Research Article
Year 2019,
Volume: 41 Issue: 2, 301 - 305, 30.06.2019
Abstract
References
- 1- Theoharides TC, Tsilioni I, Arbetman L, Panagiotidou S, Stewart JM, Gleason RM, et al. Fibromyalgia syndrome in need of effective treatments. J Pharmacol Exp Ther 2015; 355: 255-63.
- 2- Dadabhoy D, Clauw DJ. Therapy insight: fibromyalgia a different type of pain needing a different type of treatment. Nat Clin Pract Rheumatol 2006;2:364-72.
- 3-Albrecht PJ, Rice FL Fibromyalgia syndrome pathology and environmental influences on afflictions with medically unexplained symptoms. Rev Environ Health. 2016; 1:281-94
- 4- Xiao Y, Haynes WL, Michalek JE, Russell IJ. Elevated serum high-sensitivity C-reactive protein levels in fibromyalgia syndrome patients correlate withbodymass index,interleukin-6, interleukin-8, erythrocyte sedimentation rate. Rheumatol Int 2013; 33: 1259–64.
- 5- Ozturk C, Balta S, Balta I, Demirkol S, Celik T, Turker T et al. NeutrophilLymphocyte Ratio and Carotid-Intima Media Thickness in Patients With Behcet Disease Without Cardiovascular Involvement. Angiology 2014; 66: 291-96
- 6- Hoffmann JJ, Nabbe KC, van den Broek NM. Effect of age and gender on reference intervals of red blood cell distribution width (RDW) and mean red cell volume (MCV). Clin Chem Lab Med 2015;53:2015-19
- 7- Lippi G, Targher G, Montagnana M, Salvagno GL, Zoppini G, Guidi GC. Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients. Arch Pathol Lab Med 2009;133:628-32. 8- Song CS, Park DI, Yoon MY, Seok HS, Park JH, Kim HJ et al. Association between red cell distribution width and disease activity in patients with inflammatory bowel disease. Dig Dis Sci 2012;57:1033-38.
- 9- Peng YF, Cao L, Zeng YH, Zhang ZX, Chen D, Zhang Q et al. Platelet to lymphocyte ratio and neutrophil to lymphocyte ratio in patients with rheumatoid arthritis. Open Med (Wars) 2015;10:249-53
- 10-Özer S, Yılmaz, Sönmezgöz E, Karaaslan E, Taşkın S, Bütün İ et al. Simple markers for subclinical inflammation in patients with Familial Mediterranean Fever. Med Sci Monit 2015;21:298-03
- 11- Bäckryd E, Tanum L, Lind AL, Larsson A, Gordh T. Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma. J Pain Res. 2017; 10: 515-25.
- 12- Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Katz RS, Mease P et al. The American Collage of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and Measurement of Symptom Severity. Arthritis Care & Research 2010; 62:600-10
- 13-Burckhardt CS, Clark SR, Bennett RM. The fibromyalgia impact questionnaire: development and validation. J Rheumatol 1991;18:728-33.
- 14- Sarmer S, Ergin S, Yavuzer G. The validity and reliability of the Turkish version of the Fibromyalgia Impact Questionnaire. Rheumatol Int 2000; 20:9-12. 15- Sayılır S. Remarkable Hematological Laboratory Findings in Patients with Fibromyalgia Syndrome. Turk J Osteoporos 2016; 22:121-4
- 16- Boyraz İ, Karakoyun A, Koç B. Determination presence of inflammation with neutrophil/lymphocyte and platelet /lymphocyte ratios in Fibromyalgia Syndrome. Eur J Health Sci 2015;1:15-917- Li J, Chen Q, Luo X, Hong J, Pan K, Lin X et al. Neutrophil-toLymphocyte Ratio Positively Correlates to Age in Healthy Population. J Clin Lab Anal 2015; 29: 437-4318- Imtiaz F, Shafique K, Mirza SS, Ayoob Z, Vart P, Rao S. Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population. Int Arch Med 2012;5:2. 19-Tousoulis D, Antoniades C, Koumallos N, Stefanadis C. Proinflammatory cytokines in acute coronary syndromes: from bench to bedside. Cytokine Growth Factor Rev 2006;17:225-33.20- Langer HF, Gawaz M. Platelet-vessel wall interactions in atherosclerotic disease. Thromb Haemost 2008; 99: 480–86
- 21- Proctor MJ, Morrison DS, Talwar D, Balmer SM, Fletcher CD, O'Reilly DS, et al. A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study. Eur J Cancer 2011;47:2633-41
- 22- Hao X, Li D, Wu D, Zhang N. The Relationship between Hematological Indices and Autoimmune Rheumatic Diseases (ARDs), a Meta-Analysis. Sci Rep. 2017; 7;7-1.
