Evaluation of retinal nerve fiber layer thickness and macular thickness in amblyopic children

Damla Culha; Mustafa Arıcı

doi:10.7197/cmj.821209

EN

Evaluation of retinal nerve fiber layer thickness and macular thickness in amblyopic children

Abstract

Objective: To compare central macular and retinal nerve fiber layer (RNFL) thickness using Spectral Domain Optical Coherence Tomography (SD-OCT) among patients with hyperopic anisometropic, strabismic and mixed amblyopia and healthy controls.

Method: This prospective, cross-sectional study included 39 amblyopic children, their fellow eyes and 20 healthy individuals. Central macular and RNFL (superior, nasal, inferior and temporal quadrants and mean RNFL) thicknesses were measured with SD-OCT.

Results: Difference was not statistically significant in the central macular thickness when the anisometropic, strabismic and mixed amblyopia groups were compared among themselves, fellow eyes and healthy control group.

In the anisometropic amblyopic group, the inferior RNFL and nasal RNFL values were significantly thicker compared to the fellow eyes (p=0.009, p=0.028, respectively). Mean RNFL measurements were significantly thicker in anisometropic and mixed groups in the amblyopic eyes compared to the fellow eyes (p=0.009, p=0.031, respectively). In the temporal quadrant, the RNFL was found to be statistically significantly thinner in the anisometropic and mixed amblyopic groups compared to the fellow eyes (p=0.049, p=0.010, respectively).

Conclusions: There was no considerably difference in the central macular thickness among the amblyopia groups, fellow eyes and healthy controls. However, significant changes were found in the mean RNFL and certain quadrants of the RNFL thicknesses in the anisometropic and mixed amblyopic groups.

Keywords

Supporting Institution

Cumhuriyet University (Scientific Research Project)

Project Number

T-621

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Damla Culha ^*
0000-0002-0678-135X
Türkiye

Mustafa Arıcı
0000-0002-6350-9723
Türkiye

Publication Date

September 30, 2021

Submission Date

November 9, 2020

Acceptance Date

September 30, 2021

Published in Issue

Year 2021 Volume: 43 Number: 3

DOI

https://doi.org/10.7197/cmj.821209

IZ

https://izlik.org/JA92HN88TF

Cite

RIS / Bibtex

APA

Culha, D., & Arıcı, M. (2021). Evaluation of retinal nerve fiber layer thickness and macular thickness in amblyopic children. Cumhuriyet Medical Journal, 43(3), 232-240. https://doi.org/10.7197/cmj.821209

AMA

1.Culha D, Arıcı M. Evaluation of retinal nerve fiber layer thickness and macular thickness in amblyopic children. CMJ. 2021;43(3):232-240. doi:10.7197/cmj.821209

Chicago

Culha, Damla, and Mustafa Arıcı. 2021. “Evaluation of Retinal Nerve Fiber Layer Thickness and Macular Thickness in Amblyopic Children”. Cumhuriyet Medical Journal 43 (3): 232-40. https://doi.org/10.7197/cmj.821209.

EndNote

Culha D, Arıcı M (September 1, 2021) Evaluation of retinal nerve fiber layer thickness and macular thickness in amblyopic children. Cumhuriyet Medical Journal 43 3 232–240.

IEEE

[1]D. Culha and M. Arıcı, “Evaluation of retinal nerve fiber layer thickness and macular thickness in amblyopic children”, CMJ, vol. 43, no. 3, pp. 232–240, Sept. 2021, doi: 10.7197/cmj.821209.

ISNAD

Culha, Damla - Arıcı, Mustafa. “Evaluation of Retinal Nerve Fiber Layer Thickness and Macular Thickness in Amblyopic Children”. Cumhuriyet Medical Journal 43/3 (September 1, 2021): 232-240. https://doi.org/10.7197/cmj.821209.

JAMA

1.Culha D, Arıcı M. Evaluation of retinal nerve fiber layer thickness and macular thickness in amblyopic children. CMJ. 2021;43:232–240.

MLA

Culha, Damla, and Mustafa Arıcı. “Evaluation of Retinal Nerve Fiber Layer Thickness and Macular Thickness in Amblyopic Children”. Cumhuriyet Medical Journal, vol. 43, no. 3, Sept. 2021, pp. 232-40, doi:10.7197/cmj.821209.

Vancouver

1.Damla Culha, Mustafa Arıcı. Evaluation of retinal nerve fiber layer thickness and macular thickness in amblyopic children. CMJ. 2021 Sep. 1;43(3):232-40. doi:10.7197/cmj.821209