Research Article

Different polymicrogyria patterns and associated anomalies in childhood: MRI findings

Volume: 41 Number: 3 September 30, 2019
EN

Different polymicrogyria patterns and associated anomalies in childhood: MRI findings

Abstract

Polymicrogyria is a developmental anomaly which has been diagnosed in recent years due to improvements in neuroimaging methods. It may present with very different clinical findings. It can be seen in many different patterns. It can be found with different nervous system anomalies. In this article, different polymicrogyria patterns and associated anomalies detected in childhood are presented with MRI findings.

Keywords

References

  1. 1. Leventer RJ, Guerrini R, Dobyns WB. Malformations of cortical development and epilepsy. Dialogues. Clin Neurosci. 2008; 10: 47-62.
  2. 2. Golden JA, Harding BN. Cortical malformations: unfolding polymicrogyria. Nat Rev Neurol. 2010; 6: 471-72.
  3. 3. Barkovich AJ, Gressens P, Evrard P. Formation, maturation, and disorders of brain neocortex. AJNR Am J Neuroradiol 1992; 13: 423–46.
  4. 4. Evrard P, de Saint-Georges P, Kadhim HJ, Gadisseux JF. Pathology of prenatal encephalopathies. In: French J (ed) Child neurology and developmental disabilities. Paul H. Brookes, Baltimore, 1989, pp 153–76
  5. 5. Englund C, Fink A, Lau C et al. Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. J Neurosci 2005; 25: 247–51
  6. 6. Dobyns WB, Mirzaa G, Christian SL, Petras K, Roseberry J, Clark GD, et al. Consistent chromosome abnormalities identify novel polymicrogyria loci in 1p36.3, 2p16.1-p23.1, 4q21.21-q22.1, 6q26-q27, and21q2. Am J Med Genet A 2008; 146: 1637–54
  7. 7. Robin NH, Taylor CJ, Donald-McGinn DM, Zackai EH, Bingham P,Collins KJ, et al. Polymicrogyria and deletion 22q11.2 syndrome: window to the etiology of a common cortical malformation. Am J Med Genet. 2006; 140: 2416–25.
  8. 8. Barkovich AJ, Kuzniecky RI, Jackson GD, Guerrini R, Dobyns WB. Classification system for malformations of cortical development: update 2001. Neurology 2001; 57: 2168–78.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Mehmet Atalar

Bülent Yıldız

İsmail Şalk

Publication Date

September 30, 2019

Submission Date

August 31, 2019

Acceptance Date

September 2, 2019

Published in Issue

Year 1970 Volume: 41 Number: 3

AMA
1.Başpınar N, Atalar M, Yıldız B, Şalk İ. Different polymicrogyria patterns and associated anomalies in childhood: MRI findings. CMJ. 2019;41(3):531-536. doi:10.7197/223.vi.613523