Benign recurrent intrahepatic cholestasis associated with pregnancy
Abstract
Abstract
Benign recurrent intrahepatic cholestasis is a rare condition which is believed to be an autosomal recessive disorder characterized by mutation in the aminophospholipid flippase gene ATP8B1 located on chromosome 18q21. It is characterized by recurrent episodes of intrahepatic cholestasis with normal gamma glutamyl transferase. We here describe a case of benign intrahepatic cholestasis associated with pregnancy.
Keywords: Benign recurrent intrahepatic cholestasis, jaundice, pregnancy
Özet
Benign rekürren inrahepatik kolestaz nadir bir durum olup 18q21 kromozomu üzerindeki aminofosfolipid flippaz geni ATP8B1’de oluşan mutasyona ikincil gelişen otozomal resesif bir hastalık olduğu düşünülmektedir. Gamma glutamil transferaz enziminin normal olduğu rekürren intrahepatik kolestaz epizotları ile karakterizedir.Burada gebelikle ilişkili bir benign intrahepatik kolestaz olgusu anlatılmıştır.
Anahtar sözcükler: Benign rekürren intrahepatik kolestaz, sarılık, gebelik
Keywords
Details
Primary Language
English
Subjects
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Journal Section
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Publication Date
April 23, 2012
Submission Date
April 23, 2012
Acceptance Date
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Published in Issue
Year 2012 Volume: 34 Number: 4