Research Article
Year 2020,
, 359 - 365, 27.10.2020
Abstract
References
- 1. Perez MI, Kohn SR. Cutaneous manifestations of diabetes mellitus. J Am Acad Dermatol 1995; 32(4): 143-144.
- 2. Bouguerra R, Essais O, Sebai N, Ben Salem L, Amari H, Kammoun MR,et all. Prevalence and clinical aspects of superficial mycosis in hospitalized diabetic patients in Tunisia. Med Mal Infect 2004; 34(5): 201-205.
- 3. Tan JS, Joseph WS. Common fungal infections of the feet in patients with diabetes mellitus. Drugs Aging 2004; 21(2): 101-112.
- 4. Somolinos AL, Sànchez JL. Prevalence of dermatophytosis in patients with diabetes. J Am Acad Dermatol 1992; 26: 408-410.
- 5. Dogra S, Kumar B, Bhansali A, Chakrabarty A. Epidemiology of onychomycosis in patients with diabetes mellitus in India. International Journal of Dermatology 2002; 41: 647-651.
- 6. Aşçı Z, Seyrek A, Kizirgil A, Yılmaz M. Diyabetli hastalarda tinea unguium araştırılması. Turkish Journal of Infection 1996; 10(4): 365-367.
- 7. Oz Y,Oz A, Qoaraan I, Balta I. Prevalence and epidemiology of tinea pedis and toenail onychomycosis and antifungal susceptibility of the causative agents in patients with type 2 diabetes in Turkey Int J Dermatol. 2017 Jan;56(1):68-74
- 8. Sert M,İlkit M,Tetiker T et all. Diabetes mellitus ve ayak dermatomkozları: gerçekten ilişkili mi? Turkısh Journal of Infection 2001;15(3):341-43
- 9. Pièrard GE, Franchimont CP. The nail under fungal siege in patients with type II diabetes mellitus. Mycoses 2005; 48: 339-342
- 0. Gupta AK, Konnikov N, MacDonald P, Prich P, Rodger NW, Edmonds MW, McManus R, Summerbell RC. Prevalence and epidemiology of toenail onychomycosis in diabetic subjects: a multicentre survey. British Journal of Dermatology 1998; 139: 665-671.
- 11. Saunte DML, Holgersen JB, Haedersdal M, Strauss G, Bitsch M, Svendsen OL, Arendrup MC, Sveljgaard EL. Prevalence of toe nail onychomycosis in diabetic patients. Acta Derm Venereol 2006; 86: 425-428
- 12. Romano C, Massai L, Asta F, Signorini AM. Prevalence of dermatophytic skin and nail infections in diabetic patients. Mycoses 2001; 44: 83-86
- 13. Buxton PK, Milne LJR, Prescott RJ et all. The prevalence of dermatophyte infection in well-controlled diabetics and the response to trichopyton antigen. British Journal of Dermatology 1996; 134: 900-903.,
- 14. Bouguerra R, Essais O, Sebai N, Ben Salem L, Amari H, Kammoun MR, Chaker E, Zidi B, Ben Salama C. Prevalence and clinical aspects of superficial mycosis in hospitalized diabetic patients in Tunisia. Med Mal Infect 2004; 34(5): 201-205.
- 15. Mayser P, Hensel J, Thoma W, Podobinska, Geiger, Ulbricht H, Haak T. Prevalence of fungal foot infections in patients with diabetes mellitus type 1-underestimation of moccasin-type tinea. Exp Clin Endocrinol Diabetes 2004; 112: 264-268.
- 16. Yosipovitch G, Hodak E, Vardi P, Shraga I, Karp M, Sprecher E, David M. The prevalence of cutaneous manifestations in IDDM patients and their association with diabetes risk factors and microvascular complications. Diabetes Care 1998; 21(4): 506-509.
- 17. Hekimsoy Z, Toprak Ö, Bozdağ KE, Aslan SL. Diabetik hastalardaki deri bulguları. T Klin J Dermatol 2002; 12: 181-184.
- 18. Rich P, Hare A. Onychomycosis in a special patient population: focus on the diabetic. International Journal of Dermatology 1999; 38(2): 17-19.
- 19. Rosseeuw D, Katsambas A, Burzykowski T. The risk of fungal foot infections in diabetic patients. J Eur Acad Dermatol Venereol 1999; 12: 220.
