Research Article
Year 2018,
Volume: 3 Issue: 2, 16 - 20, 31.08.2018
Abstract
Amaç: Bu saha çalışması giardiasisli kuzularda oral yolla uygulanan klinoptilolitin etkinliğinin
belirlenmesi amacıyla gerçekleştirildi.
Yöntemler: Aydın ili sınırlarında yer alan özel bir işletmede ishal mevcut ve G. duodenalis ile
doğal enfekte her iki cinsiyetten ve 23-56 günlük yaştaki 14 kuzu değerlendirildi. Tanı amacıyla
ELISA prensibi ile çalışan hızlı tanısal test kitleri yapıldı. Giardiazisli kuzular her grupta n=7
olarak rastgele I. gruba [1 g/kg dozda 10 gün oral yolla klinoptilolit uygulanırken] ya da II. gruba
[ilaç uygulaması yapılmaksızın kontrol grubu] ayırıldı. Klinoptilolitin sağaltım etkinliği 0. ve 10.
günlerde rektal yolla elde edilen dışkı örneklerinin mikroskobik muayenesiyle değerlendirildi.
Bulgular: Kontrol ve sağaltım grupları arasında karşılaştırmalarda 10. günde klinoptilolit ile
sağaltılan grupta kist atılımında % 97,2’lik azalma belirgindi (p 0˂0,05).
Sonuç: Giardiazisli kuzularda oral yolla 10 gün uygulanan klinoptilolitin kist atılımını etkin
şekilde azalttığı ve antiparaziter etkinlik sağladığı görüldü.
Keywords
References
- Alıç Ural, D., Aysul, N., Gultekin, M. (2016). The Efficacy of Oral Administration of Clinoptilolite Against Naturally Occuring Giardiasis in Calves. Kocatepe Vet J, 9(4), 288-293. DOI: 10.5578/kvj.28122Alıç Ural, D., Erdoğan, H., Toplu, S., Ayan, A. (2017). Oğlaklarda Giardiazis Kontrolüne Yönelik Oral Klinoptilolit Uygulaması. Kocatepe Vet J, 10(3), 158-163. DOI:10.5578/kvj.57512Aloisio, F., Filippini, G., Antenucci, P., Lepri, E., Pezzotti, G., Cacciò, SM. (2006). Severe weight loss in lambs infected with Giardia duodenalis assemblage B. Vet Parasitol, 142(1-2), 154-158. DOI:10.1016/j.vetpar.2006.06.023Ayan, A., Ural, K., Aysul, N., Gültekin, M., Erdoğan, H., Balıkçı, C., Toplu, S., Toros, G. (2016). Natural Cyst Shedding in Calves Infected with Giardia duodenalis. JAVST, 1(1), 14-19.Caccio, S.M. (2015). Giardiasis: a zoonotic infection or not? In: Sing A (ed’s), Zoonoses-ınfections affecting humans and animals. New-York (NY), Springer, 821-848.Cacció, S.M., de Giacomo, M., Pozio, E. (2002). Sequence analysis of the β giardin gene and development of a PCR-RFLP assay to genotype Giardia duodenalis cysts from human faecal samples. Int J Parasitol, 32(8), 1023-1030. DOI:10.1016/S0020-7519(02)00068-1Ey, PL., Mansouri, M., Kulda, J., Nohynkova, E., Monis, P.T., Andrews, R.H., Mayrhofer, G. (1997). Genetic analysis of Giardia from hoofed farm animals reveals artiodactyls-specific and potentially zoonotic genotypes. J Eukaryot Microbiol, 44(6), 625-635. Geurden, T., Thomas, P., Casaert, S., Vercruysse, J., Claerebout, E. (2008). Prevalence and molecular characterization of Cryptosporidium and Giardia in lambs and goat kids in Belgium. Vet Parasitol, 155(1-2), 142-145. DOI:10.1016/j.vetpar.2008.05.002Geurden, T., Vercruysse, J., Claerebout, E. (2010). Is Giardia a signifcant pathogen in production animals? Exp Parasitol, 124(1), 98-106. DOI:10.1016/j.exppara.2009.03.001
- Geurden, T., Pohleb, H., Sarrea, C., Dreesena, L., Vercruyssea, J., Claerebouta, E. (2011). The effcacy of a treatment with fenbendazole against an experimental Giardia duodenalis infection in lambs. Small Rum Res, 96(2-3), 211-215. DOI:10.1016/j.smallrumres.2010.12.004Giangaspero, A., Paoletti, B., Iorio, R., Traversa, D. (2005). Prevalence and molecular characterization of Giardia duodenalis from sheep in central Italy. J Parasitol Res, 96(1), 32-37. DOI:10.1007/s00436-005-1317-7Gultekin, M., Ural, K., Aysul, N., Ayan, A., Balikci, C., Akyildiz, G. (2016). The efficacy of chloroquine treatment of Giardia duodenalis infection in calves. Vlaams Diergeneeskd Tijdschr, 85(6): 