Objectives: This study aimed to investigate the effects of non-alcoholic fatty liver disease on thyroid nodule prevalence
Methods: A total of 384 patients who were followed up with Grade 2-3 Non-Alcoholic Fatty Liver diagnosis were investigated for the presence of multinodular and/or nodular goiter. Demographic characteristics, biochemical data, and abdominal and thyroid ultrasonography reports of the patients were collected from patient files and electronic records.
Results: The ALT (cut-off level 10-40 U/L), GGT (cut-level 0 - 65 U / L), triglyceride (0-150 mg/dL), homeostasis model assessment of insulin resistance (HOMA-IR index value < 2.71), and TSH (cut-off level 0.45-4.12 mU / L), which are biochemical and metabolic parameters examined in our study, increased at statistically significant levels as the fat increased in the liver. A total of 45.8% (176/384) of the patients had Grade-2 Non-Alcoholic Fatty Liver Disease, and 54.1% (208/384) had Grade-3 Non-Alcoholic Fatty Liver Disease. As fat increased in the Non-Alcoholic Fatty Liver Disease, the prevalence of nodules increased at statistically significant levels (p=0.001).
Conclusion: Our study found that the frequency of thyroid nodules, disruption of the parenchymal structure, and metabolic and biochemical disruption are parallel in non-Alcoholic fatty liver patients.
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Primary Language | English |
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Subjects | Health Care Administration |
Journal Section | Medical Science Research Articles |
Authors | |
Project Number | None |
Publication Date | December 31, 2022 |
Acceptance Date | December 29, 2022 |
Published in Issue | Year 2022Volume: 44 Issue: 4 |