- 23- Uslu AU, Deveci K, Korkmaz S, Aydin B, Senel S, Sancakdar E et al. Is neutrophil/lymphocyte ratio associated with subclinical inflammation and amyloidosis in patients with familial Mediterranean fever? Biomed Res Int 2013;2013: 185317
- 24- Aktürk S, Büyükavcı R. Evaluation of blood neutrophil-lymphocyte ratio and platelet distribution width as inflammatory markers in patients with fibromyalgia. Clin Rheumatol 2017 36:1885–889
- 25- İlgün E, Akyürek Ö, Kalkan AO, Demir F, Demirayak M, Bilgi M. Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Fibromyalgia. Eur J Gen Med 2016;132:100-04
- 26- Montagnana M, Cervellin G, Meschi T, Lippi G. The role of red blood cell distribution width in cardiovascular and thrombotic disorders. Clin Chem Lab Med 2012;50:635-41
- 27- Kurtoğlu E, Aktürk E, Korkmaz H, Sincer I, Yılmaz M, Erdem K et al. Elevated red blood cell distribution width in healthy smokers. Turk Kardiyol Dern Ars. 2013 ;41:199-06
- 28- Uslu AU, Yonem O, Aydin B, Uncu T, Seven D, Balta S, et al. Red cell distribution width is associated with albuminuria in adults with familial Mediterranean fever. Kaohsiung J Med Sci. 2016;32:216-20
- 29- Alves B, Zakka TM, Teixeira MJ, Kaziyama HH, Siqueira JT, Siqueira SR. Depression, sexuality and fibromyalgia syndrome: clinical findings and correlation to hematological parameters. Arq Neuropsiquiatr. 2016 ;74:863-68
Evaluation of red blood cell distribution width,neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in patients with fibromyalgia
Abstract
Objective: In the present study we investigate the level of subclinical
inflammatory markers neutrophil to lymphocyte ratio (NLR), platelet to
lymphocyte ratio (PLR) and red blood cell distribution width (RDW) in FMS
Method: Included in the study were 98 patients who had been newly diagnosed with
FMS according to the 2010 American College of Rheumatology (ACR) criteria and
38 healthy controls. The age, Body Mass Index (BMI), White Blood Cell (WBC),
neutrophil, lymphocyte, platelet, high-sensitivity C-reactive protein (hsCRP)
and Erythrocyte Sedimentation Rate (ESR) values of the participants in both
groups were recorded, and also the Visual Analogue Scale (VAS) and Fibromyalgia
Impact Questionnaire (FIQ) scores of the patients
Results : There was no statistically significant difference
between Groups 1 and 2 with respect to NLR, PLR and RDW values (p>0.05).
Conclusions: Blood NLR, PLR and RDW values in patients with FMS
have no significance in an investigation of subclinical inflammation.
References
- 1- Theoharides TC, Tsilioni I, Arbetman L, Panagiotidou S, Stewart JM, Gleason RM, et al. Fibromyalgia syndrome in need of effective treatments. J Pharmacol Exp Ther 2015; 355: 255-63.
- 2- Dadabhoy D, Clauw DJ. Therapy insight: fibromyalgia a different type of pain needing a different type of treatment. Nat Clin Pract Rheumatol 2006;2:364-72.
- 3-Albrecht PJ, Rice FL Fibromyalgia syndrome pathology and environmental influences on afflictions with medically unexplained symptoms. Rev Environ Health. 2016; 1:281-94
- 4- Xiao Y, Haynes WL, Michalek JE, Russell IJ. Elevated serum high-sensitivity C-reactive protein levels in fibromyalgia syndrome patients correlate withbodymass index,interleukin-6, interleukin-8, erythrocyte sedimentation rate. Rheumatol Int 2013; 33: 1259–64.
- 5- Ozturk C, Balta S, Balta I, Demirkol S, Celik T, Turker T et al. NeutrophilLymphocyte Ratio and Carotid-Intima Media Thickness in Patients With Behcet Disease Without Cardiovascular Involvement. Angiology 2014; 66: 291-96
- 6- Hoffmann JJ, Nabbe KC, van den Broek NM. Effect of age and gender on reference intervals of red blood cell distribution width (RDW) and mean red cell volume (MCV). Clin Chem Lab Med 2015;53:2015-19
- 7- Lippi G, Targher G, Montagnana M, Salvagno GL, Zoppini G, Guidi GC. Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients. Arch Pathol Lab Med 2009;133:628-32. 8- Song CS, Park DI, Yoon MY, Seok HS, Park JH, Kim HJ et al. Association between red cell distribution width and disease activity in patients with inflammatory bowel disease. Dig Dis Sci 2012;57:1033-38.
