Abstract
References
- REFERENCES 1. Chan CK, Lam HC, Chiu SW, Tse ML, Lau FL. Mushroom poisoning in Hong Kong: a ten-year review. Hong Kong Med J 2016; 22(2): 124-130.
- 2. Kintziger KW, Mulay P, Watkins S, Kintziger KW, Mulay P, Watkins S, et al. Wild mushroom exposures in Florida, 2003-2007. Public Health Rep. 2011;126(6):844-852. 3. Schneider SM, Mushrooms. In: Ford MD, Delaney KA, Ling LJ, Erickson T, editors, Philadelphia, PA: Saunders Company. Clinical Toxicology 2001: 899–909.
- 4. Cervellin G, Comelli I, Rastelli G, Sanchis-Gomar F, F Negri, Luca C De, et al., Epidemiology and clinics of mushroom poisoning in Northern Italy: A 21-year retrospective analysis. Hum Exp Toxicol 2018; 37(7): 697-703.
- 5. Barbee G, Berry-Cabán C, Barry J, Borys D, Ward J, Salyer S. Analysis of mushroom exposures in Texas requiring hospitalization, 2005-2006. J Med Toxicol 2009; 5(2): 59-62.
- 6. Schmutz M, Carron PN, Yersin B, Trueb L. Mushroom poisoning: a retrospective study concerning 11-years of admissions in a Swiss Emergency Department. Intern Emerg Med 2018; 13(1):59-67
- 7. Saviuc P, Flesch F, Acute higher funghi mushroom poisoning and its treatment. Presse Med 2003; 32(30):1427-1435.
- 8. Diaz JH. Syndromic diagnosis and management of confirmed mushroom poisonings. Crit Care Med 2005; 33(2): 427-436.
- 9. Erden A, Esmeray K, Karagöz H, Karahan S, Gümüşçü HH, Başak M, et al. Acute liver failure caused by mushroom poisoning: a case report and review of the literature. Int Med Case Rep. J 2013; 22(6): 85-90.
- 10. Ward J, Kapadia K, Brush E, Salhanick SD. Amatoxin poisoning: case reports and review of current therapies. J Emerg Med 2013; 44(1): 116-121.
- 11. McClintock RL, Watts DJ, Melanson S. Unrecognized magic mushroom abuse in a 28-year-old man. Am J Emerg Med 2008; 26(8): 972.e3-4.
- 12. Eren SH, Demirel Y, Ugurlu S, Korkmaz I, Aktas C, Güven FM. Mushroom poisoning: retrospective analysis of 294 cases. Clinics (Sao Paulo). 2010; 65(5) :491-496.
- 13. Comelli I, Lippi G, De Blasio A, Cervellin G. Accidental mushroom poisoning mimicking stroke. A case report and literature review. Acta Biomed 2014; 84(3) :229-33.
- 14. Goldfrank LR. Mushrooms. In: Hoffman RS, Howland MA, Levin NA, Nelson LS, Goldfrank LR editors. Goldfrank’s Toxicologic Emergencies 10th Edition. New York: McGraw-Hill Education 2015; 2546–2570.
- 15. Hsu CW. Glycemic control in critically ill patients. World J Crit Care Med 2012; 1(1): 31-39.
- 16. Pérez-Calatayud ÁA, Guillén-Vidaña A, Fraire-Félix IS, Anica-Malagón ED, Briones Garduño JC, Carrillo-Esper R. Metabolic control in the critically ill patient an update: hyperglycemia, glucose variability hypoglycemia and relative hypoglycemia. Cir Cir 2017; 85(1): 93-100.
- 17. Van den Berghe G. How does blood glucose control withinsulin save lives in intensive care. J Clin Invest. 2004; 114(9): 1187-1195.
- 18. Bonacini M, Shetler K, Yu I, Osorio RC, Osorio RW. Features of Patients With Severe Hepatitis Due to Mushroom Poisoning and Factors Associated With Outcome. Clin Gastroenterol Hepatol 2017; 15(5): 776-779.
- 19. Jan MA, Siddiqui TS, Ahmed N, UI Haq I, Khan Z. Mushroom poisoning in children: clinical presentation and outcome. J Ayub Med Coll Abbottabad 2008; 20(2): 99-101.
