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The Demographic and Clinical Profile of Patients Presenting with Pruritus to the Dermatology Clinic of Bayburt Province: A Single-Center Study

Yıl 2025, Cilt: 47 Sayı: 4, 26 - 31, 31.12.2025

Sena Kocabiyik

Öz

Background:
Pruritus (itching) is a common symptom observed in dermatology outpatient clinics that has a significant negative impact on patients’ quality of life. Its etiology is broad, encompassing dermatological, systemic, neurogenic, and psychogenic causes. This study aimed to evaluate the demographic, clinical, and therapeutic characteristics of patients with pruritus.
Methods:
This retrospective descriptive study included patients aged> 18 years who presented with pruritus at the Dermatology Clinic of Bayburt State Hospital between September 19, 2024, and October 9, 2025. Initially, 200 cases were evaluated; however, 120 were excluded owing to incomplete clinical data or temporary causes, leaving 80 patients included in the final analysis. Data were obtained from the hospital information management system, and variables such as age, sex, occupation, diagnostic category, and type of treatment were analyzed.
Results:
The mean age of the patients was 50.2 ± 16.4 years; 51.3% were female and 48.8% were male. The most common occupational groups were homemakers (31.3%) and retirees (25.0%). Among the causes of pruritus, eczematous/inflammatory dermatoses ranked first (35 cases, 43.8%), followed by infectious/parasitic dermatoses (31 cases, 38.8%). Reactive/neurogenic and papulosquamous dermatoses were observed in 8.8% of cases. The most frequently preferred treatment was a combination of topical corticosteroids and emollients (51.3%) (p < 0.001).
Conclusion:
The most common cause of pruritus was dermatological disease, particularly eczematous and infectious dermatoses. Reactive/neurogenic itching was observed more frequently in women than in men. These findings highlight the multifactorial nature of pruritus and emphasize the importance of individualized etiology-based treatment.

Anahtar Kelimeler

Pruritus etiology treatment dermatology

Kaynakça

  • 1. Bernhard JD. Itch and pruritus: what are they, and how should itches be classified? Dermatol Ther. 2005;18(4):288-291.
  • 2. Butler DC, Berger T, Elmariah S, et al. Chronic pruritus: a review. JAMA. 2024;331(24):2114-2124.
  • 3. Aboeldahab S, Khalil F, Ezz Eldawla R. Clinical and laboratory characteristics of elderly patients with pruritus. Clin Cosmet Investig Dermatol. 2021;14:1009-1015.
  • 4. Steinhoff M, Al-Khawaga S, Buddenkotte J. Itch in elderly patients: origin, diagnostics, management. J Allergy Clin Immunol. 2023;152(1):42-49.
  • 5. Takanami K, Uta D, Matsuda KI, et al. Estrogens influence female itch sensitivity via the spinal gastrin-releasing peptide receptor neurons. Proc Natl Acad Sci U S A. 2021;118(31):e2103536118.
  • 6. Stefaniak AA, Pereira MP, Zeidler C, Ständer S. Pruritus in pregnancy. Am J Clin Dermatol. 2022;23(2):231-246.
  • 7. McMaster HG, Holden RM, Scott M, Iliescu E. Prevalence and severity of pruritus in patients on hemodialysis: a cross-sectional study. Can J Kidney Health Dis. 2025;12:20543581251380541.
  • 8. Agarwal P, Garg V, Karagaiah P, et al. Chronic kidney disease-associated pruritus. Toxins. 2021;13(8):527.
  • 9. Hashimoto T, Okuno S. Practical guide for the diagnosis and treatment of localized and generalized cutaneous pruritus. J Dermatol. 2025;52(2):204-220.
  • 10. Kalra S, Mittal A, Rathod RM, et al. Knowledge, attitude and practice for pruritus management in physicians and patients with diabetes. Clin Pract. 2022;12(1):27-36.
  • 11. Rowe B, Yosipovitch G. Malignancy-associated pruritus. Eur J Pain. 2016;20(1):19-23.
  • 12. Krajnik M, Zylicz Z. Understanding pruritus in systemic disease. J Pain Symptom Manage. 2001;21(2):151-168.
  • 13. Weisshaar E, Kucenic MJ, Fleischer AB Jr. Pruritus: a review. Acta Derm Venereol. 2003;83:5-32.
  • 14. Kwatra SG, Kambala A, Dong X. Neuropathic pruritus. J Allergy Clin Immunol. 2023;152(1):36-38.
  • 15. Ständer S, Weisshaar E, Mettang T, et al. Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Derm Venereol. 2007;87(4):291-294.
  • 16. Reich A, Ständer S, Szepietowski JC. Pruritus in the elderly. Clin Dermatol. 2011;29(1):15-23.
  • 17. Valdes-Rodriguez R, Stull C, Yosipovitch G. Chronic pruritus in the elderly: pathophysiology, diagnosis and management. Drugs Aging. 2015;32(3):201-215.
  • 18. Matterne U, Apfelbacher CJ, Loerbroks A, et al. Prevalence, correlates and characteristics of chronic pruritus: a population-based cross-sectional study. Acta Derm Venereol. 2011;91(6):674-679.
  • 19. Ständer S, Stumpf A, Osada N, et al. Gender differences in chronic pruritus: women present different morbidity, more scratch lesions and higher burden. Br J Dermatol. 2013;168(6):1273-1280.
  • 20. Proksch E, Brandner JM, Jensen JM. The skin: an indispensable barrier. Exp Dermatol. 2008;17(12):1063-1072.
  • 21. Elias PM, Steinhoff M. “Outside-to-inside” (and now back to “outside”) pathogenic mechanisms in atopic dermatitis. J Invest Dermatol. 2008;128(5):1067-1070.
  • 22. Weisshaar E, Szepietowski JC, Dalgard FJ, et al. European S2k guideline on chronic pruritus. Acta Derm Venereol. 2019;99(5):469-506.
  • 23. Fernando DD, Mounsey KE, Bernigaud C, et al. Scabies. Nat Rev Dis Primers. 2024;10(1):74.
  • 24. Bağci IS, Ruzicka T. IL-31: a new key player in dermatology and beyond. J Allergy Clin Immunol. 2018;141(3):858-866.
  • 25. Ständer S, Schmelz M. Chronic itch and pain—similarities and differences. Eur J Pain. 2006;10(5):473-478.

