Objectives: For optimal histomorphological examination, adequacy of kidney biopsy tissue
should be obtained. In this study, the effect of a pathologist informing the radiologist about
tissue adequacy during the biopsy procedure on obtaining tissue adequacy was examined.
Furthermore, we aimed to determine the criteria that the pathologist considered in determining
tissue adequacy and the conditions affecting the decision to increase the number of core
biopsies, as these have not been previously examined in the literature.
Materials and Methods: Tissues containing less than 10 glomeruli were considered
inadequate. In some patients, a pathologist accompanied the radiologist during the procedure.
Tissue adequacy ratios and biopsy sample numbers were calculated between the two
conditions. In the samples taken with the pathologist, the factors affecting the locality
decision of the pathologist (cortex/medulla amount, presence of glomerular pathology(global,
segmental, crescentic glomeruli) presence of tubular injury, proteinuria; interstitial
inflammation and interstitial fibrosis/tubular atrophy ratios, account of normal glomeruli)
were examined.
Results: Giving tissue adequacy information during the biopsy procedure had a positive
effect on tissue adequacy. The amount of cortex is one of the qualification criteria for the
pathologist. The presence of proteinuria and 50% or more inflammation in tissues with
sufficient cortex increased the number of biopsy samples.
Conclusion: Determination of tissue adequacy during kidney biopsy is an important and
necessary method. The amount of cortex is one of the important parameters in tissue
adequacy.
Primary Language | English |
---|---|
Subjects | Health and Community Services |
Journal Section | Surgical Science Research Articles |
Authors | |
Early Pub Date | June 30, 2023 |
Publication Date | June 30, 2023 |
Acceptance Date | June 23, 2023 |
Published in Issue | Year 2023Volume: 45 Issue: 2 |