Research Article

Ocular parameters quantified by the swept-source optical coherence tomography in celiac disease

Volume: 42 Number: 3 October 27, 2020
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Cumhuriyet Medical Journal
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Ocular parameters quantified by the swept-source optical coherence tomography in celiac disease

Abstract

Objective: To measure anterior and posterior segmental ocular parameters in patients with celiac disease using swept-source optical coherence tomography and compare with those of healthy subjects. 
Method: Fourteen patients with celiac disease referred from the gastroenterology clinic and 14 control subjects selected from the individuals with minor complaints who admitted the ophthalmology outpatient clinic were included in the study. Mean and segmental retinal nerve fiber layer thickness in four quadrant, average and sectoral ganglion cell inner plexiform layer thickness in six quadrant, foveal and parafoveal vessel density in four quadrant, optic nerve head parameters, including rim area, disc area, horizontal cup-to-disc ratio, vertical cup-to-disc ratio, cup volume, and additionally superficial/deep foveal avascular zone areas, choroidal thickness, and central corneal thickness of patients and controls were quantified using swept-source optical coherence tomography.
Results: Among all the measurements, retinal nerve fiber layer in nasal quadrant and subfoveal choroid of patients were significantly thicker than those of controls. Nasal quadrant retinal nerve fiber layer thickness for patients and controls were 91.62±15.27 µm and 79.93±10.43 µm, respectively (P=0.02). Choroidal thickness was 377.69±50.77 µm for patients and 310.93±95.13 µm for controls (P=0.03).
Conclusions: Even though celiac disease is primarily a disease of small intestine, this study demonstrated that the disorder can affect the eye as an extra intestinal involvement.

Keywords

Supporting Institution

Yok

Project Number

Yok

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Publication Date

October 27, 2020

Submission Date

August 14, 2020

Acceptance Date

September 21, 2020

Published in Issue

Year 2020 Volume: 42 Number: 3

DOI

https://doi.org/10.7197/cmj.vi.780554

IZ

https://izlik.org/JA83CB56AT

Cite

RIS / Bibtex
AMA
1.Yener AÜ, Akpınar MY, Kahramanoğlu E, Sapmaz F, Nazlıgul Y. Ocular parameters quantified by the swept-source optical coherence tomography in celiac disease. CMJ. 2020;42(3):327-333. doi:10.7197/cmj.vi.780554