Multipl primer malign neoplaziler: Cumhuriyet Üniversitesi verileri

Nalan Akgül Babacan; Saadettin Kılıçkap; Şafak Şahin; Birsen Yücel; Turgut Kaçan; Ebru Atasever Akkaş; Yıllar Lehimcioğlu Okur; Mehmet Fuat Eren

TR

Multipl primer malign neoplaziler: Cumhuriyet Üniversitesi verileri

Öz

Amaç. Onkolojik tedavilerdeki gelişmeler ve beklenen yaşam süresinin uzaması, tedavilerin geç yan etkileri ve ikinci kanserlerin gelişimi gibi sorunları da beraberinde getirmiştir. Aynı kişide, patolojik olarak tanımlanmış birden fazla malign tümörün varlığı multipl primer malign neoplazi (MPMN) olarak tanımlanmaktadır. Biz bu çalışmayla merkezimizde MPMN tanısı almış hastalarımızın demografik, patolojik ve klinik özelliklerini incelemeyi amaçladık. Yöntem. Merkezimize Ocak 2007 ile Ocak 2012 tarihleri arasında başvuran toplam 3108 kanser hastasına ait dosya bilgileri retrospektif olarak tarandı. Bulgular. Merkezimizde takip edilen 3108 kanser hastasının 38’i (%1,2) MPMN tanısı almış idi. Bunların 21’i (%55,3) kadın, 17’si (%44,7) erkekti. Otuz yedi hastada iki primer neoplazi saptanırken, 1 hastada 3 primer neoplazi saptandı. Hastaların ortanca ikinci tümör tanı yaşı 60 (32-76) bulundu. Hastaların 6’sı (%15,8) senkron, 32’si (%84,2) metakron olarak MPMN tanısı almıştı. İki tanı arası geçen ortanca süre 40 aydı (0-372 ay). Hastalardaki en sık ilk primer tümör jinekolojik tümörler (10 hasta, %26,3) iken, en sık ikinci primer tümör meme kanseri (7 hasta, %18,4) idi. En sık tümör birliktelikleri ise sırasıyla: jinekolojik tümörler-meme kanseri (5 hasta, %13,1), jinekolojik-jinekolojik tümörler (3 hasta, %7,9), sarkom-meme kanseri (3 hasta, %7,9), baş boyun tümörleri-akciğer kanseri (3 hasta, %7,9), üriner sistem-üriner sistem tümörleri (3 hasta, %7,9) şeklindeydi. Sonuçlar. Sonuçlarımız literatürr ile uyumludur. Kanser tanısı almış hastalar, olası ikinci kanserler, koruyucu önlemler ve tarama hakkında bilgilendirilmeli ve şüpheli lezyonlarda biyopsiden kaçınılmamalıdır.

Anahtar Kelimeler

Kanser, ikinci primer neoplasm, multipl neoplaziler, metakron, senkron

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Details

Primary Language

Turkish

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-

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-

Authors

Şafak Şahin

Yıllar Lehimcioğlu Okur

Mehmet Fuat Eren

Publication Date

March 1, 2012

Submission Date

March 1, 2012

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-

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Year 2012 Volume: 34 Number: 4

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https://izlik.org/JA94RM49NW

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RIS / Bibtex

AMA

1.Akgül Babacan N, Kılıçkap S, Şahin Ş, et al. Multipl primer malign neoplaziler: Cumhuriyet Üniversitesi verileri. CMJ. 2012;34(4):405-410. https://izlik.org/JA94RM49NW

Abstract

Multipl primer malign neoplaziler: Cumhuriyet Üniversitesi verileri

Öz

Anahtar Kelimeler

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

IZ

Cite