- 20. Gupta AK, Ryder J, Summerbell RC. Fungal infections in immunocompromised patients. Journal European Academy of Dermatology and Venereology 2003; 17: 1-2.
- 21. Dogra S, Kumar B, Bhansali A, Chakrabarty A. Epidemiology of onychomycosis in patients with diabetes mellitus in India. International; Journal of Dermatology 2002;41: 647-651.
- 22. Gülcan A. The factors of onychomycosis and antifungal susceptibilities in patients with diabetes mellitus. Abant İzzet Baysal University Faculty of Medicine,Department of Microbiology and Clinical Microbiology, Düzce;2004.
- 23. Gupta AK, Jain HC, Lynde CW, Macdonald P, Cooper EA, Summerbell RC. Prevalence and epidemiology of onychomycosis in patients visiting physicians’ offices: a multicenter Canadian survey of 15,000 patients. J Am Acad Dermatol 2000; 43(2): 244-248.
- 24. Alteras I, Saryt E. Prevalence of pathogenic fungi in the toe-webs and toe-nails of diabetic patients. Mycopathologia 1979; 16: 157-159.
- 25. Ozcan D, Seçkin D, Demirbilek M. In vitro antifungal susceptibility of dermatophyte strains causing tinea pedis and onychomycosis in patients with non-insulin-dependent diabetes mellitus: a case–control study. J Eur Acad Dermatol Venereol 2010; 24: 1442–1446.
Year 2020,
, 359 - 365, 27.10.2020
Abstract
Background
Diabetes is an important disease with a frequency of 7.2% that leads to mortality and morbidity and impairs quality of life. The prevalence of skin symptoms in diabetes is 30% and a significant proportion of these are skin infections. The objective of this study was to determine the frequency of onychomycosis and tinea pedis in patients with diabetes mellitus compared to non-diabetic control group with similar age and gender, to evaluate diabetic and epidemiological risk factors, and to determine the pathogens in onychomycosis and tinea pedis.
Materyal and methods
A total of 167 patients followed-up for diabetes were enrolled in the study. The control group comprised 150 individuals with similar age and gender characteristics with the diabetic group. The demographic data for each subject were recorded in a questionnaire form by face-to-face interview with the consent of the patient. Data recorded in this questionnaire included age, gender, type and duration of diabetes, and hemoglobin A1c (HbA1C) levels. Clinical samples were collected separately from the toenails and the surrounding area and from the plantar and interdigital area of the feet for direct microscopic examination and culture.
Results
The co-occurrence of diabetes and tinea pedis was significantly increased in this study. T. rubrum growth was seen in a substantial proportion of the cases and intertriginous type was the most frequently observed type, similar to normal population. In this study, the correlation between diabetes types and onychomycosis or tinea pedis was not significant while longer duration of diabetes was found to increase susceptibility to fungal infections.
Conclusion
It was concluded that the frequency of onychomycosis and tinea pedis, as an important cause of morbidity in diabetes, should routinely be surveyed, any infections should be treated, and patients should be given training regarding the protective measures and risk factors.
Keywords
References
- 1. Perez MI, Kohn SR. Cutaneous manifestations of diabetes mellitus. J Am Acad Dermatol 1995; 32(4): 143-144.
- 2. Bouguerra R, Essais O, Sebai N, Ben Salem L, Amari H, Kammoun MR,et all. Prevalence and clinical aspects of superficial mycosis in hospitalized diabetic patients in Tunisia. Med Mal Infect 2004; 34(5): 201-205.
- 3. Tan JS, Joseph WS. Common fungal infections of the feet in patients with diabetes mellitus. Drugs Aging 2004; 21(2): 101-112.
- 4. Somolinos AL, Sànchez JL. Prevalence of dermatophytosis in patients with diabetes. J Am Acad Dermatol 1992; 26: 408-410.
- 5. Dogra S, Kumar B, Bhansali A, Chakrabarty A. Epidemiology of onychomycosis in patients with diabetes mellitus in India. International Journal of Dermatology 2002; 41: 647-651.
- 6. Aşçı Z, Seyrek A, Kizirgil A, Yılmaz M. Diyabetli hastalarda tinea unguium araştırılması. Turkish Journal of Infection 1996; 10(4): 365-367.
