Research Article
Year 2019,
Volume: 41 Issue: 3, 647 - 652, 30.09.2019
Abstract
References
- 1. Kinlay JR, O’Connell DL, Kinlay S. Incidence of mastitis in breastfeeding women during the six months after delivery: A prospective cohort study. Med J Aust. 1998;169(6):310–12.
- 2. Vogel A, Hutchison BL, Mitchell EA. Mastitis in the first year postpartum. Birth. 1999;26(4):218–25.
- 3. Fetherston C. Mastitis in lactating women: physiology or pathology? Breastfeed Rev. 2001;9(1):5–12.
- 4. Amir LH. ABM clinical protocol #4: Mastitis, revised in March 2014. Breastfeed Med. 2014;9(5):239–43.
- 5. Bolman M, Saju L, Oganesyan K, et al. Recapturing the art of therapeutic breast massage during breastfeeding. J Hum Lact. 2013;29(3):328–31.
- 6. Thomsen AC, Espersen T, Maigaard S. Course and treatment of milk stasis, noninfectious inflammation of the breast, and infectious mastitis in nursing women. Am J Obstet Gynecol. 1984;149(5):492–95.
- 7. Dener C, Inan A. Breast abscesses in lactating women. World J Surg. 2003;27(2):130–133.
- 8. Berens PD. Prenatal, intrapartum, and postpartum support of the lactating mother. Pediatr Clin North Am. 2001;48(2):365–375.
- 9. Witt AM, Bolman M, Kredit S, Vanic A. Therapeutic breast massage in lactation for the management of engorgement, plugged ducts, and mastitis. J Hum Lact. 2016;32(1):123–31.
- 10. Ioffe IV, Chernova NV. [Efficacy of surgical treatment of patients for acute lactational mastitis using a radiofrequency scalpel and ozone-ultrasonic method]. Klin Khir. 2013;(1):65–68. [in Russian]
- 11. Feijen-de Jong EI, Baarveld F, Jansen DE, et al. Do pregnant women contact their general practitioner? A register-based comparison of healthcare utilization of pregnant and non-pregnant women in general practice. BMC Fam Pract. 2013;14:10.
- 12. Amir LH, Trupin S, Kvist LJ. Diagnosis and treatment of mastitis in breastfeeding women. J Hum Lact. 2014;30(1):10–13.
- 13. Reddy PN, Srirama K, Dirisala VR. An Update on Clinical Burden, Diagnostic Tools, and Therapeutic Options of Staphylococcus aureus. Infect Dis (Auckl). 2017;10:1179916117703999.
- 14. Meguid MM, Oler A, Numann PJ, Khan S: Pathogenesis-based treatment of recurring subareolar breast abscesses. Surgery 1955; 118:775–782.
- 15.Dixon JM: Outpatient treatment of non-lactational breast abscesses. Br J Surg 1992;79: 56–57.
- 16. Walker AP, Edmiston CE Jr, Krepel CJ, Con- don RE: A prospective study of the microflora of non-puerperal breast abscess. Arch Surg 1988;123:908–911
- 17. Brook L: Microbiology of non-puerperal breast abscesses. J Infect Dis 1988;157:377– 379.
- 18. Lawrence RA, Lawrence RM. Management of the mother-infant nursing couple. In: Breastfeeding: A Guide for the Medical Profession. 6th ed. St. Louis, Mo.: Mosby; 2005:255–316.
- 19. Wambach KA. Lactation mastitis: a descriptive study of the experience. J Hum Lact. 2003;19(1):24–34.
- 20. Osterman KL, Rahm VA. Lactation mastitis: bacterial cultivation of breast milk, symptoms, treatment, and outcome. J Hum Lact. 2000;16(4):297–302.
- 21. Department of Child and Adolescent Health and Development. Mastitis: causes and management. Geneva, Switzerland: World Health Organization; 2000. http://whqlibdoc.who.int/hq/2000/WHO_FCH_CAH_00.13.pdf. Accessed June 15, 2008.
- 22. Moazzez A, Rebecca L, Kelso RL, et al. Breast abscess bacteriologic features in the era of community-acquired methicillin- resistant Staphylococcus aureus epidemics. Arch Surg 2007;142:881–884.
- 23. Prachniak GK. Common breastfeeding problems. Obstet Gynecol Clin North Am. 2002;29(1):77-88
Intravenous ceftriaxone plus clindamycin reduces breast abscess formation in severe lactational mastitis
Abstract
Objective: Lactational mastitis can
progress to local abscess formation if not treated promptly. The study aims to understand whether the
use of intravenous cephalosporin plus clindamycin could reduce breast abscess
formation when preferred as a first-line treatment instead of oral penicillin.
Method: Patients who admitted to our
outpatient clinic with sign and symptoms of lactational mastitis were recruited
retrospectively for the study. Patients who had abscess formation on admittance
were excluded. Patients were categorized into two groups according to
antibiotic preference as the group I with intravenous ceftriaxone plus
clindamycin and group II with oral penicillin. Groups were compared according
to abscess formation in follow-up by physical examination and ultrasound.
