Dünya Sağlık Örgütü'nün merkezi sinir sistemi tümörleri sınıflandırmasının 5. baskısı moleküler değişiklikleri histopatoloji ile birleştirerek doğru ve kesin tanılar için genetik testlerin kritik rolünü vurgulamaktadır. Bu durum özellikle ekonomik olarak dezavatajlı ülkelerde zorluklara yol açmaktadır. ADAPTR grubu bu ülkeler için temel histolojik ve immünohistokimyasal belirteçlerle tanının konulabileceğini önermektedir.
Sarkar C, Rao S ,Santosh V, Al_Hussaini M ,Hye Park S ,Tihan T ,Buckland ME, Ng HK , Komori T. Resource availability for CNS tumor diagnostics in the Asian-Oceanian region: A survey by the Asian-Oceanian Society of Neuropathology committee for Adapting Diagnostic Approaches for Practical Taxonomy in Resource-Restrained Regions (AOSNP-ADAPTR). Brain Pathology 2025. https://doi.org/10.1111/bpa.13329.
World Health Organization classification of central nervous system tumors
The fifth edition of the World Health Organization classification of central nervous system tumors (WHO CNS5) now integrates molecular alterations along with histopathology, emphasizing the crucial role of genetic testing for precise and accurate diagnoses.This development poses significant challenges, particularly in economically disadvantaged countries. ADAPTR group will focus on utilizing histopathology supplemented by basic and surrogate IHC markers
Sarkar C, Rao S ,Santosh V, Al_Hussaini M ,Hye Park S ,Tihan T ,Buckland ME, Ng HK , Komori T. Resource availability for CNS tumor diagnostics in the Asian-Oceanian region: A survey by the Asian-Oceanian Society of Neuropathology committee for Adapting Diagnostic Approaches for Practical Taxonomy in Resource-Restrained Regions (AOSNP-ADAPTR). Brain Pathology 2025. https://doi.org/10.1111/bpa.13329.