Relationship between coronary artery calcification and various biomarkers in type 2 diabetic patients

Alpaslan Karabulut; Serhat İçağasıoğlu; Fettah Acıbucu; Fatih Kılıçlı; Cesur Gümüş; Osman Yontar

EN TR

Relationship between coronary artery calcification and various biomarkers in type 2 diabetic patients

Abstract

Abstract

Aim. Cardiovascular disease is the most common made of mortality in type 2 diabetes mellitus. This study investigated the relationship between the presence of calcification in coronary artery and biochemical parameters alone with the classic risk factors of atherosclerosis in patients with type 2 diabetes. Methods. Forty one (27 female and 14 male) patients with type 2 diabetes without symptomatic coronary artery disease (CAD) or previous myocardial infarction and with normal kidney functions were included in the study. Multislice Computerized Tomography (MSCT) was used for coronary artery calcium scoring (CACS). Patients were classifed into two groups as CACS=0 and CACS>0. Results. In 12 (29.3%) patients coronary artery calcification was noted. Waist circumference, systolic blood pressure, total cholesterol, low-density lipoprotein, and triglyceride levels were significantly different between those with (CACS>0) and without (CACS=0) (p<0.05). Conclusion. Coronary artery calcification is related to atherosclerosis in diabetic patients.

Keywords: Type 2 diabetes mellitus, atherosclerosis, coronary artery calcification

Özet

Amaç. Kardiyovasküler hastalık Tip 2 Diabetes Mellitus’ta mortalitenin en sık görülen nedenidir. Bu çalışmada Tip 2 diyabetik hastalarda, koroner arterdeki kalsifikasyon varlığı ile biyokimyasal parametreler ve aterosklerozun klasik risk faktörleri arasındaki ilişki incelendi Yöntemler. Çalışmaya, semptomatik koroner arter hastalığı (KAH) yada geçirilmiş miyokard infarktüsü olmayan ve böbrek fonksiyonları normal olan, 41 (27 kadın, 14 erkek) Tip 2 diyabetik hasta alındı. Çok Kesitli Bilgisayarlı Tomografi (ÇKBT) ile koroner arter kalsiyum skorlaması (KAKS) yapıldı. Hastalar KAKS=0 ve KAKS>0 olarak 2 gruba ayrıldı. Bulgular. 12 (%29,3) hastada koroner arterlerde kalsifikasyon saptandı. Bel çevresi, sistolik kan basıncı, total kolesterol, düşük dansiteli lipoprotein ve trigliserid seviyeleri ile KAKS arasındaki ilişki önemli bulundu (p<0,05). Sonuç. Diyabetik hastalarda koroner arter kalsifikasyonu aterosklerozla ilişkilidir.

Anahtar sözcükler: Tip 2 diabetes mellitus, ateroskleroz, koroner arter kalsifikasyonu

Keywords

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References

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Details

Primary Language

English

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-

Journal Section

-

Authors

Osman Yontar

Publication Date

March 27, 2012

Submission Date

June 22, 2011

Acceptance Date

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Published in Issue

Year 2012 Volume: 34 Number: 1

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https://izlik.org/JA25BR92MB

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RIS / Bibtex

AMA

1.Karabulut A, İçağasıoğlu S, Acıbucu F, Kılıçlı F, Gümüş C, Yontar O. Relationship between coronary artery calcification and various biomarkers in type 2 diabetic patients. CMJ. 2012;34(1):48-55. https://izlik.org/JA25BR92MB

Relationship between coronary artery calcification and various biomarkers in type 2 diabetic patients

Relationship between coronary artery calcification and various biomarkers in type 2 diabetic patients

Abstract

Keywords

Original research-Orijinal araştırma

Öz

Anahtar Kelimeler

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

IZ

Cite