Research Article
Year 2019,
, 295 - 300, 30.06.2019
Abstract
References
- 1. Zapolski T, Wysoki Ski A, Ksi Ek A, Jaroszy Ski A. Left atrial volume index and aortic stiffness index in adult hemodialysed patients - link between compliance and pressure mediated by endothelium dysfunction; a cross-sectional study. BMC Cardiovasc Disord 2012; 12: 100.
- 2. Laurent S, Boutouyrie P, Ama R, et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 2001; 37: 1236-41.
- 3. Hsu SR, Su HM, Hsieh MC, et al. Risk factors of accelerated progression of peripheral artery disease in hemodialysis. Kaohsiung J Med Sci 2013; 29: 82-7.
- 4. Unlu M, Demirkol S, Aparci M, et al. Why aortic elasticity differs among classical and non-classical mitral valve prolapsed? Clin Exp Hypertens 2014; 36: 148-52.
- 5. Yazici M, Ataoglu S, Makarc S, et al. The relationship between echocardiographic features of mitral valve and elastic properties of aortic wall and Beighton hypermobility score in patients with mitral valve prolapse. Jpn Heart J 2004; 45: 447-60.
- 6. Kardesoglu E, Ozmen N, Aparci M, et al. Abnormal elastic properties of the aorta in the mitral valve prolapse syndrome. Acta Cardiol 2007; 62: 151-5.
- 7. Boutouyrie P, Fliser D, Goldsmith D, et al. Assessment of arterial stiffness for clinical and epidemiological studies: methodological considerations for validation and entry into the European Renal and Cardiovascular Medicine registry. Nephrol Dial Transplant 2014; 29: 232-9.
- 8. Liu CS, Li CI, Shih CM, et al. Arterial stiffness measured as pulse wave velocity is highly correlated with coronary atherosclerosis in asymptomatic patients. J Atheroscler Thromb 2011; 18: 652-8.
- 9. Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol 2010; 55: 1318-27.
- 10. Hu Y, Li L, Shen L, Gao H. The relationship between arterial wall stiffness and left ventricular dysfunction. Neth Heart J 2013; 21: 222-27.
- 11. Pereira T, Maldonado J, Pereira L, Conde J. Aortic stiffness is an independent predictor of stroke in hypertensive patients. Arq Bras Cardiol 2013; 100: 437-43.
- 12. Karras A, Haymann JP, Bozec E, et al. Large artery stiffening and remodeling are independently associated with all-cause mortality and cardiovascular events in chronic kidney disease. Hypertension 2012; 60: 1451-7.
- 13. Mohty D, Pibarot P, Echahidi N, et al. Reduced systemic arterial compliance measured by routine Doppler echocardiography: a new and independent predictor of mortality in patients with type 2 diabetes mellitus. Atherosclerosis 2012; 225: 353-8.
- 14. Uçar Elalmış O, Ciçekçioğlu H, Karagöz A, Ozbalkan Aşlar Z, Karaaslan Y. Evaluation of aortic elastic properties in patients with systemic sclerosis. Turk Kardiyol Dern Ars 2014; 42: 635-42.
- 15. Santos MJ, Carmona-Fernandes D, Canhão H, et al. Early vascular alterations in SLE and RA patients--a step towards understanding the associated cardiovascular risk. PLoS One 2012; 7: e44668.
- 16. Balcı H, Demirkök SS, Yıldız M, et al. The relationship between inflammatory markers and arteriel distensibility in patients with sarcoidosis. Balkan Med J 2010; 27: 44-50
- 17. Schmeisser A, Flachskampf FA. [Mitral valve prolapse]. Z Kardiol 2000; 89: 349-53.
- 18. Moyssakis I, Gialafos E, Vassiliou V, et al. Aortic stiffness in systemic sclerosis is increased independently of the extent of skin involvement. Rheumatology 2005; 44: 251-4.
Year 2019,
, 295 - 300, 30.06.2019
Abstract
Objective: Mitral valve
prolapse (MVP) is one of the most frequently seen cardiac disorders. The basic
pathophysiologic mechanism is deterioration in the connective tissue leading to
increased elasticity of mitral leaflets. Elasticity of the aorta which is a
well established predictor of adverse cardiovascular outcomes may also differ
in these patients when alteration in the connective tissue is taken into
account. The aim of this study is to investigate the elastic properties of the
aorta in patients with MVP.
Method: Thirty seven patients with MVP and 38 healthy controls were evaluated in
terms of aortic elastic properties using aortic strain, aortic stiffness index
and aortic distensibility.
