Assessment of tumor lysis syndrome cases
Abstract
Objective: Tumor lysis syndrome (TLS) is a clinical picture that occurs with the rapid destruction of tumor cells and with life-threatening metabolic disorders. The aim of our study is to evaluate the etiologic causes, diagnosis and treatment of TLS cases.
Method: The study was conducted between January 2015 and December 2017 in Kahramanmaras Necip Fazıl city Hospital. [HT1] A total of 32 patients diagnosed with TLS were included in the study. Laboratory values of patients were scanned (blood urea nitrogen, creatinine, potassium, phosphorus, calcium, serum uric acid, lactate dehydrogenase) and diagnoses, chemotherapy and treatments were noted.
Results: Of the 32 patients who were included in the study, 17 were male and 15 were female. The average age of the patients was found as 62,06 ± 12,10 (35-86) years. Hematologic malignancy was detected in the etiology of 11 of the TLS cases and solid tumor was detected in 21 of the TLS cases. A total of 12 (37.5%) patients had spontaneous TLS (5 in haematological malignancy and 7 in solid tumor). Hyperpotassaemia 50%, hypocalcaemia 46.9%, hyperphosphatemia, hyperuricemia and acute kidney damage was present in all patients. Mortality rate was found as 40.6%.
Conclusions: In our study, spontaneous TLS was detected at a high rate. In addition, the mortality rate was also high. Early diagnosis and urgent treatment should be planned to avoid mortalities.
Keywords
References
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Authors
Can Hüzmeli
*
Türkiye
Publication Date
March 28, 2019
Submission Date
September 16, 2018
Acceptance Date
March 20, 2019
Published in Issue
Year 1970 Volume: 41 Number: 1
Cited By
Tümör Lizis Sendromunda Hemşirelik Yaklaşımı
Ordu Üniversitesi Hemşirelik Çalışmaları Dergisi
https://doi.org/10.38108/ouhcd.782461