- 9- Peng YF, Cao L, Zeng YH, Zhang ZX, Chen D, Zhang Q et al. Platelet to lymphocyte ratio and neutrophil to lymphocyte ratio in patients with rheumatoid arthritis. Open Med (Wars) 2015;10:249-53
- 10-Özer S, Yılmaz, Sönmezgöz E, Karaaslan E, Taşkın S, Bütün İ et al. Simple markers for subclinical inflammation in patients with Familial Mediterranean Fever. Med Sci Monit 2015;21:298-03
- 11- Bäckryd E, Tanum L, Lind AL, Larsson A, Gordh T. Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma. J Pain Res. 2017; 10: 515-25.
- 12- Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Katz RS, Mease P et al. The American Collage of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and Measurement of Symptom Severity. Arthritis Care & Research 2010; 62:600-10
- 13-Burckhardt CS, Clark SR, Bennett RM. The fibromyalgia impact questionnaire: development and validation. J Rheumatol 1991;18:728-33.
- 14- Sarmer S, Ergin S, Yavuzer G. The validity and reliability of the Turkish version of the Fibromyalgia Impact Questionnaire. Rheumatol Int 2000; 20:9-12. 15- Sayılır S. Remarkable Hematological Laboratory Findings in Patients with Fibromyalgia Syndrome. Turk J Osteoporos 2016; 22:121-4
- 16- Boyraz İ, Karakoyun A, Koç B. Determination presence of inflammation with neutrophil/lymphocyte and platelet /lymphocyte ratios in Fibromyalgia Syndrome. Eur J Health Sci 2015;1:15-917- Li J, Chen Q, Luo X, Hong J, Pan K, Lin X et al. Neutrophil-toLymphocyte Ratio Positively Correlates to Age in Healthy Population. J Clin Lab Anal 2015; 29: 437-4318- Imtiaz F, Shafique K, Mirza SS, Ayoob Z, Vart P, Rao S. Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population. Int Arch Med 2012;5:2. 19-Tousoulis D, Antoniades C, Koumallos N, Stefanadis C. Proinflammatory cytokines in acute coronary syndromes: from bench to bedside. Cytokine Growth Factor Rev 2006;17:225-33.20- Langer HF, Gawaz M. Platelet-vessel wall interactions in atherosclerotic disease. Thromb Haemost 2008; 99: 480–86
- 21- Proctor MJ, Morrison DS, Talwar D, Balmer SM, Fletcher CD, O'Reilly DS, et al. A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study. Eur J Cancer 2011;47:2633-41
- 22- Hao X, Li D, Wu D, Zhang N. The Relationship between Hematological Indices and Autoimmune Rheumatic Diseases (ARDs), a Meta-Analysis. Sci Rep. 2017; 7;7-1.
- 23- Uslu AU, Deveci K, Korkmaz S, Aydin B, Senel S, Sancakdar E et al. Is neutrophil/lymphocyte ratio associated with subclinical inflammation and amyloidosis in patients with familial Mediterranean fever? Biomed Res Int 2013;2013: 185317
- 24- Aktürk S, Büyükavcı R. Evaluation of blood neutrophil-lymphocyte ratio and platelet distribution width as inflammatory markers in patients with fibromyalgia. Clin Rheumatol 2017 36:1885–889
- 25- İlgün E, Akyürek Ö, Kalkan AO, Demir F, Demirayak M, Bilgi M. Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Fibromyalgia. Eur J Gen Med 2016;132:100-04
- 26- Montagnana M, Cervellin G, Meschi T, Lippi G. The role of red blood cell distribution width in cardiovascular and thrombotic disorders. Clin Chem Lab Med 2012;50:635-41
- 27- Kurtoğlu E, Aktürk E, Korkmaz H, Sincer I, Yılmaz M, Erdem K et al. Elevated red blood cell distribution width in healthy smokers. Turk Kardiyol Dern Ars. 2013 ;41:199-06
- 28- Uslu AU, Yonem O, Aydin B, Uncu T, Seven D, Balta S, et al. Red cell distribution width is associated with albuminuria in adults with familial Mediterranean fever. Kaohsiung J Med Sci. 2016;32:216-20
- 29- Alves B, Zakka TM, Teixeira MJ, Kaziyama HH, Siqueira JT, Siqueira SR. Depression, sexuality and fibromyalgia syndrome: clinical findings and correlation to hematological parameters. Arq Neuropsiquiatr. 2016 ;74:863-68
There are 23 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Medical Science Research Articles |
| Authors | |
| Publication Date | June 30, 2019 |
| Acceptance Date | May 23, 2019 |
| Published in Issue | Year 2019Volume: 41 Issue: 2 |