Research Article
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Year 2020, , 458 - 465, 31.12.2020
https://doi.org/10.7197/cmj.835306

Abstract

References

  • 1- Svatikova, A., & Kopecky, S. L. (2020). Why and How Cardiovascular Screening Should Be Implemented in Sexual Medicine Practice: Erectile Dysfunction and Cardiovascular Disease. The Journal of Sexual Medicine, 17(6), 1045-1048.
  • 2- Levy, J. (2002). Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. The British Journal of Diabetes & Vascular Disease, 2(4), 278-280.
  • 3- Kendirci, M., Asci, R., Yaman, Ö., Cayan, S., Orhan, I., Usta, M. F., ... & Kadioglu, A. (2014). Prevalence of male pelvic dysfunction: results from the Turkish society of andrology male sexual health study group. Andrology, 2(2), 219-224.
  • 4- Shamloul, R., & Ghanem, H. (2013). Erectile dysfunction. The Lancet, 381(9861), 153-165.
  • 5- Cazzaniga, W., Capogrosso, P., Montorsi, F., Salonia, A., URI, I. O. S. R., & Boeri, L. (2020). Erectile Dysfunction. Urologic Principles and Practice, 159.
  • 6- Rusiecki, L., Zdrojowy, R., Gebala, J., Rabijewski, M., Sobieszczańska, M., Smoliński, R., ... & Kałka, D. (2020). Sexual health in Polish elderly men with coronary artery disease: importance, expectations, and reality. Asian Journal of Andrology.
  • 7- Konstantinovsky, A., Tamir, S., Katz, G., Tzischinsky, O., Kuchersky, N., Blum, N., & Blum, A. (2019). Erectile Dysfunction, Sleep Disorders, and Endothelial Function. The Israel Medical Association journal: IMAJ, 21(6), 408-411.
  • 8- Wan, Z. H., Zhang, Y. J., Chen, L., Guo, Y. L., Li, G. H., Wu, D., & Wang, Y. (2019). G protein-coupled receptor kinase 2 inhibition improves erectile function through amelioration of endothelial dysfunction and oxidative stress in a rat model of type 2 diabetes. Asian journal of andrology, 21(1), 74.
  • 9- Ma, B. O., Shim, S. G., & Yang, H. J. (2015). Association of erectile dysfunction with depression in patients with chronic viral hepatitis. World Journal of Gastroenterology: WJG, 21(18), 5641.
  • 10- Kim, M., Kim, S. Y., Rou, W. S., Hwang, S. W., & Lee, B. S. (2015). Erectile dysfunction in patients with liver disease related to chronic hepatitis B. Clinical and molecular hepatology, 21(4), 352.
  • 11- Chung, S. D., Keller, J. J., Liang, Y. C., & Lin, H. C. (2012). Association between viral hepatitis and erectile dysfunction: A population‐based case‐control analysis. The Journal of Sexual Medicine, 9(5), 1295-1302.
  • 12- Fusco, F., D'Anzeo, G., Rossi, A., Sciorio, C., Buonomo, A. R., d'Emmanuele di Villa Bianca, R., ... & Gentile, I. (2013). Erectile dysfunction in patients with chronic viral hepatitis: a systematic review of the literature. Expert opinion on pharmacotherapy, 14(18), 2533-2544.
  • 13- Rosen, R. C., Riley, A., Wagner, G., Osterloh, I. H., Kirkpatrick, J., & Mishra, A. (1997). The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology, 49(6), 822-830.
  • 14- Gareri, P., Castagna, A., Francomano, D., Cerminara, G., & De Fazio, P. (2014). Erectile dysfunction in the elderly: an old widespread issue with novel treatment perspectives. International journal of endocrinology, 2014.
  • 15- Simsek, I., Aslan, G., Akarsu, M., Koseoglu, H., & Esen, A. (2005). Assessment of sexual functions in patients with chronic liver disease. International journal of impotence research, 17(4), 343-345.
  • 16- Ferri, C., Bertozzi, M. A., & Zignego, A. L. (2002). Erectile dysfunction and hepatitis C virus infection. Jama, 288(6), 698-699.
  • 17- Huyghe, E., Kamar, N., Wagner, F., Capietto, A. H., El-Kahwaji, L., Muscari, F., ... & Rostaing, L. (2009). Erectile dysfunction in end-stage liver disease men. The journal of sexual medicine, 6(5), 1395-1401.
  • 18- Vergniol, J., Duc, S., Hou, G., Hiriart, J. B., Foucher, J., Chenus, F., ... & De Lédinghen, V. (2016). Sexual quality of life is impaired in patients with chronic hepatitis C. International Journal of Impotence Research, 28(2), 68-73.
  • 19- Paternostro, R., Heinisch, B. B., Reiberger, T., Mandorfer, M., Schwarzer, R., Seeland, B., ... & Ferlitsch, A. (2018). Erectile dysfunction in cirrhosis is impacted by liver dysfunction, portal hypertension, diabetes and arterial hypertension. Liver International, 38(8), 1427-1436.

