Research Article
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Year 2019, , 747 - 753, 31.12.2019
https://doi.org/10.7197/cmj.vi.633752

Abstract

References

  • References1. Cotzias CS, Paterson-Brown S, Fisk NM. Obstetricians say yes to maternal request for elective caesarean section: a survey of current opinion. Eur J Obstet Gynaecol Reprod Biol 2001; 97: 15-6.2. Hansen T, Corbet A. Disorders of the transition. In: Taeusch HW, Ballard RA (eds): Avery’s diseases of newborn. 7 th edition. Philadelphia: WB Saunders Company;1998. 613-5.3. Ovalı F. Yenidoğanın geçici taşipnesi. Dağoğlu T (ed). Neonatoloji. İstanbul: Nobel Tıp Kitabevi; 2000. 297-8.4. Tricia Lacy Gomella. Respiratory Distres Syndrome. Neonatology 1999; 503-4.5. Morrison JJ, Rennie JM, Milton PJ. Neonatal respiratory morbidity and mode of delivery at term: influence of timing of elective caesarean section. Br J Obstet Gynaecol 1995;102:101-6.6. Schatz M, Zeiger RS, Hoffman CP, Saunders BS, Harden KM, Forsythe AB. Increased transient tachypnoea of the newborn in infants of asthmatic mothers. Am J Dis Child 1991;145:156-8.7. Demissie K, Marcella SW, Breckenridge MB, Rhoads GG. Maternal asthma and transient tachypnoea of the newborn. Pediatrics 1998; 102: 84-90. 10 Crowley P. Prophylactic corticosteriods for preterm birth. Cochrane Database Syst Rev 2000;(2):CD000065.8. Robert ME, Neff RK, Hubbell JP, Taeusch HW, Avery ME. Association between maternal diabetes and the respiratory distress syndrome in the newborn. N Engl J Med 1976; 294: 357- 60.9. Royal College of Obstetricians and Gynaecologists Scientific Advisory Committee. RCOG guidelines No 7: antenatal corticosteroids to prevent respiratory distress syndrome. 2nd ed. London: RCOG Press, 2004:1-9.10. Crowley P, Chalmers I, Keirse MJNC. The effects of corticosteroid administration before preterm delivery: an overview of the evidence from controlled trials. Br J Obstet Gynaecol 1990; 97: 11- 25.11. Stutchfield P, Whitaker R, Russell I, Antenatal Steroids for Term Elective Caesarean Section (ASTECS) Research Team. Antenatal betamethasone and incidence of neonatal respiratory distress after elective caesarean section: pragmatic randomised trial. BMJ 2005; 331(7518): 662.12. Creasy RK, Iams JD. Preterm labor and delivery. In: Creasy RK, Resnik R (eds). Maternal Fetal Medicine (4th ed). Philadelphia: WB Saunders, 2000: 498-509.13. Collaborative group on antenatal steroid therapy. Effect of antenatal dexamethasone administration on the prevention of respiratory distress syndrome. Am J Obstet Gynecol 1981; 141: 276-87.14. NIH Consensus Development Conference Statement. Effect of corticosteroids for fetal maturation on perinatal outcomes. JAMA 1995; 273: 413-18.15. Cosmi EV, Anceschi MM. Prevention of fetal and neonatal lung immaturity. In: Textbook of Perinatal Medicine (1st ed). Carnforth: The Parthenon Publishing Group Ltd, 1998: 1382-92.16. Lagrew DC Jr, Morgan MA. Decreasing the cesarean section rate in a private hospital : success without mandated clinical changes . Am J Obstet Gynecol 1996; 174: 184-9117. Kay HH, Bird IM. Kay HH, Bird IM, Coe CL, Dudley DJ. Antenatal steroid treatment and adverse fetal effects: what is the evidence? J Soc Gynecol Investig 2000; 7: 269-78.18. NIH Consensus Development Conference Statement. Effect of corticosteroids for fetal maturation on perinatal outcomes. JAMA 1995; 273: 413-18.19. Morales WJ, Diebel ND, Lazar AJ, Zadrozny D. The effect of antenatal dexamethasone administration on the gestations with premature rupture of membranes. Am J Obstet Gynecol 1986; 154: 591-95.20. Gamsu HR, Mullinger BM, Donnai P, Dash CH. Antenatal administration of betamethasone to prevent respiratory distress syndrome in preterm infants: report of a UK multicentre trial. Br J Obstet Gynaecol 1989; 96: 401-10.21. Ahmed MR, Ahmed WAS, Mohammed TY. Antenatal steroids at 37 weeks, does it reduce neonatal respiratory morbidity? A randomized trial. Journal of Maternal-Fetal & Neonatal Medicine 2015;28(12):1486–90.22. Nada AM, Shafeek MM, El Maraghy MA, Nageeb AH, Salaheldine AS, Awad MH. Antenatal corticosteroid administration before elective caesarean section et term to prevent neonatal respiratory morbidity: a randomized controlled trial. European Journal of Obstetrics, Gynecology, and Reproductive Biology 2016; 199: 88–91.23. Nooh AM, Abdeldayem HM, Arafa E, Shazly SA, Elsayed H, Mokhtar WA. Does implementing a regime of dexamethasone before planned cesarean section at term reduce admission with respiratory morbidity to neonatal intensive care unit? A randomized controlled trial. Journal of Maternal-Fetal & Neonatal Medicine 2018; 31(5): 614–20.

