The impact of mean platelet volume on post-dural puncture headaches
Abstract
Objective: Post-dural puncture headache (PDPH) is a major complication associated with loss of cerebrospinal fluid (CSF), which occurs due to dural defect. Platelets play an important role in tissue healing and homeostasis. Mean platelet volume (MPV) is an indication of platelet function. In this study we wanted to investigate the relationship between MPV and PDPH.
Method: Between January 2016 and January 2018, 182 patients who had a caesarean using spinal anaesthesia were included in this study. Patients were divided into two groups as PDPH (+) and PDPH (-). The preoperative and postoperative haemoglobin (HGB), haematocrit (HCT), platelet (PLT), MPV, white blood cell (WBC), neutrophil (NEUT) and lymphocyte (LYMPH) levels of the patients according to PDPH were evaluated.
Results: There was no difference between preoperative and postoperative MPV values of PDPH (+) patients (respectively 10.77±1.17, 10.83±1.04, p=0.483) but there was a significant difference between MPV values of PDPH (-) patients (respectively 10.94±1.20, 11.10±1.11, p<0.001).
Conclusions: There are a number of reasons that affect and predict the occurrence of PDPH. According to this study, postoperative MPV levels (high or low) could cause a prediction for PDPH.
Keywords
References
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Authors
Hakan Tapar
*
0000-0001-7625-0864
Türkiye
Publication Date
March 28, 2019
Submission Date
January 17, 2019
Acceptance Date
March 27, 2019
Published in Issue
Year 2019 Volume: 41 Number: 1