Results: A
total of 64 patients with severe lactational mastitis were included. In group I
(n=29), only one breast abscess with MSSA was developed. However, seven cases
of breast abscess were developed in the second group (n=35). MRSA (n=4), MSSA
(n=1), gram-negative bacilli (n=1) and no organism (n=1) were cultured in pus
among group II. The prevalence of abscess in group I is found to be
significantly lower in comparison to the control group in 12 weeks follow-up
(p=0.049).
Conclusions: MRSA
and gr (-) bacilli are the significant agents in persistent breast abscess
formation, which are resistant to oral penicillin or first/second-line
cephalosporin. The ceftriaxone plus clindamycin could be used to reduce abscess
formation after severe lactational mastitis, therefore, avoids unnecessary
operations and hospitalization.
References
- 1. Kinlay JR, O’Connell DL, Kinlay S. Incidence of mastitis in breastfeeding women during the six months after delivery: A prospective cohort study. Med J Aust. 1998;169(6):310–12.
- 2. Vogel A, Hutchison BL, Mitchell EA. Mastitis in the first year postpartum. Birth. 1999;26(4):218–25.
- 3. Fetherston C. Mastitis in lactating women: physiology or pathology? Breastfeed Rev. 2001;9(1):5–12.
- 4. Amir LH. ABM clinical protocol #4: Mastitis, revised in March 2014. Breastfeed Med. 2014;9(5):239–43.
- 5. Bolman M, Saju L, Oganesyan K, et al. Recapturing the art of therapeutic breast massage during breastfeeding. J Hum Lact. 2013;29(3):328–31.
- 6. Thomsen AC, Espersen T, Maigaard S. Course and treatment of milk stasis, noninfectious inflammation of the breast, and infectious mastitis in nursing women. Am J Obstet Gynecol. 1984;149(5):492–95.
- 7. Dener C, Inan A. Breast abscesses in lactating women. World J Surg. 2003;27(2):130–133.
- 8. Berens PD. Prenatal, intrapartum, and postpartum support of the lactating mother. Pediatr Clin North Am. 2001;48(2):365–375.
- 9. Witt AM, Bolman M, Kredit S, Vanic A. Therapeutic breast massage in lactation for the management of engorgement, plugged ducts, and mastitis. J Hum Lact. 2016;32(1):123–31.
- 10. Ioffe IV, Chernova NV. [Efficacy of surgical treatment of patients for acute lactational mastitis using a radiofrequency scalpel and ozone-ultrasonic method]. Klin Khir. 2013;(1):65–68. [in Russian]
- 11. Feijen-de Jong EI, Baarveld F, Jansen DE, et al. Do pregnant women contact their general practitioner? A register-based comparison of healthcare utilization of pregnant and non-pregnant women in general practice. BMC Fam Pract. 2013;14:10.
- 12. Amir LH, Trupin S, Kvist LJ. Diagnosis and treatment of mastitis in breastfeeding women. J Hum Lact. 2014;30(1):10–13.
- 13. Reddy PN, Srirama K, Dirisala VR. An Update on Clinical Burden, Diagnostic Tools, and Therapeutic Options of Staphylococcus aureus. Infect Dis (Auckl). 2017;10:1179916117703999.
- 14. Meguid MM, Oler A, Numann PJ, Khan S: Pathogenesis-based treatment of recurring subareolar breast abscesses. Surgery 1955; 118:775–782.
- 15.Dixon JM: Outpatient treatment of non-lactational breast abscesses. Br J Surg 1992;79: 56–57.
- 16. Walker AP, Edmiston CE Jr, Krepel CJ, Con- don RE: A prospective study of the microflora of non-puerperal breast abscess. Arch Surg 1988;123:908–911
- 17. Brook L: Microbiology of non-puerperal breast abscesses. J Infect Dis 1988;157:377– 379.
- 18. Lawrence RA, Lawrence RM. Management of the mother-infant nursing couple. In: Breastfeeding: A Guide for the Medical Profession. 6th ed. St. Louis, Mo.: Mosby; 2005:255–316.
- 19. Wambach KA. Lactation mastitis: a descriptive study of the experience. J Hum Lact. 2003;19(1):24–34.
- 20. Osterman KL, Rahm VA. Lactation mastitis: bacterial cultivation of breast milk, symptoms, treatment, and outcome. J Hum Lact. 2000;16(4):297–302.
- 21. Department of Child and Adolescent Health and Development. Mastitis: causes and management. Geneva, Switzerland: World Health Organization; 2000. http://whqlibdoc.who.int/hq/2000/WHO_FCH_CAH_00.13.pdf. Accessed June 15, 2008.
- 22. Moazzez A, Rebecca L, Kelso RL, et al. Breast abscess bacteriologic features in the era of community-acquired methicillin- resistant Staphylococcus aureus epidemics. Arch Surg 2007;142:881–884.
- 23. Prachniak GK. Common breastfeeding problems. Obstet Gynecol Clin North Am. 2002;29(1):77-88
There are 23 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Surgical Science Research Articles |
| Authors | |
| Publication Date | September 30, 2019 |
| Acceptance Date | September 25, 2019 |
| Published in Issue | Year 2019Volume: 41 Issue: 3 |