Research Article
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Year 2019, Volume: 41 Issue: 1, 75 - 81, 28.03.2019
https://doi.org/10.7197/223.vi.530580

Abstract


References

  • 1. Goenka AH, Herts BR, Obuchowski NA, Primark AN, Dong F, Karim W, Baker ME. Effect of reduced radiation exposure and iterative reconstruction on detection of lowcontrast low-attenuation lesions in an anthropomorphic liver phantom: an 18-reader study. Radiology 2014; 1:154–1632. Erdi YE. Quantification of thyroid volume. Journal of Nuclear Medicine 1997; 6:1002.3.Hamilton D. Single Photon Planar Imaging. In. Hamilton D, David I (Eds). Single Photon Planar Imaging Diagnostic Nuclear Medicine A Physics Perspective. 1st Edition. Berlin: Springer, 2004; pp 115-136.4. Aliyev A, Metin H. Tiroit Kanserlerinde Tek Foton Emisyon Tomografisi/Bilgisayarlı Tomografi Görüntüleme. Nuclear Medicine Seminars / Nükleer Tıp Seminerleri 2016; pp 21-30.5. Rockoff SD, Goodenough DJ, McIntire KR. Theoretical limitations in the immunodiagnostic imaging of cancer with computed tomography and nuclear scanning. American Association for Cancer Research 1980; 8: 3054-3058.6. Bradwell AR, Fairweather DS, Dykes PW, Keeling A, Vaughan A, Taylor J. Limiting factors in the localization of tumors with radiolabeled antibodies, Immunology Today 1985; 5:163-170.7. Meikle SR, Dahlbom M. Positron emission tomography. In: Murray IPC., Ell PJ (Eds). Nuclear medicine in clinical diagnosis and treatment. New York: Churchill Livingston , 2006; pp 350-351.8. Maurer AH, Caroline DF, Jadali FJ, Manzone TA, Maier WP, Au FC, Schnall SF. Limitations of craniocaudal thallium-201 and technetium-99m-sestamibi mammoscintigraphy, Journal of Nuclear Medicine 1995; 9:1696-1700.9. Weber W, Bartenstein P, Gross MW, Kinzel GD, Daschner H, Feldmann HJ, Reidel G., Ziegler SI, Lumenta C, Molls M, Schwaiger M. Flourine-18-FDG PET and Iodine-123-IMT SPECT in the evaluation of brain tumors, Journal of Nuclear Medicine 1997; 5:802-808.10. Erdi AK, Erdi YE, Yorke ED, Wessels BW. Treatment planning for radioimmunotherapy, Physics in Medicine and Biology 1996; 10:2009-2026.11. Goodenough DJ, Atkins FB. Theoretical limitations of tumor imaging. In: Srivastava S(Eds). Radiolabeled monoclonal antibodies for imaging and therapy, New York: Plenum Publishing Corporation, 1998; pp 152-155.12. Jaszczak RJ, Coleman RE, Whitehead FR. Physical factors affecting quantitative measurements using camera-based single photon emission computed tomography, IEEE Nuclear and Plasma Sciences Society 1981; 1:69-80.13. Rose A. The visual process. In: Rose A(Eds).Vision: Human and Electronics. 1st ed. New York: Plenum Press, 1973; pp 1-27.14. Schneider DF, Ojomo KA, Chen H, Sippel RS. Remnant Uptake as a Postoperative Oncologic Quality Indicator. Thyroid 2013; 10:1269-1276. 15. Bugby SL, Lees JE, Ng AH, Alqahtani MS, Perkins AC. Investigation of an SFOV hybrid gamma camera for thyroid imaging. Physica Medica 2016; 1: 290–296.16. Hassan FU, Mohan FK. Clinical Utility of SPECT/CT Imaging Post-Radioiodine Therapy: Does It Enhance Patient Management in Thyroid Cancer?, European Thyroid Journal 2015; 4:239–245.17.https://www.healthcare.siemens.com.au/molecular-imaging/spect-and-spect-ct/symbia-t. Retrieved January 2, 2019. 18.http://santaxweb.dk/wp-content/uploads/2016/08/THB_1014_web.pdf. Retrieved January 2, 2019.

Lesion detection in conventional gamma camera, SPECT and SPECT / CT systems: Phantom study

Year 2019, Volume: 41 Issue: 1, 75 - 81, 28.03.2019
https://doi.org/10.7197/223.vi.530580

Abstract

Objective: It was aimed to create special phantom to be used for benchmarking the
lesion detectability of planar, SPECT and SPECT / CT systems by computing the corresponding
contrast (C) and contrast / noise ratio (CNR) of the lesions with different
activity concentrations.

Method: In the study,
the phantom was equiped with with four lesions filled with radioiodine (131I).
The phantom’s planar images were acquired by two different gamma cameras with
small field of view (SFOV) and large field of view (LFOV). Tomographic images
were obtained from SPECT and SPECT / CT scans. Contrast (C) and
contrast-to-noise ratio (CNR) were calculated by delineating areas of interest
(ROI) over the tubes and background with different activity concentrations in
the phantom.