335-41.Gultekin, M., Ural, K., Aysul, N., Ayan, A., Balikci, C., Akyildiz, G. (2017). Prevalence and molecular characterization of Giardia duodenalis in dogs in Aydin, Turkey. Int J Environ Health Res, 27(3), 161-168. DOI:10.1080/09603123.2017.1310187Gultekin, M., Ural, K., Aysul, N., Ayan, A., Balikci, C., Toplu, S., Akyildiz, G. (2017). Prevalence and molecular characterization of Giardia duodenalis in calves in Turkey. Acta Sci Vet, 45(1450), 1-6. DOI:10.22456/1679-9216.80032Henderson, D.F., Tilton, E.W. (1955). Tests with acaricides against the brown wheat mite. J Econ Entomol, 48(2), 157-161. DOI:10.1093/jee/48.2.157Karahalli C, Ural K. (2017). Single dose secnidazol treatment efficacy against naturally occurring Giardia duodenalis infection in dogs. Magy Allatorvosok Lapja, 139(10), 621-30.Karanis, P., Ey, P.L. (1998). Characterization of axenic isolates of Giardia intestinalis established from humans and animals in Germany. J Parasitol Res, 84, 442-449.Lalle, M., Pozio, E., Capelli, G., Bruschi, F., Crotti, D., Cacció, S.M. (2005). Genetic heterogeneity at the ß-giardin locus among human and animal isolates of Giardia duodenalis and identification of potentially zoonotic subgenotypes. Int J Parasitol, 35(2), 207-213. DOI: 10.1016/j.ijpara.2004.10.022Lebbad, M., Mattsson, J.G., Christensson, B., Ljungström, B., Backhans, A., Andersson, J.O., Svärd, S.G. (2010). From mouse to moose: multilocus genotyping of Giardia isolates from various animal species. Vet Parasitol, 168(3-4), 231-239. DOI:10.1016/j.vetpar.2009.11.003O’Handley, R.M., Cockwill, C., Jelinski, M., McAllister, T.A., Olson, M.E. (2000). Effects of repeat fenbendazole treatment in dairy calves with giardiosis on cyst excretion, clinical signs and production. Vet Parasitol, 89(3), 209-218. DOI:10.1016/S0304-4017(00)00200-4Olson, M.E., O’Handley, R.M., Ralston, B.J., McAllister, TA., Thompson, R.C. (2004). Update on Cryptosporidium and Giardia infections in cattle. Trends Parasitol, 20(4), 185-191. DOI:10.1016/j.pt.2004.01.015Prado, M.S., Cairncross, S., Strina, A., Barreto, M.L., Oliveira-Assis, A.M., Rego, S. (2005). Asymptomatic giardiasis and growth in young children; a longitudinal study in Salvador, Brazil. Parasitology, 131(1), 51-56. DOI:10.1017/S0031182005007353Ragbetli, C., Tanritanir, P., Yilmaz, H., Yoruk, I., Ozdemir, H. (2014). Effect on biochemical parameters in naturally infected calves with giardiasis after treatment with albendazole in Van Province, Turkey. Indian J Anim Sci, 48(1), 38-44. DOI:10.5958/j.0976-0555.48.1.008Robertson, L.J. (2009). Giardia and Cryptosporidium infections in sheep and goats: A review of the potential for transmission to humans via environmental contamination. Epidemiol Infect, 137(7), 913-921. DOI: 10.1017/S0950268809002295.Thompson, R.C., Palmer, C.S., O’Handley, R. (2008). The public health and clinical significance of Giardia and Cryptosporidium in domestic animals. Vet J, 177(1), 18-25. DOI:10.1016/j.tvjl.2007.09.022Toplu, S., Ural, K., Aysul, N., Ayan, A., Gültekin, M., Balıkçı, C. (2016). Hypomagnesaemia In Naturally Infected Calves with Giardia Spp. Kocatepe Vet J, 9(4), 386-390. DOI: 10.5578/kvj.37335Ural, K., Aysul, N., Voyvoda, H., Ulutas, B., Aldemir, O.S., Eren, H. (2014). Single dose of secnidazole treatment against naturally occuring Giardia duodenalis infection in Sakiz lambs. Rev MVZ Cordoba, 19(1), 4023-4032. DOI:10.21897/rmvz.122Ural, K., Gultekin, M., Pasa, S., Aysul, N., Ayan, A. (2017). Chloroquine treatment against naturally occuring Giardia duodenalis infection in dogs. Med Weter, 73(5), 280-283. DOI: 10.21521/mw.5695
Year 2018,
Volume: 3 Issue: 2, 16 - 20, 31.08.2018
Abstract
Objective The aim of this field study was to detect the therapeutic efficacy of oral clinoptilolite
in lambs with giardiasis.