Bayburt İli Dermatoloji Kliniğine Pruritus ile Başvuran Hastaların Demografik ve Klinik Profili: Tek Merkezli Bir Çalışma

Yıl 2025, Cilt: 47 Sayı: 4, 26 - 31, 31.12.2025

Sena Kocabiyik

Öz

Arka Plan:
Pruritus (kaşıntı), dermatolojik poliklinik başvurularında sık görülen, yaşam kalitesini olumsuz etkileyen bir semptomdur. Etiyolojisi oldukça geniş olup dermatolojik, sistemik, nörojenik ve psikojenik nedenlerle ortaya çıkabilir. Bu çalışmada, pruritus yakınmasıyla başvuran hastaların demografik, klinik ve tedavi özelliklerinin değerlendirilmesi amaçlanmıştır.
Yöntem:
Bu retrospektif tanımlayıcı çalışma, 19 Eylül 2024 – 9 Ekim 2025 tarihleri arasında Bayburt Devlet Hastanesi Dermatoloji Kliniği’ne pruritus şikâyetiyle başvuran 18 yaş üzeri hastaları kapsamaktadır. Başlangıçta 200 olgu değerlendirilmiş, eksik klinik veriler ve geçici nedenlerle 120 olgu dışlanarak 80 hasta çalışmaya dâhil edilmiştir. Veriler hastane bilgi yönetim sistemi üzerinden elde edilmiş; yaş, cinsiyet, meslek, tanı grubu ve tedavi türleri analiz edilmiştir.
Bulgular:
Olguların yaş ortalaması 50,2±16,4 olup, %51,3’ü kadın ve %48,8’i erkekti. En sık meslek grubu ev hanımları (%31,3) ve emekliler (%25,0) idi. Pruritus nedenleri arasında ekzematöz/enflamatuvar dermatozlar 35 olgu (%43,8) ile ilk sırada, enfeksiyöz/paraziter dermatozlar ise 31 olgu (%38,8) ile ikinci sırada yer aldı. Reaktif/nörojenik ve papüloskuamöz dermatozlar her biri %8,8 oranında izlendi. Tedavi olarak en sık topikal kortikosteroid ve emoliyan kombinasyonu (%51,3) tercih edildi (p < 0,001).
Sonuç:
Pruritusun en sık nedeni dermatolojik hastalıklar olup özellikle ekzematöz ve enfeksiyöz dermatozlar ön plandadır. Reaktif/nörojenik kaşıntı kadınlarda daha yaygın izlenmiştir. Bulgular, kaşıntının multifaktöriyel doğasını ve bireyselleştirilmiş, etiyolojiye dayalı tedavi yaklaşımlarının önemini vurgulamaktadır.