- 20. Ganzert M, Felgenhauer N, Zilker T. Indication of liver transplantation following amatoxin intoxication. J Hepatol 2005; 42(2): 202-209.
- 21. Tongyoo S, Viarasilpa T, Permpikul C. Serum potassium levels and outcomes in critically ill patients in the medical intensive care unit. J Int Med Res 2018; 46(3): 1254–1262.
- 22. Xi H, Yu RH, Wang N, Chen XZ, Zhang WC, Hong T. Hong, Serum potassium levels and mortality of patients with acute myocardial infarction: A systematic review and meta-analysis of cohort studies. Eur J Prev Cardiol. 2019; 26(2):145-156.
- 23. Goyal A, Spertus JA, Gosch K, Venkitachalamet L, Jones PG, Van den Berghe G, et al. Serum potassium levels and mortality in acute myocardial infarction. JAMA. 2012; 307(2):157-164.
- 24. Matano F, Fujiki Y, Mizunari T, et.al. Serum Glucose and Potassium Ratio as Risk Factors for Cerebral Vasospasmafter Aneurysmal Subarachnoid Hemorrhage. J Stroke Cerebrovasc Dis. 2019;28:1951-1957.
Correlation Between Serum Glucose/Potassium Ratio and The Severity of Mushroom Poisoning at The Time of Admission to The Emergency Departments
Abstract
Exposure to wild mushrooms can lead to serious toxicity and death. It is accepted that patients who ingest potentially lethal mushrooms typically develop toxicity signs after six hours. However, clinical manifestations of poisoning that occur less than six hours after ingestion do not exclude the potential for life-threatening toxicity, especially when more than one type of mushroom has been eaten. Whereas there are not any clinical parameters that help to establish the severity of mushroom poisoning. In this study, we aimed to determine the relationship of serum glucose/potassium ratio and the clinical severity of mushroom poisoning cases.This is a retrospective study which includes the mushroom poisoning 510 cases between the years 2007 - 2018. Data consisted of age, gender, clinical history of mushroom poisoning including time from consumption to first symptoms, date of presentation, discharge time and laboratory results including complete blood cell count, biochemistry tests for liver and renal function, and coagulation profile. Patients included in this study were classified as mild-moderate and severe mushroom poisoning groups according to laboratory and clinical characteristics. Glucose, BUN, Creatinine, ALT, AST mean values and glucose/potassium ratio were significantly higher in the clinically severe group patients (p=0.008, p=0.01, p=0.039, p=0.037, p=0.046 and p=0.036 respectively). The sensitivity, specificity and area under curve for glucose/potassium ratio were as follows; 0.68, 0.57 (AUC %95CI) was 0.0647. Glucose/potassium ratio can predict the severity in mushroom poisonings according to our results which can helpful by management in mushroom poisonings as a laboratory result.
Keywords
Mushroom poisoning Glucose/potassium ratio Emergency department Mushroom poisoning, Glucose/potassium ratio, Emergency department
References
- REFERENCES 1. Chan CK, Lam HC, Chiu SW, Tse ML, Lau FL. Mushroom poisoning in Hong Kong: a ten-year review. Hong Kong Med J 2016; 22(2): 124-130.
- 2. Kintziger KW, Mulay P, Watkins S, Kintziger KW, Mulay P, Watkins S, et al. Wild mushroom exposures in Florida, 2003-2007. Public Health Rep. 2011;126(6):844-852. 3. Schneider SM, Mushrooms. In: Ford MD, Delaney KA, Ling LJ, Erickson T, editors, Philadelphia, PA: Saunders Company. Clinical Toxicology 2001: 899–909.
- 4. Cervellin G, Comelli I, Rastelli G, Sanchis-Gomar F, F Negri, Luca C De, et al., Epidemiology and clinics of mushroom poisoning in Northern Italy: A 21-year retrospective analysis. Hum Exp Toxicol 2018; 37(7): 697-703.
- 5. Barbee G, Berry-Cabán C, Barry J, Borys D, Ward J, Salyer S. Analysis of mushroom exposures in Texas requiring hospitalization, 2005-2006. J Med Toxicol 2009; 5(2): 59-62.
