Research Article
Year 2021,
Volume: 43 Issue: 1, 31 - 40, 31.03.2021
Abstract
References
- [1]. Khan RBDL. Brain metastases. In: Schiff DWP, editor. Cancer neurology in clinical practice. Totawa, NJ, USA: Humana Press; 2003 [2]. Radbruch A, Graf M, Kramp L, Wiestler B, Floca R, Bäumer P, et al. Differentiation of brain metastases by percentagewise quantification of intratumoral susceptibility signals at 3Tesla. Eur J Radiol. 2012 Dec; 81(12):4064–8. [PubMed: 22795527]
Assessment of hemorrhage and paramagnetic substance accumulation in brain metastases by susceptibility weighted imaging
Abstract
Objective: We aimed to make a differential diagnosis of brain metastases by using the percentage of the ITSS by the SWI sequence.
Method: MR images of 77 patients with intracerebral metastases were evaluated in this study who had breast carcinoma (BC)(n=23), malignant melanoma (MM)(n=4), lung cancer (LC) (n=42), and gastrointestinal adenocancer (GIA)(n=8) as the primary tumor. We calculated the ratio of the ITSS pixels.
Results: ITSS percentages of metastases were found 22.52% in LC, 47.61% in GIA, 11.85% in BC, and 60.75% in MM. In terms of differential diagnosis of the ITSS percentages measured in the SWI sequence, the diagnostic performance was very good between MM-BC, good between MM-LC, GIA-LC, and GIA-BC, and poor between LC-BC and GIA-MM. Percentages of ITSS had high sensitivity and specificity to make a differential diagnosis between GIA-LC, GIA-BC, MM-BC, and MM-LC.
Conclusions: We conclude that measuring the ITSS percentage values of metastases when evaluating brain masses by MRI will provide valuable additional information for differential diagnosis.
References
- [1]. Khan RBDL. Brain metastases. In: Schiff DWP, editor. Cancer neurology in clinical practice. Totawa, NJ, USA: Humana Press; 2003 [2]. Radbruch A, Graf M, Kramp L, Wiestler B, Floca R, Bäumer P, et al. Differentiation of brain metastases by percentagewise quantification of intratumoral susceptibility signals at 3Tesla. Eur J Radiol. 2012 Dec; 81(12):4064–8. [PubMed: 22795527]
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Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Medical Science Research Articles |
| Authors | |
| Publication Date | March 31, 2021 |
| Acceptance Date | March 31, 2021 |
| Published in Issue | Year 2021Volume: 43 Issue: 1 |