The relationship between chronic viral hepatitis and erectile dysfunction in male patients more than 65 years old

Year 2020, , 458 - 465, 31.12.2020
https://doi.org/10.7197/cmj.835306

Abstract

Objective: Erectile dysfunction is defined as the incomplete failure of penile erection for satisfying sexual intercourse. Its incidence is quite high in male patients over 65 years of age. Many diseases, such as Diabetes Mellitus, obesity, and psychiatric diseases, affect erectile dysfunction. In our study, we aimed to show the relationship between chronic viral hepatitis and erectile dysfunction in male patients over 65 years of age. 
Method: A single-center retrospective study. Sixty-five male patients over 65 years old, 35 chronic viral hepatitis, 30 healthy controls were included in our study. Patients with comorbidities facilitating erectile dysfunction such as diabetes mellitus, obesity, and psychiatric disease were excluded from our study. 
Results: Erectile dysfunction was found in 49 of the 65 patients included in our study. There was no significant difference between HDL, Triglyceride, AST, ALT, GGT, LDH, Total Protein, and Albumin levels in the control group with hepatitis (p> 0.05). On the other hand, age and erectile dysfunction were found statistically significantly higher in the group with hepatitis (p <0.001, p = 0.002, respectively). IIEF, Total cholesterol and LDL were statistically significantly higher in the Control group (p <0.001, p = 0.01 and p = 0.02, respectively). 
Conclusions: The incidence of erectile dysfunction was higher in male patients over 65 years of age with chronic viral hepatitis compared to the control group. There was a significant relationship between erectile dysfunction and chronic viral hepatitis and advanced age.

