Evaluation of platelet indices in acute, subacute and, chronic phases of deep venous thrombosis

Fatih Ada; Vural Polat

doi:10.7197/cmj.vi.610865

EN TR

Evaluation of platelet indices in acute, subacute and, chronic phases of deep venous thrombosis

Abstract

Objective: The etiology of deep vein thrombosis disease is multifactorial, and currently it is seen as a public health problem. Simple, cheap and useful tests that can be used for diagnosis, treatment, and follow-up is increasingly needed day by day because of increasing number of patients. For this purpose, the changes of platelet indices in routine hemogram tests during DVT follow-up were examined retrospectively.

Method: This study is a retrospective analysis of patients who diagnosed with deep venous thrombosis in Sivas Cumhuriyet University School of Medicine between 01.01.2017-31.12.2018 years. The investigation started after the decision of Sivas Cumhuriyet University Local Ethics Committee No. 2019-02/67. The acute, subacute and chronic phase parameters of patients with deep venous thrombosis were evaluated. The study included 72 patients who developed DVT. Platelet indexes and other hemogram parameters were analyzed statistically according to the phases of deep vein thrombosis.

Results: 55.6% of the patients were female, and 44.4% were male. DVT was found most commonly in the left femoral region (48.6%). PDW and MPV tended to increase rapidly in the acute phase of deep vein thrombosis and managed to fall in the subacute and chronic phases. However, there was no statistically significant change in platelet count and platelet crit.

Conclusions: PDW and MPV appear to be useful markers in the follow-up of all stages of deep vein thrombosis. It is evident that with the developing technology, more sensitive and specific parameters of platelet indices will be obtained.

Keywords

Derin venöz trombozun akut, subakut ve kronik fazlarında platelet indekslerinin değerlendirilmesi

Öz

Amaç: Derin ven trombozu etiyolojisi multifaktöriyel bir hastalık olup günümüzde bir halk sağlığı problemi olarak görülmektedir. Artan hasta sayısıyla birlikte tanı, tedavi ve takipte kullanılabilecek basit, ucuz ve kullanışlı testlere ihtiyaç her geçen gün artmaktadır. Bu amaçla rutin hemogram testlerinde yer alan platelet indekslerinin DVT takibinde ki değişimleri retrospektif olarak incelenmiştir. Yöntem: Bu çalışma, 01.01.2017-31.12.2018 tarihleri arasında Sivas Cumhuriyet Üniversitesi Tıp Fakültesinde, tanı konulmuş derin venöz trombozlu hastaların retrospektif bir analizidir. Çalışmaya, Sivas Cumhuriyet Üniversitesi Yerel Etik Kurulunun 2019-02/67sayılı kararı sonrası başlandı. Derin venöz trombozlu hastaların akut, subakut ve kronik faz parametreleri değerlendirildi. Çalışmaya DVT gelişen 72 hasta dâhil edildi. Trombosit indeksleri ve diğer hemogram parametreleri derin ven trombozunun evrelerine göre istatistiksel olarak analiz edildi. Bulgular: DVT görülen hastaların %55,6’sı kadın ve %44,4’ü erkek idi. En sık sol femoral bölgede (%48,6) DVT saptanmıştır. PDW ve MPV,derin venöz trombozun akut fazında hızlı bir yükselişe geçerken subakut ve kronik fazlarda düşme eğiliminde idi. Bununla birlikte platelet sayısı ve plateletkritin istatistiksel olarak anlamlı bir değişimi yoktu. Sonuç: Derin ven trombozun tüm evrelerinin takibinde PDW ve MPV iyi birer marker olarak görünmektedir. Gelişen teknoloji ile birlikte platelet indekslerine ait çok daha hassas ve özgül parametrelerin elde edileceği de aşikârdır.

Anahtar Kelimeler

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Fatih Ada ^*
0000-0002-6953-5906
Türkiye

Vural Polat
0000-0001-9553-3990
Türkiye

Publication Date

September 30, 2019

Submission Date

August 26, 2019

Acceptance Date

September 28, 2019

Published in Issue

Year 2019 Volume: 41 Number: 3

DOI

https://doi.org/10.7197/cmj.vi.610865

IZ

https://izlik.org/JA36SH58YZ

Cite

RIS / Bibtex

AMA

1.Ada F, Polat V. Evaluation of platelet indices in acute, subacute and, chronic phases of deep venous thrombosis. CMJ. 2019;41(3):544-550. doi:10.7197/cmj.vi.610865

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