Results: As the camera’s
field of view increased, the related contrast and CNR values increased
partially. Contrast and CNR values of SPECT and SPECT / CT images were
significantly higher than planer images.







Conclusions:
It was found that the superior lesion
detectability might be achieved by SPECT or SPECT / CT (AC) imaging techniques.

References

  • 1. Goenka AH, Herts BR, Obuchowski NA, Primark AN, Dong F, Karim W, Baker ME. Effect of reduced radiation exposure and iterative reconstruction on detection of lowcontrast low-attenuation lesions in an anthropomorphic liver phantom: an 18-reader study. Radiology 2014; 1:154–1632. Erdi YE. Quantification of thyroid volume. Journal of Nuclear Medicine 1997; 6:1002.3.Hamilton D. Single Photon Planar Imaging. In. Hamilton D, David I (Eds). Single Photon Planar Imaging Diagnostic Nuclear Medicine A Physics Perspective. 1st Edition. Berlin: Springer, 2004; pp 115-136.4. Aliyev A, Metin H. Tiroit Kanserlerinde Tek Foton Emisyon Tomografisi/Bilgisayarlı Tomografi Görüntüleme. Nuclear Medicine Seminars / Nükleer Tıp Seminerleri 2016; pp 21-30.5. Rockoff SD, Goodenough DJ, McIntire KR. Theoretical limitations in the immunodiagnostic imaging of cancer with computed tomography and nuclear scanning. American Association for Cancer Research 1980; 8: 3054-3058.6. Bradwell AR, Fairweather DS, Dykes PW, Keeling A, Vaughan A, Taylor J. Limiting factors in the localization of tumors with radiolabeled antibodies, Immunology Today 1985; 5:163-170.7. Meikle SR, Dahlbom M. Positron emission tomography. In: Murray IPC., Ell PJ (Eds). Nuclear medicine in clinical diagnosis and treatment. New York: Churchill Livingston , 2006; pp 350-351.8. Maurer AH, Caroline DF, Jadali FJ, Manzone TA, Maier WP, Au FC, Schnall SF. Limitations of craniocaudal thallium-201 and technetium-99m-sestamibi mammoscintigraphy, Journal of Nuclear Medicine 1995; 9:1696-1700.9. Weber W, Bartenstein P, Gross MW, Kinzel GD, Daschner H, Feldmann HJ, Reidel G., Ziegler SI, Lumenta C, Molls M, Schwaiger M. Flourine-18-FDG PET and Iodine-123-IMT SPECT in the evaluation of brain tumors, Journal of Nuclear Medicine 1997; 5:802-808.10. Erdi AK, Erdi YE, Yorke ED, Wessels BW. Treatment planning for radioimmunotherapy, Physics in Medicine and Biology 1996; 10:2009-2026.11. Goodenough DJ, Atkins FB. Theoretical limitations of tumor imaging. In: Srivastava S(Eds). Radiolabeled monoclonal antibodies for imaging and therapy, New York: Plenum Publishing Corporation, 1998; pp 152-155.12. Jaszczak RJ, Coleman RE, Whitehead FR. Physical factors affecting quantitative measurements using camera-based single photon emission computed tomography, IEEE Nuclear and Plasma Sciences Society 1981; 1:69-80.13. Rose A. The visual process. In: Rose A(Eds).Vision: Human and Electronics. 1st ed. New York: Plenum Press, 1973; pp 1-27.14. Schneider DF, Ojomo KA, Chen H, Sippel RS. Remnant Uptake as a Postoperative Oncologic Quality Indicator. Thyroid 2013; 10:1269-1276. 15. Bugby SL, Lees JE, Ng AH, Alqahtani MS, Perkins AC. Investigation of an SFOV hybrid gamma camera for thyroid imaging. Physica Medica 2016; 1: 290–296.16. Hassan FU, Mohan FK. Clinical Utility of SPECT/CT Imaging Post-Radioiodine Therapy: Does It Enhance Patient Management in Thyroid Cancer?, European Thyroid Journal 2015; 4:239–245.17.https://www.healthcare.siemens.com.au/molecular-imaging/spect-and-spect-ct/symbia-t. Retrieved January 2, 2019. 18.http://santaxweb.dk/wp-content/uploads/2016/08/THB_1014_web.pdf. Retrieved January 2, 2019.
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Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Medical Science Research Articles
Authors

Yağmur Ulusoy 0000-0003-0013-4618

Mert Karagöz

Nami Yeyin

Mustafa Demir

Publication Date March 28, 2019
Acceptance Date March 26, 2019
Published in Issue Year 2019Volume: 41 Issue: 1

Cite

AMA Ulusoy Y, Karagöz M, Yeyin N, Demir M. Lesion detection in conventional gamma camera, SPECT and SPECT / CT systems: Phantom study. CMJ. March 2019;41(1):75-81. doi:10.7197/223.vi.530580