Evaluation of red blood cell distribution width,neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in patients with fibromyalgia
Abstract
Objective: In the present study we investigate the level of subclinical inflammatory markers neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and red blood cell distribution width (RDW) in FMS
Method: Included in the study were 98 patients who had been newly diagnosed with FMS according to the 2010 American College of Rheumatology (ACR) criteria and 38 healthy controls. The age, Body Mass Index (BMI), White Blood Cell (WBC), neutrophil, lymphocyte, platelet, high-sensitivity C-reactive protein (hsCRP) and Erythrocyte Sedimentation Rate (ESR) values of the participants in both groups were recorded, and also the Visual Analogue Scale (VAS) and Fibromyalgia Impact Questionnaire (FIQ) scores of the patients
Results : There was no statistically significant difference between Groups 1 and 2 with respect to NLR, PLR and RDW values (p>0.05).
Conclusions: Blood NLR, PLR and RDW values in patients with FMS have no significance in an investigation of subclinical inflammation.
Keywords
Kaynakça
- 1- Theoharides TC, Tsilioni I, Arbetman L, Panagiotidou S, Stewart JM, Gleason RM, et al. Fibromyalgia syndrome in need of effective treatments. J Pharmacol Exp Ther 2015; 355: 255-63.
- 2- Dadabhoy D, Clauw DJ. Therapy insight: fibromyalgia a different type of pain needing a different type of treatment. Nat Clin Pract Rheumatol 2006;2:364-72.
- 3-Albrecht PJ, Rice FL Fibromyalgia syndrome pathology and environmental influences on afflictions with medically unexplained symptoms. Rev Environ Health. 2016; 1:281-94
- 4- Xiao Y, Haynes WL, Michalek JE, Russell IJ. Elevated serum high-sensitivity C-reactive protein levels in fibromyalgia syndrome patients correlate withbodymass index,interleukin-6, interleukin-8, erythrocyte sedimentation rate. Rheumatol Int 2013; 33: 1259–64.
- 5- Ozturk C, Balta S, Balta I, Demirkol S, Celik T, Turker T et al. NeutrophilLymphocyte Ratio and Carotid-Intima Media Thickness in Patients With Behcet Disease Without Cardiovascular Involvement. Angiology 2014; 66: 291-96
- 6- Hoffmann JJ, Nabbe KC, van den Broek NM. Effect of age and gender on reference intervals of red blood cell distribution width (RDW) and mean red cell volume (MCV). Clin Chem Lab Med 2015;53:2015-19
- 7- Lippi G, Targher G, Montagnana M, Salvagno GL, Zoppini G, Guidi GC. Relation between red blood cell distribution width and inflammatory biomarkers in a large cohort of unselected outpatients. Arch Pathol Lab Med 2009;133:628-32. 8- Song CS, Park DI, Yoon MY, Seok HS, Park JH, Kim HJ et al. Association between red cell distribution width and disease activity in patients with inflammatory bowel disease. Dig Dis Sci 2012;57:1033-38.
- 9- Peng YF, Cao L, Zeng YH, Zhang ZX, Chen D, Zhang Q et al. Platelet to lymphocyte ratio and neutrophil to lymphocyte ratio in patients with rheumatoid arthritis. Open Med (Wars) 2015;10:249-53
Ayrıntılar
Birincil Dil
İngilizce
Konular
Sağlık Kurumları Yönetimi
Bölüm
Araştırma Makalesi
Yayımlanma Tarihi
30 Haziran 2019
Gönderilme Tarihi
4 Aralık 2018
Kabul Tarihi
23 Mayıs 2019
Yayımlandığı Sayı
Yıl 1970 Cilt: 41 Sayı: 2