Anahtar Kelimeler

Pruritus etyoloji tedavi dermatoloji

Kaynakça

  • 1. Bernhard JD. Itch and pruritus: what are they, and how should itches be classified? Dermatol Ther. 2005;18(4):288-291.
  • 2. Butler DC, Berger T, Elmariah S, et al. Chronic pruritus: a review. JAMA. 2024;331(24):2114-2124.
  • 3. Aboeldahab S, Khalil F, Ezz Eldawla R. Clinical and laboratory characteristics of elderly patients with pruritus. Clin Cosmet Investig Dermatol. 2021;14:1009-1015.
  • 4. Steinhoff M, Al-Khawaga S, Buddenkotte J. Itch in elderly patients: origin, diagnostics, management. J Allergy Clin Immunol. 2023;152(1):42-49.
  • 5. Takanami K, Uta D, Matsuda KI, et al. Estrogens influence female itch sensitivity via the spinal gastrin-releasing peptide receptor neurons. Proc Natl Acad Sci U S A. 2021;118(31):e2103536118.
  • 6. Stefaniak AA, Pereira MP, Zeidler C, Ständer S. Pruritus in pregnancy. Am J Clin Dermatol. 2022;23(2):231-246.
  • 7. McMaster HG, Holden RM, Scott M, Iliescu E. Prevalence and severity of pruritus in patients on hemodialysis: a cross-sectional study. Can J Kidney Health Dis. 2025;12:20543581251380541.
  • 8. Agarwal P, Garg V, Karagaiah P, et al. Chronic kidney disease-associated pruritus. Toxins. 2021;13(8):527.
  • 9. Hashimoto T, Okuno S. Practical guide for the diagnosis and treatment of localized and generalized cutaneous pruritus. J Dermatol. 2025;52(2):204-220.
  • 10. Kalra S, Mittal A, Rathod RM, et al. Knowledge, attitude and practice for pruritus management in physicians and patients with diabetes. Clin Pract. 2022;12(1):27-36.
  • 11. Rowe B, Yosipovitch G. Malignancy-associated pruritus. Eur J Pain. 2016;20(1):19-23.
  • 12. Krajnik M, Zylicz Z. Understanding pruritus in systemic disease. J Pain Symptom Manage. 2001;21(2):151-168.
  • 13. Weisshaar E, Kucenic MJ, Fleischer AB Jr. Pruritus: a review. Acta Derm Venereol. 2003;83:5-32.
  • 14. Kwatra SG, Kambala A, Dong X. Neuropathic pruritus. J Allergy Clin Immunol. 2023;152(1):36-38.
  • 15. Ständer S, Weisshaar E, Mettang T, et al. Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Derm Venereol. 2007;87(4):291-294.
  • 16. Reich A, Ständer S, Szepietowski JC. Pruritus in the elderly. Clin Dermatol. 2011;29(1):15-23.
  • 17. Valdes-Rodriguez R, Stull C, Yosipovitch G. Chronic pruritus in the elderly: pathophysiology, diagnosis and management. Drugs Aging. 2015;32(3):201-215.
  • 18. Matterne U, Apfelbacher CJ, Loerbroks A, et al. Prevalence, correlates and characteristics of chronic pruritus: a population-based cross-sectional study. Acta Derm Venereol. 2011;91(6):674-679.
  • 19. Ständer S, Stumpf A, Osada N, et al. Gender differences in chronic pruritus: women present different morbidity, more scratch lesions and higher burden. Br J Dermatol. 2013;168(6):1273-1280.
  • 20. Proksch E, Brandner JM, Jensen JM. The skin: an indispensable barrier. Exp Dermatol. 2008;17(12):1063-1072.
  • 21. Elias PM, Steinhoff M. “Outside-to-inside” (and now back to “outside”) pathogenic mechanisms in atopic dermatitis. J Invest Dermatol. 2008;128(5):1067-1070.
  • 22. Weisshaar E, Szepietowski JC, Dalgard FJ, et al. European S2k guideline on chronic pruritus. Acta Derm Venereol. 2019;99(5):469-506.
  • 23. Fernando DD, Mounsey KE, Bernigaud C, et al. Scabies. Nat Rev Dis Primers. 2024;10(1):74.
  • 24. Bağci IS, Ruzicka T. IL-31: a new key player in dermatology and beyond. J Allergy Clin Immunol. 2018;141(3):858-866.
  • 25. Ständer S, Schmelz M. Chronic itch and pain—similarities and differences. Eur J Pain. 2006;10(5):473-478.
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Hizmetleri ve Sistemleri (Diğer)
Bölüm Araştırma Makalesi
Yazarlar

Sena Kocabiyik 0009-0003-7499-0000

Gönderilme Tarihi 17 Kasım 2025
Kabul Tarihi 3 Aralık 2025
Yayımlanma Tarihi 31 Aralık 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 47 Sayı: 4

Kaynak Göster

AMA Kocabiyik S. The Demographic and Clinical Profile of Patients Presenting with Pruritus to the Dermatology Clinic of Bayburt Province: A Single-Center Study. CMJ. Aralık 2025;47(4):26-31. doi:10.7197/cmj.1825164