Results: Median value for aortic strain was 0.07 (0.0338-0.231) in MVP group and
0.079 (0.0345-0.28) in the control group (p=0.359). Aortic stiffness was
calculated on the basis of aortic strain. The mean value for stiffness index
was 6.87 ± 3.59 and 6.21 ± 2.83 in the MVP and control groups respectively
(p=0.388). Distensibility of the aorta was quantified with a median value of
3286 (1229-12700) in patients with MVP and 3400 (1087-13790) in healthy
subjects (p=0.346). Eventually, when the aortic elastic parameters were
compared (aortic strain, stiffness index and distensibility), no difference was
found between MVP and control groups.
Conclusions: The elastic properties of the aorta do not differ in patients with MVP
when compared to healthy individuals. It will not be accurate to predict long
term cardiovascular outcomes based on elastic properties of the aorta in
patients with MVP.
References
- 1. Zapolski T, Wysoki Ski A, Ksi Ek A, Jaroszy Ski A. Left atrial volume index and aortic stiffness index in adult hemodialysed patients - link between compliance and pressure mediated by endothelium dysfunction; a cross-sectional study. BMC Cardiovasc Disord 2012; 12: 100.
- 2. Laurent S, Boutouyrie P, Ama R, et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 2001; 37: 1236-41.
- 3. Hsu SR, Su HM, Hsieh MC, et al. Risk factors of accelerated progression of peripheral artery disease in hemodialysis. Kaohsiung J Med Sci 2013; 29: 82-7.
- 4. Unlu M, Demirkol S, Aparci M, et al. Why aortic elasticity differs among classical and non-classical mitral valve prolapsed? Clin Exp Hypertens 2014; 36: 148-52.
- 5. Yazici M, Ataoglu S, Makarc S, et al. The relationship between echocardiographic features of mitral valve and elastic properties of aortic wall and Beighton hypermobility score in patients with mitral valve prolapse. Jpn Heart J 2004; 45: 447-60.
- 6. Kardesoglu E, Ozmen N, Aparci M, et al. Abnormal elastic properties of the aorta in the mitral valve prolapse syndrome. Acta Cardiol 2007; 62: 151-5.
- 7. Boutouyrie P, Fliser D, Goldsmith D, et al. Assessment of arterial stiffness for clinical and epidemiological studies: methodological considerations for validation and entry into the European Renal and Cardiovascular Medicine registry. Nephrol Dial Transplant 2014; 29: 232-9.
- 8. Liu CS, Li CI, Shih CM, et al. Arterial stiffness measured as pulse wave velocity is highly correlated with coronary atherosclerosis in asymptomatic patients. J Atheroscler Thromb 2011; 18: 652-8.
- 9. Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol 2010; 55: 1318-27.
- 10. Hu Y, Li L, Shen L, Gao H. The relationship between arterial wall stiffness and left ventricular dysfunction. Neth Heart J 2013; 21: 222-27.
- 11. Pereira T, Maldonado J, Pereira L, Conde J. Aortic stiffness is an independent predictor of stroke in hypertensive patients. Arq Bras Cardiol 2013; 100: 437-43.
- 12. Karras A, Haymann JP, Bozec E, et al. Large artery stiffening and remodeling are independently associated with all-cause mortality and cardiovascular events in chronic kidney disease. Hypertension 2012; 60: 1451-7.
- 13. Mohty D, Pibarot P, Echahidi N, et al. Reduced systemic arterial compliance measured by routine Doppler echocardiography: a new and independent predictor of mortality in patients with type 2 diabetes mellitus. Atherosclerosis 2012; 225: 353-8.
- 14. Uçar Elalmış O, Ciçekçioğlu H, Karagöz A, Ozbalkan Aşlar Z, Karaaslan Y. Evaluation of aortic elastic properties in patients with systemic sclerosis. Turk Kardiyol Dern Ars 2014; 42: 635-42.
- 15. Santos MJ, Carmona-Fernandes D, Canhão H, et al. Early vascular alterations in SLE and RA patients--a step towards understanding the associated cardiovascular risk. PLoS One 2012; 7: e44668.
- 16. Balcı H, Demirkök SS, Yıldız M, et al. The relationship between inflammatory markers and arteriel distensibility in patients with sarcoidosis. Balkan Med J 2010; 27: 44-50
- 17. Schmeisser A, Flachskampf FA. [Mitral valve prolapse]. Z Kardiol 2000; 89: 349-53.
- 18. Moyssakis I, Gialafos E, Vassiliou V, et al. Aortic stiffness in systemic sclerosis is increased independently of the extent of skin involvement. Rheumatology 2005; 44: 251-4.
There are 18 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Medical Science Research Articles |
| Authors | |
| Publication Date | June 30, 2019 |
| Acceptance Date | May 7, 2019 |
| Published in Issue | Year 2019 |