Methods: A total of fourteen lambs naturally infected with G. duodenalis at the age of 23 to 56
days, of both sexes were enrolled into the study from a lamb farm located in Aydin province.
Diagnosis was based on rapid diagnositc test kits with ELISA principle. Lambs with giardiasis
were randomly assigned into two groups (n=7), group I [1 g/kg clinoptilolite for 10 days or group
II [were left as control without receiving any drug]. Therapeutic efficacy of clinoptilolite was
determined by microscopical examination of faecal samples collected rectally on days 0 and 10.
Results: Comparison of control and treatment intragroups revealed 97,2% reduction (p 0˂0,05)
for cyst excretion in clinoptilolite treated group.
Conclusion: In conclusion, it may be safey suggested that oral clinoptilolite administration for
10 days effectively reduct cyst excretion with antiparasitic efficacy among lambs with giardiasis.
Keywords
References
- Alıç Ural, D., Aysul, N., Gultekin, M. (2016). The Efficacy of Oral Administration of Clinoptilolite Against Naturally Occuring Giardiasis in Calves. Kocatepe Vet J, 9(4), 288-293. DOI: 10.5578/kvj.28122Alıç Ural, D., Erdoğan, H., Toplu, S., Ayan, A. (2017). Oğlaklarda Giardiazis Kontrolüne Yönelik Oral Klinoptilolit Uygulaması. Kocatepe Vet J, 10(3), 158-163. DOI:10.5578/kvj.57512Aloisio, F., Filippini, G., Antenucci, P., Lepri, E., Pezzotti, G., Cacciò, SM. (2006). Severe weight loss in lambs infected with Giardia duodenalis assemblage B. Vet Parasitol, 142(1-2), 154-158. DOI:10.1016/j.vetpar.2006.06.023Ayan, A., Ural, K., Aysul, N., Gültekin, M., Erdoğan, H., Balıkçı, C., Toplu, S., Toros, G. (2016). Natural Cyst Shedding in Calves Infected with Giardia duodenalis. JAVST, 1(1), 14-19.Caccio, S.M. (2015). Giardiasis: a zoonotic infection or not? In: Sing A (ed’s), Zoonoses-ınfections affecting humans and animals. New-York (NY), Springer, 821-848.Cacció, S.M., de Giacomo, M., Pozio, E. (2002). Sequence analysis of the β giardin gene and development of a PCR-RFLP assay to genotype Giardia duodenalis cysts from human faecal samples. Int J Parasitol, 32(8), 1023-1030. DOI:10.1016/S0020-7519(02)00068-1Ey, PL., Mansouri, M., Kulda, J., Nohynkova, E., Monis, P.T., Andrews, R.H., Mayrhofer, G. (1997). Genetic analysis of Giardia from hoofed farm animals reveals artiodactyls-specific and potentially zoonotic genotypes. J Eukaryot Microbiol, 44(6), 625-635. Geurden, T., Thomas, P., Casaert, S., Vercruysse, J., Claerebout, E. (2008). Prevalence and molecular characterization of Cryptosporidium and Giardia in lambs and goat kids in Belgium. Vet Parasitol, 155(1-2), 142-145. DOI:10.1016/j.vetpar.2008.05.002Geurden, T., Vercruysse, J., Claerebout, E. (2010). Is Giardia a signifcant pathogen in production animals? Exp Parasitol, 124(1), 98-106. DOI:10.1016/j.exppara.2009.03.001
- Geurden, T., Pohleb, H., Sarrea, C., Dreesena, L., Vercruyssea, J., Claerebouta, E. (2011). The effcacy of a treatment with fenbendazole against an experimental Giardia duodenalis infection in lambs. Small Rum Res, 96(2-3), 211-215. DOI:10.1016/j.smallrumres.2010.12.004Giangaspero, A., Paoletti, B., Iorio, R., Traversa, D. (2005). Prevalence and molecular characterization of Giardia duodenalis from sheep in central Italy. J Parasitol Res, 96(1), 32-37. DOI:10.1007/s00436-005-1317-7Gultekin, M., Ural, K., Aysul, N., Ayan, A., Balikci, C., Akyildiz, G. (2016). The efficacy of chloroquine treatment of Giardia duodenalis infection in calves. Vlaams Diergeneeskd Tijdschr, 85(6): 335-41.Gultekin, M., Ural, K., Aysul, N., Ayan, A., Balikci, C., Akyildiz, G. (2017). Prevalence and molecular characterization of Giardia duodenalis in dogs in Aydin, Turkey. Int J Environ Health Res, 