Antenatal betamethasone administration before elective caesarean section in term pregnant women

Year 2019, , 747 - 753, 31.12.2019
https://doi.org/10.7197/cmj.vi.633752

Abstract

Objective: The aim of this
study is to show that respiratory problems such as respiratory distressed
syndrome and transient tachypnea of newborn can be reduced by antenatal
betamethasone administration.

Method: The study
was conducted on 50 mothers and their babies aged between 21 and 38 years in
the Obstetrics and Gynecology Clinic of Haydarpaşa Numune Training and Research
Hospital between January 2007 and March 2008.
Betamethasone was
administered to 25 patients who were planned for cesarean section at term due
to elective reasons (Group I). The Group II consisted of 25 patients planned
for elective caesarean section at term and no betamethasone was administered.
Groups were compared according to maternal age, maternal smoking, maternal
chronic disease history, gestation day, cesarean section type of anesthesia,
birth weight and sex of the baby. Postnatal infants were evaluated according to Apgar
scores of 1 and 5 minutes, ventilation with mask, intubation, resuscitation or
intensive care needs. RDS and TNT were recorded.

Results: In the
non-corticosteroid-treated group (group 2), two babies developed TNT of the
newborn. However, no statistically significant difference was found between the
groups (p> 0.05). Respiratory distress syndrome did not develop in any of
our patients. The abortion rate in Group I (20%) was significantly higher than
the abortion rate in Group II (0%) (p <0.05).
No other parameters (Age, gravida, parity, number of
curettage, number of living children, smoking,presence of chronic disease,
anesthesia type) were statistically significant (p>0.05).







Conclusions: The use of antenatal corticosteroid in elective
caesarean sections over 37 weeks may cause a decrease in the development of
respiratory problems such as RDS and YGT.

