Abstract
References
- Vanderpump MP The Epidemiology of Thyroid Disease. Br Med Bull (2011).99:39-51.
- Ze Rial M, Mcbride H. Rab Proteins as Membrane Organizers. Nat Rev Mol Cell Biol (2001). 2: 107-117.
- Erdoğan MF, Kamel N, Aras D, Akdoğan A, Başkal N, Erdoğan G. Value of Re-aspira Benign Nodular Thyroid Disease. Thyroid (1998).8:1087-90.
- Bernards A, Settlema NJ. GAP Control: Regulating the Regulators of Small GTPases. Trends Cell Biol (2004). 14: 377-385.
- Zhang JS, Yang LQ, Du Br, Gao H. Higher RABEX-5 mRNA Predicts Unfavourable Survival in Patients with Colorectal Cancer. Eur Rev Med Pharmacol Sci. (2017). 21(10):2372-2376.
- Kang l, Hao X, Tang Y, Wei X, Gong Y. RABEX-5 Overexpression in Gastric Cancer is Correlated with Elevated MMP-9 level. Am J Transl Res (2006). 8: 2365-2374.
- Zhang F, Jia Y, Kong F, Hu G, Cai Q, Xu T. Elevated RABEX-5 Expression Predicts Poor Prognosis in Non-Small-Cell Lung Cancer. Am J Cancer Res (20015). 5: 2849-2855.
Assessment of rabex-5 level of thyroid nodules with benign and malignant characteristics in aspiration cytology
Abstract
Objective: The aim of the present study was to determine the
Rabex-5 level in the plasma of patients who were found to have benign and
malignant cytology as a result of fine-needle aspiration biopsy implemented on
thyroid nodules and to determine whether there was a difference between benign
and malignant.
Method: The cytology of 117 benign and 26 malignant thyroid
nodules was evaluated as the study material.
Results: It was determined that the nodule diameter had no
effect on benign and malignant cytology (p 0.998). There was no significant
difference found between age and benign and malignant cytology results (p
0.591). There was no difference between female and male genders in terms of
Rabex-5 level (p 0.654).
Conclusions: In conclusion, it was found that there was no difference in plasma
RABEX-5 levels of patients with benign and malignant thyroid nodule cytology.
However, it is thought that further studies to evaluate the expression of
Rabex-5 in cancerous tissues of patients with thyroid malignancies will provide
a scientific contribution
References
- Vanderpump MP The Epidemiology of Thyroid Disease. Br Med Bull (2011).99:39-51.
- Ze Rial M, Mcbride H. Rab Proteins as Membrane Organizers. Nat Rev Mol Cell Biol (2001). 2: 107-117.
- Erdoğan MF, Kamel N, Aras D, Akdoğan A, Başkal N, Erdoğan G. Value of Re-aspira Benign Nodular Thyroid Disease. Thyroid (1998).8:1087-90.
- Bernards A, Settlema NJ. GAP Control: Regulating the Regulators of Small GTPases. Trends Cell Biol (2004). 14: 377-385.
- Zhang JS, Yang LQ, Du Br, Gao H. Higher RABEX-5 mRNA Predicts Unfavourable Survival in Patients with Colorectal Cancer. Eur Rev Med Pharmacol Sci. (2017). 21(10):2372-2376.
- Kang l, Hao X, Tang Y, Wei X, Gong Y. RABEX-5 Overexpression in Gastric Cancer is Correlated with Elevated MMP-9 level. Am J Transl Res (2006). 8: 2365-2374.
- Zhang F, Jia Y, Kong F, Hu G, Cai Q, Xu T. Elevated RABEX-5 Expression Predicts Poor Prognosis in Non-Small-Cell Lung Cancer. Am J Cancer Res (20015). 5: 2849-2855.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Medical Science Research Articles |
| Authors | |
| Publication Date | December 31, 2019 |
| Acceptance Date | December 31, 2019 |
| Published in Issue | Year 2019Volume: 41 Issue: 4 |