27(3), 161-168. DOI:10.1080/09603123.2017.1310187Gultekin, M., Ural, K., Aysul, N., Ayan, A., Balikci, C., Toplu, S., Akyildiz, G. (2017). Prevalence and molecular characterization of Giardia duodenalis in calves in Turkey. Acta Sci Vet, 45(1450), 1-6. DOI:10.22456/1679-9216.80032Henderson, D.F., Tilton, E.W. (1955). Tests with acaricides against the brown wheat mite. J Econ Entomol, 48(2), 157-161. DOI:10.1093/jee/48.2.157Karahalli C, Ural K. (2017). Single dose secnidazol treatment efficacy against naturally occurring Giardia duodenalis infection in dogs. Magy Allatorvosok Lapja, 139(10), 621-30.Karanis, P., Ey, P.L. (1998). Characterization of axenic isolates of Giardia intestinalis established from humans and animals in Germany. J Parasitol Res, 84, 442-449.Lalle, M., Pozio, E., Capelli, G., Bruschi, F., Crotti, D., Cacció, S.M. (2005). Genetic heterogeneity at the ß-giardin locus among human and animal isolates of Giardia duodenalis and identification of potentially zoonotic subgenotypes. Int J Parasitol, 35(2), 207-213. DOI: 10.1016/j.ijpara.2004.10.022Lebbad, M., Mattsson, J.G., Christensson, B., Ljungström, B., Backhans, A., Andersson, J.O., Svärd, S.G. (2010). From mouse to moose: multilocus genotyping of Giardia isolates from various animal species. Vet Parasitol, 168(3-4), 231-239. DOI:10.1016/j.vetpar.2009.11.003O’Handley, R.M., Cockwill, C., Jelinski, M., McAllister, T.A., Olson, M.E. (2000). Effects of repeat fenbendazole treatment in dairy calves with giardiosis on cyst excretion, clinical signs and production. Vet Parasitol, 89(3), 209-218. DOI:10.1016/S0304-4017(00)00200-4Olson, M.E., O’Handley, R.M., Ralston, B.J., McAllister, TA., Thompson, R.C. (2004). Update on Cryptosporidium and Giardia infections in cattle. Trends Parasitol, 20(4), 185-191. DOI:10.1016/j.pt.2004.01.015Prado, M.S., Cairncross, S., Strina, A., Barreto, M.L., Oliveira-Assis, A.M., Rego, S. (2005). Asymptomatic giardiasis and growth in young children; a longitudinal study in Salvador, Brazil. Parasitology, 131(1), 51-56. DOI:10.1017/S0031182005007353Ragbetli, C., Tanritanir, P., Yilmaz, H., Yoruk, I., Ozdemir, H. (2014). Effect on biochemical parameters in naturally infected calves with giardiasis after treatment with albendazole in Van Province, Turkey. Indian J Anim Sci, 48(1), 38-44. DOI:10.5958/j.0976-0555.48.1.008Robertson, L.J. (2009). Giardia and Cryptosporidium infections in sheep and goats: A review of the potential for transmission to humans via environmental contamination. Epidemiol Infect, 137(7), 913-921. DOI: 10.1017/S0950268809002295.Thompson, R.C., Palmer, C.S., O’Handley, R. (2008). The public health and clinical significance of Giardia and Cryptosporidium in domestic animals. Vet J, 177(1), 18-25. DOI:10.1016/j.tvjl.2007.09.022Toplu, S., Ural, K., Aysul, N., Ayan, A., Gültekin, M., Balıkçı, C. (2016). Hypomagnesaemia In Naturally Infected Calves with Giardia Spp. Kocatepe Vet J, 9(4), 386-390. DOI: 10.5578/kvj.37335Ural, K., Aysul, N., Voyvoda, H., Ulutas, B., Aldemir, O.S., Eren, H. (2014). Single dose of secnidazole treatment against naturally occuring Giardia duodenalis infection in Sakiz lambs. Rev MVZ Cordoba, 19(1), 4023-4032. DOI:10.21897/rmvz.122Ural, K., Gultekin, M., Pasa, S., Aysul, N., Ayan, A. (2017). Chloroquine treatment against naturally occuring Giardia duodenalis infection in dogs. Med Weter, 73(5), 280-283. DOI: 10.21521/mw.5695
There are 2 citations in total.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Veterinary Surgery |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | August 31, 2018 |
| Submission Date | March 30, 2018 |
| Acceptance Date | August 29, 2018 |
| Published in Issue | Year 2018 Volume: 3 Issue: 2 |