- 7. Oz Y,Oz A, Qoaraan I, Balta I. Prevalence and epidemiology of tinea pedis and toenail onychomycosis and antifungal susceptibility of the causative agents in patients with type 2 diabetes in Turkey Int J Dermatol. 2017 Jan;56(1):68-74
- 8. Sert M,İlkit M,Tetiker T et all. Diabetes mellitus ve ayak dermatomkozları: gerçekten ilişkili mi? Turkısh Journal of Infection 2001;15(3):341-43
- 9. Pièrard GE, Franchimont CP. The nail under fungal siege in patients with type II diabetes mellitus. Mycoses 2005; 48: 339-342
- 0. Gupta AK, Konnikov N, MacDonald P, Prich P, Rodger NW, Edmonds MW, McManus R, Summerbell RC. Prevalence and epidemiology of toenail onychomycosis in diabetic subjects: a multicentre survey. British Journal of Dermatology 1998; 139: 665-671.
- 11. Saunte DML, Holgersen JB, Haedersdal M, Strauss G, Bitsch M, Svendsen OL, Arendrup MC, Sveljgaard EL. Prevalence of toe nail onychomycosis in diabetic patients. Acta Derm Venereol 2006; 86: 425-428
- 12. Romano C, Massai L, Asta F, Signorini AM. Prevalence of dermatophytic skin and nail infections in diabetic patients. Mycoses 2001; 44: 83-86
- 13. Buxton PK, Milne LJR, Prescott RJ et all. The prevalence of dermatophyte infection in well-controlled diabetics and the response to trichopyton antigen. British Journal of Dermatology 1996; 134: 900-903.,
- 14. Bouguerra R, Essais O, Sebai N, Ben Salem L, Amari H, Kammoun MR, Chaker E, Zidi B, Ben Salama C. Prevalence and clinical aspects of superficial mycosis in hospitalized diabetic patients in Tunisia. Med Mal Infect 2004; 34(5): 201-205.
- 15. Mayser P, Hensel J, Thoma W, Podobinska, Geiger, Ulbricht H, Haak T. Prevalence of fungal foot infections in patients with diabetes mellitus type 1-underestimation of moccasin-type tinea. Exp Clin Endocrinol Diabetes 2004; 112: 264-268.
- 16. Yosipovitch G, Hodak E, Vardi P, Shraga I, Karp M, Sprecher E, David M. The prevalence of cutaneous manifestations in IDDM patients and their association with diabetes risk factors and microvascular complications. Diabetes Care 1998; 21(4): 506-509.
- 17. Hekimsoy Z, Toprak Ö, Bozdağ KE, Aslan SL. Diabetik hastalardaki deri bulguları. T Klin J Dermatol 2002; 12: 181-184.
- 18. Rich P, Hare A. Onychomycosis in a special patient population: focus on the diabetic. International Journal of Dermatology 1999; 38(2): 17-19.
- 19. Rosseeuw D, Katsambas A, Burzykowski T. The risk of fungal foot infections in diabetic patients. J Eur Acad Dermatol Venereol 1999; 12: 220.
- 20. Gupta AK, Ryder J, Summerbell RC. Fungal infections in immunocompromised patients. Journal European Academy of Dermatology and Venereology 2003; 17: 1-2.
- 21. Dogra S, Kumar B, Bhansali A, Chakrabarty A. Epidemiology of onychomycosis in patients with diabetes mellitus in India. International; Journal of Dermatology 2002;41: 647-651.
- 22. Gülcan A. The factors of onychomycosis and antifungal susceptibilities in patients with diabetes mellitus. Abant İzzet Baysal University Faculty of Medicine,Department of Microbiology and Clinical Microbiology, Düzce;2004.
- 23. Gupta AK, Jain HC, Lynde CW, Macdonald P, Cooper EA, Summerbell RC. Prevalence and epidemiology of onychomycosis in patients visiting physicians’ offices: a multicenter Canadian survey of 15,000 patients. J Am Acad Dermatol 2000; 43(2): 244-248.
- 24. Alteras I, Saryt E. Prevalence of pathogenic fungi in the toe-webs and toe-nails of diabetic patients. Mycopathologia 1979; 16: 157-159.
- 25. Ozcan D, Seçkin D, Demirbilek M. In vitro antifungal susceptibility of dermatophyte strains causing tinea pedis and onychomycosis in patients with non-insulin-dependent diabetes mellitus: a case–control study. J Eur Acad Dermatol Venereol 2010; 24: 1442–1446.
There are 25 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Medical Science Research Articles |
| Authors | |
| Publication Date | October 27, 2020 |
| Acceptance Date | October 27, 2020 |
| Published in Issue | Year 2020 |