Diagnostic Contribution of Diffusion-Weighted Imaging in Liver Hemangiomas

Recep İsmail Akın; Mehmet Atalar; Nisa Bozbıyık; Büşra Şeker; Gökhan Yılmaz

doi:10.7197/cmj.1324648

EN TR

Diagnostic Contribution of Diffusion-Weighted Imaging in Liver Hemangiomas

Abstract

Objective: The purpose of this study is to evaluate the contribution of diffusion weighted (DWI) MRI and measured appearent diffusion coefficient (ADC) values in hepatic hemanjiomas. Methods: The study population consisted of 70 patients with liver hemangiomas. DWI examination with a b value of 800 s/mm2 was carried out for all patients. After DWI examination, an ADC map was created and ADC values were measured for 70 liver masses and normal liver tissue (control group). ADC measurement of 70 normal liver parenchyma and, mean ADC values of 80 hemangiomas are performed. Results: Eighty hemangiomas of 70 patients composed by 50 women and 20 men are evaluated in our study. Age of the patients who included to study are between 26 and 73 and the mean age was calculated 49.61 ± 10.96. Hemangiomas are shown most highly at segment 7 (%28.8) and segment 6 (%21.3), and least at segment 5 (%5). While the mean ADC measurement of normal livers of patientes are included to study was 1.06 ± 0.11 x 10-3 mm2 /s, the mean ADC value of hemangiomas was measured 1.70 ± 0.29 x 10-3 mm2/s. Conclusion: DWI, and measurements of ADC values obtained from process are useful for the diagnosis of hemangioma. We think that DWI should be routinely added to convantional MR sequences.

Keywords

Karaciğer Hemanjiyomlarında Difüzyon Ağırlıklı Görüntülemenin Tanısal Katkısı

Öz

Amaç: Bu çalışmanın amacı, hepatik hemanjiomlarda difüzyon ağırlıklı (DAG) MR ve ölçülen görünen difüzyon katsayısı (GDK) değerlerinin katkısını değerlendirmektir. Yöntem: Çalışma grubunu karaciğer hemanjiomlu 70 hasta oluşturdu. Tüm hastalara b değeri 800 s/mm2 olan DAG incelemesi yapıldı. DAG incelemesi sonrasında GDK haritası oluşturuldu ve 70 karaciğer kitlesi ve normal karaciğer dokusu (kontrol grubu) için GDK değerleri ölçüldü. 70 normal karaciğer parankiminin GDK ölçümü ve 80 hemanjiomun ortalama GDK değerleri yapıldı. Bulgular: Çalışmamızda 50'si kadın, 20'si erkek olmak üzere 70 hastanın 80 hemanjiyomu değerlendirildi. Çalışmaya alınan hastaların yaşları 26 ile 73 arasında olup yaş ortalaması 49,61±10,96 olarak hesaplandı. Hemanjiomlar en fazla segment 7 (%28,8) ve segment 6'da (%21,3), en az ise segment 5'te (%5) görülmektedir. Çalışmaya dahil edilen hastaların normal karaciğerlerinin ortalama GDK ölçümü 1,06 ± 0,11 x 10-3 mm2/sn iken, hemanjiomların ortalama GDK değeri 1,70 ± 0,29 x 10-3 mm2/sn olarak ölçüldü. Sonuç: DAG ve işlem sonrası elde edilen GDK değerlerinin ölçümü hemanjiyom tanısı için faydalıdır. Geleneksel MR sekanslarına DAG'nin rutin olarak eklenmesi gerektiğini düşünüyoruz.

Anahtar Kelimeler

Kaynakça

Vilgrain V, Boulos L, Vullierme MP et al. Y. Imaging of atypical hemangiomas of the liver with pathologic correlation. Radiographics 2000; 20: 379-7.
Motohara T, Semelka RC, Nagase L. MR imaging of benign hepatic tumors. Magn Reson Imaging Clin N Am 2002; 10: 1-14.
Whitney WS, Herfkens RJ, Jeffrey RB et al. Dynamic breath-hold multiplanar spoiled gradient-recalled MR imaging with gadolinium enhancement for differentiating hepatic hemangiomas from malignancies at 1.5 T. Radiology 1993; 189: 863-70.
Taouli B, Koh DM. Diffusion-weighted MR imaging of the liver. Radiology 2009; 254: 47-66.
Le D Bihan. Molecular diffusion nuclear magnetic resonance imaging. Magn Reson Q 1991; 7: 1-30.
Müller MF, Edelman RR. Echo planar imaging of the abdomen. Top Magn Reson Imaging. 1995; 7: 112-9.
Koike N, Cho A, Nasu K et al. Role of diffusion-weighted magnetic resonance imaging in the differential diagnosis of focal hepatic lesions. World J Gastroenterol 2009; 15: 5805-12.
Moteki T, Horikoshi H. Evaluation of hepatic lesions and hepatic parenchyma using diffusion‐weighted echo‐planar MR with three values of gradient b‐factor. J Magn Reson Imaging 2006; 24: 637-45.