References

  • 1- Svatikova, A., & Kopecky, S. L. (2020). Why and How Cardiovascular Screening Should Be Implemented in Sexual Medicine Practice: Erectile Dysfunction and Cardiovascular Disease. The Journal of Sexual Medicine, 17(6), 1045-1048.
  • 2- Levy, J. (2002). Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. The British Journal of Diabetes & Vascular Disease, 2(4), 278-280.
  • 3- Kendirci, M., Asci, R., Yaman, Ö., Cayan, S., Orhan, I., Usta, M. F., ... & Kadioglu, A. (2014). Prevalence of male pelvic dysfunction: results from the Turkish society of andrology male sexual health study group. Andrology, 2(2), 219-224.
  • 4- Shamloul, R., & Ghanem, H. (2013). Erectile dysfunction. The Lancet, 381(9861), 153-165.
  • 5- Cazzaniga, W., Capogrosso, P., Montorsi, F., Salonia, A., URI, I. O. S. R., & Boeri, L. (2020). Erectile Dysfunction. Urologic Principles and Practice, 159.
  • 6- Rusiecki, L., Zdrojowy, R., Gebala, J., Rabijewski, M., Sobieszczańska, M., Smoliński, R., ... & Kałka, D. (2020). Sexual health in Polish elderly men with coronary artery disease: importance, expectations, and reality. Asian Journal of Andrology.
  • 7- Konstantinovsky, A., Tamir, S., Katz, G., Tzischinsky, O., Kuchersky, N., Blum, N., & Blum, A. (2019). Erectile Dysfunction, Sleep Disorders, and Endothelial Function. The Israel Medical Association journal: IMAJ, 21(6), 408-411.
  • 8- Wan, Z. H., Zhang, Y. J., Chen, L., Guo, Y. L., Li, G. H., Wu, D., & Wang, Y. (2019). G protein-coupled receptor kinase 2 inhibition improves erectile function through amelioration of endothelial dysfunction and oxidative stress in a rat model of type 2 diabetes. Asian journal of andrology, 21(1), 74.
  • 9- Ma, B. O., Shim, S. G., & Yang, H. J. (2015). Association of erectile dysfunction with depression in patients with chronic viral hepatitis. World Journal of Gastroenterology: WJG, 21(18), 5641.
  • 10- Kim, M., Kim, S. Y., Rou, W. S., Hwang, S. W., & Lee, B. S. (2015). Erectile dysfunction in patients with liver disease related to chronic hepatitis B. Clinical and molecular hepatology, 21(4), 352.
  • 11- Chung, S. D., Keller, J. J., Liang, Y. C., & Lin, H. C. (2012). Association between viral hepatitis and erectile dysfunction: A population‐based case‐control analysis. The Journal of Sexual Medicine, 9(5), 1295-1302.
  • 12- Fusco, F., D'Anzeo, G., Rossi, A., Sciorio, C., Buonomo, A. R., d'Emmanuele di Villa Bianca, R., ... & Gentile, I. (2013). Erectile dysfunction in patients with chronic viral hepatitis: a systematic review of the literature. Expert opinion on pharmacotherapy, 14(18), 2533-2544.
  • 13- Rosen, R. C., Riley, A., Wagner, G., Osterloh, I. H., Kirkpatrick, J., & Mishra, A. (1997). The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology, 49(6), 822-830.
  • 14- Gareri, P., Castagna, A., Francomano, D., Cerminara, G., & De Fazio, P. (2014). Erectile dysfunction in the elderly: an old widespread issue with novel treatment perspectives. International journal of endocrinology, 2014.
  • 15- Simsek, I., Aslan, G., Akarsu, M., Koseoglu, H., & Esen, A. (2005). Assessment of sexual functions in patients with chronic liver disease. International journal of impotence research, 17(4), 343-345.
  • 16- Ferri, C., Bertozzi, M. A., & Zignego, A. L. (2002). Erectile dysfunction and hepatitis C virus infection. Jama, 288(6), 698-699.
  • 17- Huyghe, E., Kamar, N., Wagner, F., Capietto, A. H., El-Kahwaji, L., Muscari, F., ... & Rostaing, L. (2009). Erectile dysfunction in end-stage liver disease men. The journal of sexual medicine, 6(5), 1395-1401.
  • 18- Vergniol, J., Duc, S., Hou, G., Hiriart, J. B., Foucher, J., Chenus, F., ... & De Lédinghen, V. (2016). Sexual quality of life is impaired in patients with chronic hepatitis C. International Journal of Impotence Research, 28(2), 68-73.
  • 19- Paternostro, R., Heinisch, B. B., Reiberger, T., Mandorfer, M., Schwarzer, R., Seeland, B., ... & Ferlitsch, A. (2018). Erectile dysfunction in cirrhosis is impacted by liver dysfunction, portal hypertension, diabetes and arterial hypertension. Liver International, 38(8), 1427-1436.
There are 19 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Medical Science Research Articles
Authors

Sedat Taştemur 0000-0003-0534-2520

Ahmet Aktaş 0000-0001-9464-0700

Publication Date December 31, 2020
Acceptance Date December 17, 2020
Published in Issue Year 2020

Cite

AMA Taştemur S, Aktaş A. The relationship between chronic viral hepatitis and erectile dysfunction in male patients more than 65 years old. CMJ. December 2020;42(4):458-465. doi:10.7197/cmj.835306