Pulmonary alveolar microlithiasis: quantitative approach by bone scintigraphy
Abstract
Abstract
Pulmonary alveolar microlithiasis (PAM) is a rare idiopathic disease of unknown etiology and pathogenesis. PAM is characterized histopathologically by extensive intra-alveolar calcium and phosphate deposition throughout both lung parenchymas. None-invasive diagnosis of pulmonary calcification and ossification requires various imaging techniques, including chest radiography and computed tomography, while bone scintigraphy may play a role in the disease staging by quantitative analysis. In this report, we presented a quantitative assessment technique for calcified foci in lungs by means of relative density analysis in successive bone scintigraphies of a patient with PAM.
Keywords: Pulmonary alveolar microlithiasis, bone scintigraphy, density, computed tomography.
Özet
Pulmoner alveolar mikrolitiyazis (PAM) etiyoloji ve patogenezi bilinmeyen nadir idiopatik bir hastalıktır. Histopatolojik olarak her iki akciğer parankiminde yaygın intra-alveolar kalsiyum ve fosfat çökmesi ile karakterizedir. Pulmoner kalsifikasyon ve ossifkasyonun non-invaziv tanısı direkt akciğer grafisi, bilgisayarlı tomografi gibi görüntüleme tekniklerini gerektirirken, kemik sintigrafisi de kantitatif analiz ile hastalığın düzeyi hakkında bilgi vererek rol alabilir. Bu raporda, bir PAM hastasının bir birini takip eden kemik sintigrafilerinde rölatif dansite analizi ile akciğerlerdeki kalsifiye odakların kantitatif olarak değerlendirildiği bir yöntem sunuldu.
Anahtar sözcükler: Pulmoner alveolar mikrolitiyasis, kemik sintigrafisi, dansite, bilgisayarlı tomografi
Keywords
References
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Details
Primary Language
English
Subjects
-
Journal Section
-
Authors
Taner Erselcan
Serdar Gül
Zekiye Hasbek
Hulusi Eğilmez
Cesur Gümüş
Publication Date
October 27, 2009
Submission Date
October 27, 2009
Acceptance Date
-
Published in Issue
Year 2009 Volume: 31 Number: 4