Research Article
Year 2021,
, 211 - 216, 30.09.2021
Abstract
References
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- Referans4. Moreira MA, Barbosa MA, Queiroz MC, Teixeira KI, Torres PP, Santana Júnior PJ, et al. Pulmonary changes on HRCT scans in nonsmoking females with COPD due to wood smoke exposure. J Bras Pneumol 2013; 39:155 163.
- Referans5. Noble PW, Barkauskas CE, Jiang D. Pulmonary fibrosis: patterns and perpetrators. J Clin Invest 2012; 122(8):2756-2762.
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- Referans7. Aygün C, Gözel N, Demirel U, Yalnız M, Özercan İH, Bahçecioğlu İH. Kronik viral hepatit B tanısı olan hastalarda serum GGT düzeyi ile karaciğer fibrozu ilişkisi. Fırat Medical Journal 2010; 15:74-78.
- Referans8. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, Gudat F et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22:696–699.
- Referans9. Söker G, Gülek B, Öztürk AB, Karabıyık Ö, Akın MA, Kaya Ö, Dilek O, Yılmaz C. The Value of Fibrosis Index in Discrimination of Chronic Hepatitis and Cirrhosis. Med Bull Haseki 2017; 55:212-215.
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- Referans11. Soker G, Bahadir Ozturk A, Gulek B, Kuscu F, Bilge Doğan U, Yilmaz C. Doppler ultrasonography helps discriminate between cirrhotic and non-cirrhotic patients with viral B and C hepatitis. Diagn Interv Imaging 2016; 97:339-345.
- Referans12. Rockey DC, Bell PD, Hill JA. Fibrosis–a common pathway to organ injury and failure. N Engl J Med 2015; 372:1138-1149.
- Referans13. Walters EH, du Bois RM. Immunology and management of interstitial lung diseases London: Chapman & Hall Medical, 1995.
Is there a relation between hepatic fibrosis due to chronic hepatitis B and C, and fibrosis of the lung?
Abstract
Objective: The aim of this study was to find out if the process of hepatic fibrosis due to hepatitis B and C accentuates the development of fibrosis of the lungs.
Method: Cases with histories of parenchymal hepatic biopsies were scanned retrospectively, which had been biopsied due to hepatitis B and C diagnoses. Among these patients, those who had undergone a computed tomographic (CT) examination of the chest during the year following the biopsy procedure were investigated for signs of lung fibrosis. The hepatic biopsy results were categorized into two groups on the basis of the modified hepatic activity index, and these were evaluated in comparison with the lung fibrosis findings diagnosed at CT.
Results: Findings of lung fibrosis were found in 43.8 % of the patients with hepatitis B and C. When the group with the pathological diagnosis of hepatic fibrosis (Stages 1-5) was compared with the no-hepatic-fibrosis group, it was found that no statistically significant difference existed between these two groups, in terms of positive or negative lung fibrosis findings at CT of the chest.
Conclusions: There is no correlation between the development of hepatic fibrosis and lung fibrosis.
References
- Referans1. Makarev E, Izumchenko E, Aihara F, Wysocki PT, Zhu Q, Buzdin A. Common pathway signature in lung and liver fibrosis. Cell Cycle 2016; 15(13):1667-1673.
- Referans2. Cotran RS, Kumar V, Collins T. Pathology basic of disease. Philadelphia: WB Saunders Co, 1999.
- Referans3. Resorlu M, Arslan M, Karatag O, Adam G. Thorax Computed Tomography Findings in Patients with Erectile Dysfunction. J Clin Imaging Sci 2017; 7:25.
- Referans4. Moreira MA, Barbosa MA, Queiroz MC, Teixeira KI, Torres PP, Santana Júnior PJ, et al. Pulmonary changes on HRCT scans in nonsmoking females with COPD due to wood smoke exposure. J Bras Pneumol 2013; 39:155 163.
- Referans5. Noble PW, Barkauskas CE, Jiang D. Pulmonary fibrosis: patterns and perpetrators. J Clin Invest 2012; 122(8):2756-2762.
- Referans6. Wallis A, Spinks K. The diagnosis and management of interstitial lung diseases BMJ 2015; 350:h2072.
- Referans7. Aygün C, Gözel N, Demirel U, Yalnız M, Özercan İH, Bahçecioğlu İH. Kronik viral hepatit B tanısı olan hastalarda serum GGT düzeyi ile karaciğer fibrozu ilişkisi. Fırat Medical Journal 2010; 15:74-78.
- Referans8. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, Gudat F et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22:696–699.
- Referans9. Söker G, Gülek B, Öztürk AB, Karabıyık Ö, Akın MA, Kaya Ö, Dilek O, Yılmaz C. The Value of Fibrosis Index in Discrimination of Chronic Hepatitis and Cirrhosis. Med Bull Haseki 2017; 55:212-215.
- Referans10. Davoudi Y, Layegh P, Sima H, Tatari S, Faghani R. Diagnostic Value of Conventional and Doppler Ultrasound Findings in Liver Fibrosis in Patients with Chronic Viral Hepatitis. J Med Ultrasound 2015; 23:123-128.
- Referans11. Soker G, Bahadir Ozturk A, Gulek B, Kuscu F, Bilge Doğan U, Yilmaz C. Doppler ultrasonography helps discriminate between cirrhotic and non-cirrhotic patients with viral B and C hepatitis. Diagn Interv Imaging 2016; 97:339-345.
- Referans12. Rockey DC, Bell PD, Hill JA. Fibrosis–a common pathway to organ injury and failure. N Engl J Med 2015; 372:1138-1149.
- Referans13. Walters EH, du Bois RM. Immunology and management of interstitial lung diseases London: Chapman & Hall Medical, 1995.
There are 13 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Medical Science Research Articles |
| Authors | |
| Publication Date | September 30, 2021 |
| Acceptance Date | September 20, 2021 |
| Published in Issue | Year 2021 |