Comparison of clinicopathologic features of young and older patients with sporadic colorectal adenocarcinoma
Abstract
Abstract
Aim. There is still considerable controversy and debate regarding the features of colorectal cancer in young and older patients. In the present study, the influence of age on clinicopathological characteristics of sporadic colorectal cancer is analyzed retrospectively. Method. A total of 170 cases of colectomy for adenocarcinoma in Kocaeli University Medical School, Turkey, Department of Surgery between January 2001 and September 2005 were studied. Results. Of the 170 patients, 40 (23.5%) were in the ≤50 age group and 130 (76.5%) in the >50 age group were included in the study. Statistical tests were applied for the variables. No differences were found between the young and older patients in respect of clinical features, histopathological features, surgical procedures, or post-operative complications. Conclusion. According to this study, there are no differences between young and older patients with sporadic colorectal adenocarcinoma in respect of clinical features, histopathological features, surgical procedures, or post-operative complications. The differences found previously as recorded in the literature may be associated with genetic variations.
Keywords: Colorectal, adenocarcinoma, sporadic
Özet
Amaç. Yaşlı ve genç yaş hastalarda kolorektal kanserlerin özellikleriyle ilgili halen süregelen tartışmalar vardır. Bu çalışmada yaşın sporadik kolorektal kanserlerin klinikopatolojik karakteristikleri üzerine etkisi retrospektif olarak incelendi. Yöntem. Ocak 2001-Eylül 2005 arasında adenokarsinom nedeniyle Kocaeli Üniversitesi Tıp Fakültesi Genel Cerrahi Kliniği’nde kolektomi yapılan toplam 170 olgu retrospektif olarak incelendi. Bulgular. Yüz yetmiş olgudan 40’ı (%23,5) elli yaş ve altında, 130’u (%76,5) elli yaşın üstünde idi. Elde edilen sonuçlar istatistiksel olarak değerlendirildi. Yaşlı ve genç hasta grupları arasında klinik özellkler, histopatolojik özellikler, uygulanan cerrahi yöntemler veya ameliyat sonrası komplikasyonlar açısından fark bulunmadı. Sonuç. Bu çalışmaya gore sporadik kolerektal adenokarsinomlu genç ve yaşlı hastalar arasında kilnik özellikler, histopatolojik özellikler, uygulanan cerrahi yöntemler veya ameliyat sonrası komplikasyonlar açısından fark yoktur. Literatürlerde belirtilen daha once saptanmış olan farklar gentetik varyasyonlarla ilişkili olabilir.
Anahtar sözcükler: Kolorektal, adenokarsinom, sporadik
Keywords
References
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Details
Primary Language
English
Subjects
-
Journal Section
-
Authors
Emel Gönüllü
Çağrı Tiryaki
Recai Çapoğlu
Murat Yazıcıoğlu
Mustafa Haksal
Ahmet Alponat
Publication Date
March 28, 2014
Submission Date
August 16, 2013
Acceptance Date
-
Published in Issue
Year 2014 Volume: 36 Number: 1
Cited By
Our colonoscopic polypectomy experience in the tertiary hospital endoscopy unit
Journal of Biotechnology and Strategic Health Research
https://doi.org/10.34084/bshr.1205030