Onur MR, Çiçekçi M, Kayalı A et al. The role of ADC measurement in differential diagnosis of focal hepatic lesions. Eur J Radiol 2012; 81: e171-6.
Testa ML, Chojniak R, Sene LS et al. Is DWI/ADC a useful tool in the characterization of focal hepatic lesions suspected of malignancy? PloS one 2014; 9: e101944.
Elsayes KM, Narra VR, Yin Y et al. Focal hepatic lesions: diagnostic value of enhancement pattern approach with contrast-enhanced 3D gradient-echo MR imaging. Radiographics 2005; 25: 1299-1320.
Jahic E, Sofic A, Selimovic AH. DWI/ADC in differentiation of benign from malignant focal liver lesion. Acta Inform Med 2016; 24: 244-7.
Nasu K, Kuroki Y, Nawano S et al. Hepatic metastases: diffusion-weighted sensitivity-encoding versus SPIO-enhanced MR imaging. Radiology 2006; 239: 122-30.
Ichikawa T, Haradome H, Hachiya J et al. Diffusion-weighted MR imaging with a single-shot echoplanar sequence: detection and characterization of focal hepatic lesions. AJR Am J Roentgenol 1998;170: 397-402.
Demir Öİ, Obuz F, Sagol O, Dicle O. Contribution of diffusion-weighted MRI to the differential diagnosis of hepatic masses. Diagn Interv Radiol 2007; 13: 81-6
Sandrasegaran K, Akisik FM, Lin C et al. The value of diffusion-weighted imaging in characterizing focal liver masses. Acad Radiol 2009; 16: 1208-14.
Tokgoz O, Unlu E, Unal I et al. Diagnostic value of diffusion weighted MRI and ADC in differential diagnosis of cavernous hemangioma of the liver. Afr Health Sci 2016; 16: 227-33.
Schmid-Tannwald C, Jiang Y, Dahi F et al. Diffusion-weighted MR imaging of focal liver lesions in the left and right lobes: is there a difference in ADC values? Acad Radiol 2013; 20: 440-5.
Soyer P, Corno L, Boudiaf Met al. Differentiation between cavernous hemangiomas and untreated malignant neoplasms of the liver with free-breathing diffusion-weighted MR imaging: comparison with T2-weighted fast spin-echo MR imaging. Eur J Radiol 2011; 80: 316-24.
Ichikawa T, Haradome H, Hachiya J et al. Diffusion-weighted MR imaging with single-shot echo-planar imaging in the upper abdomen: preliminary clinical experience in 61 patients. Abdom Imaging 1999; 24: 456-61.
Gourtsoyianni S, Papanikolaou N, Yarmenitis S et al. Respiratory gated diffusion-weighted imaging of the liver: value of apparent diffusion coefficient measurements in the differentiation between most commonly encountered benign and malignant focal liver lesions. Eur Radiol 2008; 18: 486-92.
Naganawa S, Kawai H, Fukatsu H, et al. Diffusion-weighted imaging of the liver: technical challenges and prospects for the future. Magn Reson Med Sci 2005; 4: 175-86.
Taouli B, Vilgrain V, Dumont E et al. Evaluation of liver diffusion isotropy and characterization of focal hepatic lesions with two single-shot echo-planar MR imaging sequences: prospective study in 66 patients. Radiology 2003; 226: 71-8.
Namimoto T, Yamashita Y, Sumi S et al. Focal liver masses: characterization with diffusion-weighted echo-planar MR imaging. Radiology 1997; 204: 739-44.
Bozgeyik Z, Kocakoc E, Gul Y, Dagli AF. Evaluation of liver hemangiomas using three different b values on diffusion MR. Eur J Radiol 2010; 75: 360-3.
Parikh T, Drew SJ, Lee VS et al. Focal liver lesion detection and characterization with diffusion-weighted MR imaging: comparison with standard breath-hold T2-weighted imaging. Radiology 2008; 246: 812-22.
Bruegel M, Rummeny EJ. Hepatic metastases: use of diffusion-weighted echo-planar imaging. Abdom Imaging 2010; 35: 454-61.
Bruegel M, Holzapfel K, Gaa J et al. Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion-weighted single-shot echo-planar MR imaging technique. Eur Radiol 2008; 18: 477-85.
Goshima S, Kanematsu M, Kondo H et al. Hepatic hemangioma: correlation of enhancement types with diffusion-weighted MR findings and apparent diffusion coefficients. Eur J Radiol 2009; 70: 325-30.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Sistemleri

Bölüm

Araştırma Makalesi

Yazarlar

Recep İsmail Akın
0000-0003-4390-8150
Türkiye

Mehmet Atalar ^*
0000-0003-3076-8072
Türkiye

Nisa Bozbıyık
0000-0003-4240-6001
Türkiye

Büşra Şeker
0000-0001-7766-4276
Türkiye

Gökhan Yılmaz
0000-0003-4073-0668
Türkiye

Yayımlanma Tarihi

29 Mart 2024

Gönderilme Tarihi

17 Temmuz 2023

Kabul Tarihi

7 Mart 2024

Yayımlandığı Sayı

Yıl 2024 Cilt: 46 Sayı: 1

DOI

https://doi.org/10.7197/cmj.1324648

IZ

https://izlik.org/JA43WU67YN

Kaynak Göster

RIS / Bibtex

AMA

1.Akın Rİ, Atalar M, Bozbıyık N, Şeker B, Yılmaz G. Diagnostic Contribution of Diffusion-Weighted Imaging in Liver Hemangiomas. CMJ. 2024;46(1):52-56. doi:10.7197/cmj.1324648