References

  • References1. Cotzias CS, Paterson-Brown S, Fisk NM. Obstetricians say yes to maternal request for elective caesarean section: a survey of current opinion. Eur J Obstet Gynaecol Reprod Biol 2001; 97: 15-6.2. Hansen T, Corbet A. Disorders of the transition. In: Taeusch HW, Ballard RA (eds): Avery’s diseases of newborn. 7 th edition. Philadelphia: WB Saunders Company;1998. 613-5.3. Ovalı F. Yenidoğanın geçici taşipnesi. Dağoğlu T (ed). Neonatoloji. İstanbul: Nobel Tıp Kitabevi; 2000. 297-8.4. Tricia Lacy Gomella. Respiratory Distres Syndrome. Neonatology 1999; 503-4.5. Morrison JJ, Rennie JM, Milton PJ. Neonatal respiratory morbidity and mode of delivery at term: influence of timing of elective caesarean section. Br J Obstet Gynaecol 1995;102:101-6.6. Schatz M, Zeiger RS, Hoffman CP, Saunders BS, Harden KM, Forsythe AB. Increased transient tachypnoea of the newborn in infants of asthmatic mothers. Am J Dis Child 1991;145:156-8.7. Demissie K, Marcella SW, Breckenridge MB, Rhoads GG. Maternal asthma and transient tachypnoea of the newborn. Pediatrics 1998; 102: 84-90. 10 Crowley P. Prophylactic corticosteriods for preterm birth. Cochrane Database Syst Rev 2000;(2):CD000065.8. Robert ME, Neff RK, Hubbell JP, Taeusch HW, Avery ME. Association between maternal diabetes and the respiratory distress syndrome in the newborn. N Engl J Med 1976; 294: 357- 60.9. Royal College of Obstetricians and Gynaecologists Scientific Advisory Committee. RCOG guidelines No 7: antenatal corticosteroids to prevent respiratory distress syndrome. 2nd ed. London: RCOG Press, 2004:1-9.10. Crowley P, Chalmers I, Keirse MJNC. The effects of corticosteroid administration before preterm delivery: an overview of the evidence from controlled trials. Br J Obstet Gynaecol 1990; 97: 11- 25.11. Stutchfield P, Whitaker R, Russell I, Antenatal Steroids for Term Elective Caesarean Section (ASTECS) Research Team. Antenatal betamethasone and incidence of neonatal respiratory distress after elective caesarean section: pragmatic randomised trial. BMJ 2005; 331(7518): 662.12. Creasy RK, Iams JD. Preterm labor and delivery. In: Creasy RK, Resnik R (eds). Maternal Fetal Medicine (4th ed). Philadelphia: WB Saunders, 2000: 498-509.13. Collaborative group on antenatal steroid therapy. Effect of antenatal dexamethasone administration on the prevention of respiratory distress syndrome. Am J Obstet Gynecol 1981; 141: 276-87.14. NIH Consensus Development Conference Statement. Effect of corticosteroids for fetal maturation on perinatal outcomes. JAMA 1995; 273: 413-18.15. Cosmi EV, Anceschi MM. Prevention of fetal and neonatal lung immaturity. In: Textbook of Perinatal Medicine (1st ed). Carnforth: The Parthenon Publishing Group Ltd, 1998: 1382-92.16. Lagrew DC Jr, Morgan MA. Decreasing the cesarean section rate in a private hospital : success without mandated clinical changes . Am J Obstet Gynecol 1996; 174: 184-9117. Kay HH, Bird IM. Kay HH, Bird IM, Coe CL, Dudley DJ. Antenatal steroid treatment and adverse fetal effects: what is the evidence? J Soc Gynecol Investig 2000; 7: 269-78.18. NIH Consensus Development Conference Statement. Effect of corticosteroids for fetal maturation on perinatal outcomes. JAMA 1995; 273: 413-18.19. Morales WJ, Diebel ND, Lazar AJ, Zadrozny D. The effect of antenatal dexamethasone administration on the gestations with premature rupture of membranes. Am J Obstet Gynecol 1986; 154: 591-95.20. Gamsu HR, Mullinger BM, Donnai P, Dash CH. Antenatal administration of betamethasone to prevent respiratory distress syndrome in preterm infants: report of a UK multicentre trial. Br J Obstet Gynaecol 1989; 96: 401-10.21. Ahmed MR, Ahmed WAS, Mohammed TY. Antenatal steroids at 37 weeks, does it reduce neonatal respiratory morbidity? A randomized trial. Journal of Maternal-Fetal & Neonatal Medicine 2015;28(12):1486–90.22. Nada AM, Shafeek MM, El Maraghy MA, Nageeb AH, Salaheldine AS, Awad MH. Antenatal corticosteroid administration before elective caesarean section et term to prevent neonatal respiratory morbidity: a randomized controlled trial. European Journal of Obstetrics, Gynecology, and Reproductive Biology 2016; 199: 88–91.23. Nooh AM, Abdeldayem HM, Arafa E, Shazly SA, Elsayed H, Mokhtar WA. Does implementing a regime of dexamethasone before planned cesarean section at term reduce admission with respiratory morbidity to neonatal intensive care unit? A randomized controlled trial. Journal of Maternal-Fetal & Neonatal Medicine 2018; 31(5): 614–20.
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Details

Primary Language English
Subjects Health Care Administration
Journal Section Surgical Science Research Articles
Authors

Begum Kurt 0000-0002-7166-3130

Gültekin Kose 0000-0002-7894-8809

Publication Date December 31, 2019
Acceptance Date December 31, 2019
Published in Issue Year 2019

Cite

AMA Kurt B, Kose G. Antenatal betamethasone administration before elective caesarean section in term pregnant women. CMJ. December 2019;41(4):747-753. doi:10.7197/cmj.vi.633752