasis model assessment of insulin resistance (HOMA-IR index value < 2.71), and TSH (cut-off level 0.45-4.12 mU / L), which are biochemical and metabolic parameters examined in our study, increased at statistically significant levels as the fat increased in the liver. A total of 45.8% (176/384) of the patients had Grade-2 Non-Alcoholic Fatty Liver Disease, and 54.1% (208/384) had Grade-3 Non-Alcoholic Fatty Liver Disease. As fat increased in the Non-Alcoholic Fatty Liver Disease, the prevalence of nodules increased at statistically significant levels (p=0.001). Conclusion: Our study found that the frequency of thyroid nodules, disruption of the parenchymal structure, and metabolic and biochemical disruption are parallel in non-Alcoholic fatty liver patients.

Keywords

Supporting Institution

None

Project Number

None

Thanks

N/A

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Zeynep Ergenç
Türkiye

Hasan Ergenç ^*
0000-0003-0519-0264
Türkiye

Özlem Karaca Ocak
0000-0003-3637-4074
Türkiye

Feyzi Gökosmanoğlu
0000-0002-6432-8668
Türkiye

Publication Date

December 31, 2022

Submission Date

March 18, 2022

Acceptance Date

December 29, 2022

Published in Issue

Year 2022 Volume: 44 Number: 4

DOI

https://doi.org/10.7197/cmj.1088088

IZ

https://izlik.org/JA23CK86BC

Cite

RIS / Bibtex

AMA

1.Ergenç Z, Ergenç H, Karaca Ocak Ö, Gökosmanoğlu F. Thyroid Nodule Prevalence in Non-Alcoholic Fatty Liver. CMJ. 2022;44(4):412-415. doi:10.7197/cmj.1088088