- 6. Schmutz M, Carron PN, Yersin B, Trueb L. Mushroom poisoning: a retrospective study concerning 11-years of admissions in a Swiss Emergency Department. Intern Emerg Med 2018; 13(1):59-67
- 7. Saviuc P, Flesch F, Acute higher funghi mushroom poisoning and its treatment. Presse Med 2003; 32(30):1427-1435.
- 8. Diaz JH. Syndromic diagnosis and management of confirmed mushroom poisonings. Crit Care Med 2005; 33(2): 427-436.
- 9. Erden A, Esmeray K, Karagöz H, Karahan S, Gümüşçü HH, Başak M, et al. Acute liver failure caused by mushroom poisoning: a case report and review of the literature. Int Med Case Rep. J 2013; 22(6): 85-90.
- 10. Ward J, Kapadia K, Brush E, Salhanick SD. Amatoxin poisoning: case reports and review of current therapies. J Emerg Med 2013; 44(1): 116-121.
- 11. McClintock RL, Watts DJ, Melanson S. Unrecognized magic mushroom abuse in a 28-year-old man. Am J Emerg Med 2008; 26(8): 972.e3-4.
- 12. Eren SH, Demirel Y, Ugurlu S, Korkmaz I, Aktas C, Güven FM. Mushroom poisoning: retrospective analysis of 294 cases. Clinics (Sao Paulo). 2010; 65(5) :491-496.
- 13. Comelli I, Lippi G, De Blasio A, Cervellin G. Accidental mushroom poisoning mimicking stroke. A case report and literature review. Acta Biomed 2014; 84(3) :229-33.
- 14. Goldfrank LR. Mushrooms. In: Hoffman RS, Howland MA, Levin NA, Nelson LS, Goldfrank LR editors. Goldfrank’s Toxicologic Emergencies 10th Edition. New York: McGraw-Hill Education 2015; 2546–2570.
- 15. Hsu CW. Glycemic control in critically ill patients. World J Crit Care Med 2012; 1(1): 31-39.
- 16. Pérez-Calatayud ÁA, Guillén-Vidaña A, Fraire-Félix IS, Anica-Malagón ED, Briones Garduño JC, Carrillo-Esper R. Metabolic control in the critically ill patient an update: hyperglycemia, glucose variability hypoglycemia and relative hypoglycemia. Cir Cir 2017; 85(1): 93-100.
- 17. Van den Berghe G. How does blood glucose control withinsulin save lives in intensive care. J Clin Invest. 2004; 114(9): 1187-1195.
- 18. Bonacini M, Shetler K, Yu I, Osorio RC, Osorio RW. Features of Patients With Severe Hepatitis Due to Mushroom Poisoning and Factors Associated With Outcome. Clin Gastroenterol Hepatol 2017; 15(5): 776-779.
- 19. Jan MA, Siddiqui TS, Ahmed N, UI Haq I, Khan Z. Mushroom poisoning in children: clinical presentation and outcome. J Ayub Med Coll Abbottabad 2008; 20(2): 99-101.
- 20. Ganzert M, Felgenhauer N, Zilker T. Indication of liver transplantation following amatoxin intoxication. J Hepatol 2005; 42(2): 202-209.
- 21. Tongyoo S, Viarasilpa T, Permpikul C. Serum potassium levels and outcomes in critically ill patients in the medical intensive care unit. J Int Med Res 2018; 46(3): 1254–1262.
- 22. Xi H, Yu RH, Wang N, Chen XZ, Zhang WC, Hong T. Hong, Serum potassium levels and mortality of patients with acute myocardial infarction: A systematic review and meta-analysis of cohort studies. Eur J Prev Cardiol. 2019; 26(2):145-156.
- 23. Goyal A, Spertus JA, Gosch K, Venkitachalamet L, Jones PG, Van den Berghe G, et al. Serum potassium levels and mortality in acute myocardial infarction. JAMA. 2012; 307(2):157-164.
- 24. Matano F, Fujiki Y, Mizunari T, et.al. Serum Glucose and Potassium Ratio as Risk Factors for Cerebral Vasospasmafter Aneurysmal Subarachnoid Hemorrhage. J Stroke Cerebrovasc Dis. 2019;28:1951-1957.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Surgical Science Research Articles |
| Authors | |
| Publication Date | March 30, 2022 |
| Acceptance Date | March 25, 2022 |
| Published in Issue | Year 2022Volume: 44 Issue: 1 |