Araştırma Makalesi

Correlation Between Serum Glucose/Potassium Ratio and The Severity of Mushroom Poisoning at The Time of Admission to The Emergency Departments

Cilt: 44 Sayı: 1 30 Mart 2022
Cumhuriyet Tıp Dergisi Kapak
Cumhuriyet Tıp Dergisi
PDF İndir
EN

Correlation Between Serum Glucose/Potassium Ratio and The Severity of Mushroom Poisoning at The Time of Admission to The Emergency Departments

Abstract

Exposure to wild mushrooms can lead to serious toxicity and death. It is accepted that patients who ingest potentially lethal mushrooms typically develop toxicity signs after six hours. However, clinical manifestations of poisoning that occur less than six hours after ingestion do not exclude the potential for life-threatening toxicity, especially when more than one type of mushroom has been eaten. Whereas there are not any clinical parameters that help to establish the severity of mushroom poisoning. In this study, we aimed to determine the relationship of serum glucose/potassium ratio and the clinical severity of mushroom poisoning cases.This is a retrospective study which includes the mushroom poisoning 510 cases between the years 2007 - 2018. Data consisted of age, gender, clinical history of mushroom poisoning including time from consumption to first symptoms, date of presentation, discharge time and laboratory results including complete blood cell count, biochemistry tests for liver and renal function, and coagulation profile. Patients included in this study were classified as mild-moderate and severe mushroom poisoning groups according to laboratory and clinical characteristics. Glucose, BUN, Creatinine, ALT, AST mean values and glucose/potassium ratio were significantly higher in the clinically severe group patients (p=0.008, p=0.01, p=0.039, p=0.037, p=0.046 and p=0.036 respectively). The sensitivity, specificity and area under curve for glucose/potassium ratio were as follows; 0.68, 0.57 (AUC %95CI) was 0.0647. Glucose/potassium ratio can predict the severity in mushroom poisonings according to our results which can helpful by management in mushroom poisonings as a laboratory result.

Keywords

Kaynakça

  1. REFERENCES 1. Chan CK, Lam HC, Chiu SW, Tse ML, Lau FL. Mushroom poisoning in Hong Kong: a ten-year review. Hong Kong Med J 2016; 22(2): 124-130.
  2. 2. Kintziger KW, Mulay P, Watkins S, Kintziger KW, Mulay P, Watkins S, et al. Wild mushroom exposures in Florida, 2003-2007. Public Health Rep. 2011;126(6):844-852. 3. Schneider SM, Mushrooms. In: Ford MD, Delaney KA, Ling LJ, Erickson T, editors, Philadelphia, PA: Saunders Company. Clinical Toxicology 2001: 899–909.
  3. 4. Cervellin G, Comelli I, Rastelli G, Sanchis-Gomar F, F Negri, Luca C De, et al., Epidemiology and clinics of mushroom poisoning in Northern Italy: A 21-year retrospective analysis. Hum Exp Toxicol 2018; 37(7): 697-703.
  4. 5. Barbee G, Berry-Cabán C, Barry J, Borys D, Ward J, Salyer S. Analysis of mushroom exposures in Texas requiring hospitalization, 2005-2006. J Med Toxicol 2009; 5(2): 59-62.
  5. 6. Schmutz M, Carron PN, Yersin B, Trueb L. Mushroom poisoning: a retrospective study concerning 11-years of admissions in a Swiss Emergency Department. Intern Emerg Med 2018; 13(1):59-67
  6. 7. Saviuc P, Flesch F, Acute higher funghi mushroom poisoning and its treatment. Presse Med 2003; 32(30):1427-1435.
  7. 8. Diaz JH. Syndromic diagnosis and management of confirmed mushroom poisonings. Crit Care Med 2005; 33(2): 427-436.
  8. 9. Erden A, Esmeray K, Karagöz H, Karahan S, Gümüşçü HH, Başak M, et al. Acute liver failure caused by mushroom poisoning: a case report and review of the literature. Int Med Case Rep. J 2013; 22(6): 85-90.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Yayımlanma Tarihi

30 Mart 2022

Gönderilme Tarihi

4 Şubat 2022

Kabul Tarihi

25 Mart 2022

Yayımlandığı Sayı

Yıl 2022 Cilt: 44 Sayı: 1

DOI

https://doi.org/10.7197/cmj.1068418

IZ

https://izlik.org/JA92FR73JT

Kaynak Göster

RIS / Bibtex
AMA
1.Tekin Y, Demirtaş E, Korkmaz İ, Demirel Y, Tekin G, Nur N. Correlation Between Serum Glucose/Potassium Ratio and The Severity of Mushroom Poisoning at The Time of Admission to The Emergency Departments. CMJ. 2022;44(1):104-109. doi:10.7197/cmj.1068418