Case Report

A unique case of malignant pleural mesothelioma presenting with highly aggressive multiple brain metastases after a long disease-free period

Volume: 39 Number: 3 September 19, 2017
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A unique case of malignant pleural mesothelioma presenting with highly aggressive multiple brain metastases after a long disease-free period

Abstract

Malignant pleural mesothelioma (MPM) is an uncommon, aggressive malignant neoplasm derived from the mesothelial cells of pleura or peritoneum characterized by poor outcome. Mesothelioma is thought to metastasize locally only via direct invasion and not have distant spread. Distant metastases are discovered mostly on post-mortem examination. However, recent post-mortem studies have identified metastases to the central nervous system (CNS) in about 3% of cases. A 55 year old patient presented with agressive multiple brain metastases after 4 years from the initial diagnosis. Palliative cranial radiotherapy was given because of unresectability of the lesions. The patient died 3 months after completion of radiotherapy. Distant metastase patern is not predictable in this disease, thus attention should be paid on the high-risk factors at initial presentation to prevent systemic relapses. Multimodality therapies have been produced longer survival times in this disease; clinicians should perform careful screening for brain metastasis in MPM, especially in patients with risk factors including younger age, advanced stage and non-epithelioid features.

Keywords

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Case Report

Authors

Furkan Bertug Cetin

Erkan Kayikcioglu

Banu Ozturk

Mustafa Yildiz

Publication Date

September 19, 2017

Submission Date

December 11, 2016

Acceptance Date

May 27, 2017

Published in Issue

Year 2017 Volume: 39 Number: 3

DOI

https://doi.org/10.7197/223.v39i31705.347463

IZ

https://izlik.org/JA25BW99UK

Cite

RIS / Bibtex
APA
Aydın, A. A., Bertug Cetin, F., Kayikcioglu, E., Ozturk, B., & Yildiz, M. (2017). A unique case of malignant pleural mesothelioma presenting with highly aggressive multiple brain metastases after a long disease-free period. Cumhuriyet Medical Journal, 39(3), 624-628. https://doi.org/10.7197/223.v39i31705.347463
AMA
1.Aydın AA, Bertug Cetin F, Kayikcioglu E, Ozturk B, Yildiz M. A unique case of malignant pleural mesothelioma presenting with highly aggressive multiple brain metastases after a long disease-free period. CMJ. 2017;39(3):624-628. doi:10.7197/223.v39i31705.347463
Chicago
Aydın, Asim Armagan, Furkan Bertug Cetin, Erkan Kayikcioglu, Banu Ozturk, and Mustafa Yildiz. 2017. “A Unique Case of Malignant Pleural Mesothelioma Presenting With Highly Aggressive Multiple Brain Metastases After a Long Disease-Free Period”. Cumhuriyet Medical Journal 39 (3): 624-28. https://doi.org/10.7197/223.v39i31705.347463.
EndNote
Aydın AA, Bertug Cetin F, Kayikcioglu E, Ozturk B, Yildiz M (September 1, 2017) A unique case of malignant pleural mesothelioma presenting with highly aggressive multiple brain metastases after a long disease-free period. Cumhuriyet Medical Journal 39 3 624–628.
IEEE
[1]A. A. Aydın, F. Bertug Cetin, E. Kayikcioglu, B. Ozturk, and M. Yildiz, “A unique case of malignant pleural mesothelioma presenting with highly aggressive multiple brain metastases after a long disease-free period”, CMJ, vol. 39, no. 3, pp. 624–628, Sept. 2017, doi: 10.7197/223.v39i31705.347463.
ISNAD
Aydın, Asim Armagan - Bertug Cetin, Furkan - Kayikcioglu, Erkan - Ozturk, Banu - Yildiz, Mustafa. “A Unique Case of Malignant Pleural Mesothelioma Presenting With Highly Aggressive Multiple Brain Metastases After a Long Disease-Free Period”. Cumhuriyet Medical Journal 39/3 (September 1, 2017): 624-628. https://doi.org/10.7197/223.v39i31705.347463.
JAMA
1.Aydın AA, Bertug Cetin F, Kayikcioglu E, Ozturk B, Yildiz M. A unique case of malignant pleural mesothelioma presenting with highly aggressive multiple brain metastases after a long disease-free period. CMJ. 2017;39:624–628.
MLA
Aydın, Asim Armagan, et al. “A Unique Case of Malignant Pleural Mesothelioma Presenting With Highly Aggressive Multiple Brain Metastases After a Long Disease-Free Period”. Cumhuriyet Medical Journal, vol. 39, no. 3, Sept. 2017, pp. 624-8, doi:10.7197/223.v39i31705.347463.
Vancouver
1.Asim Armagan Aydın, Furkan Bertug Cetin, Erkan Kayikcioglu, Banu Ozturk, Mustafa Yildiz. A unique case of malignant pleural mesothelioma presenting with highly aggressive multiple brain metastases after a long disease-free period. CMJ. 2017 Sep. 1;39(3):624-8. doi:10.7197/223.v39i31705.347463