Cervical squamous intraepithelial neoplasia grade 1: Recurrence, persistence, and progression in untreated women
Abstract
Objective: Low grade cervical intraepithelial neoplasia (CIN) is a relatively common disorder. The course of disease including recurrence, persistence, and progression in untreated women is not well-known. The aim of the present study was to determine the natural history of CIN 1 during a follow-up period of 3 years.
Method: This retrospective study involved data extracted from the medical files of 545 patients diagnosed with CIN 1 between 2009 and 2015 in the obstetrics and gynecology department of a tertiary care center. Initial cervical smear results were compared to those on the follow-up visits at 1st, 2nd and 3rd years.
Results: Comparison of initial smear results with follow-up samples yielded significant improvements on 1st, 2nd, and 3rd years (p<0.001 for all). In patients ≤ 44 years of age, improvement in smear results on the 2nd year was more noteworthy than those in patients ˃ 44 years (p=0.011).
Conclusions: Results of the present study imply that To conclude, our results demonstrated that low-grade CIN lesions are less likely to display a progressive course. Therefore, prolongation of the screening intervals may be logical for the avoidance of unnecessary visits and procedures, improvement of the quality of life and cost-effectivity.Keywords
Kaynakça
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Ayrıntılar
Birincil Dil
İngilizce
Konular
Sağlık Kurumları Yönetimi
Bölüm
Araştırma Makalesi
Yayımlanma Tarihi
20 Mart 2018
Gönderilme Tarihi
3 Ağustos 2017
Kabul Tarihi
5 Mart 2018
Yayımlandığı Sayı
Yıl 2018 Cilt: 40 Sayı: 1