Cervical squamous intraepithelial neoplasia grade 1: Recurrence, persistence, and progression in untreated women
Abstract
Objective: Low grade cervical intraepithelial neoplasia (CIN) is a relatively common disorder. The course of disease including recurrence, persistence, and progression in untreated women is not well-known. The aim of the present study was to determine the natural history of CIN 1 during a follow-up period of 3 years.
Method: This retrospective study involved data extracted from the medical files of 545 patients diagnosed with CIN 1 between 2009 and 2015 in the obstetrics and gynecology department of a tertiary care center. Initial cervical smear results were compared to those on the follow-up visits at 1st, 2nd and 3rd years.
Results: Comparison of initial smear results with follow-up samples yielded significant improvements on 1st, 2nd, and 3rd years (p<0.001 for all). In patients ≤ 44 years of age, improvement in smear results on the 2nd year was more noteworthy than those in patients ˃ 44 years (p=0.011).
Conclusions: Results of the present study imply that To conclude, our results demonstrated that low-grade CIN lesions are less likely to display a progressive course. Therefore, prolongation of the screening intervals may be logical for the avoidance of unnecessary visits and procedures, improvement of the quality of life and cost-effectivity.Keywords
References
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Publication Date
March 20, 2018
Submission Date
August 3, 2017
Acceptance Date
March 5, 2018
Published in Issue
Year 1970 Volume: 40 Number: 1