HISTOLOGICAL APPROACHES TO DETERMINATION OF STEM CELLS IN NEURAL TUBE DEFECTS WHICH ARE CREATED EXPERIMENTALLY
Öz
Stem cells are cells that are started to be seen in the early stages of development and they have important roles in development of both neural system and other systems. Anomalies that occur with the neural tubes inability to close are known as neural tube defects. Neural tube defects can be due to malfunction of gene area and many mechanisms since the moment neural tube starts to develop. The incidence of neural tube defect is very high in our country and in the world. Therefore, to understand the neural tube defects in the people, necessary data is usually collected by giving teratogen agent to subject animals. With this compilation, experimental neural tube defects have been formed and immunohistochemistry and immunofluorescent studies of some stem cells that are thought to have role in the formation of defect are compiled. From this point of view, it is aimed to determine the distributions of neural tube in rhe processes of normal development and defect formation, to understand the reproduction and alteration mechanisms of stem cells, and concomitantly to reveal the defect pathogenesis.
Anahtar Kelimeler
Ayrıntılar
Birincil Dil
İngilizce
Konular
Sağlık Kurumları Yönetimi
Bölüm
-
Yazarlar
Zeynep Deniz Şahin İnan
Serpil Ünver Saraydın
Yayımlanma Tarihi
25 Kasım 2016
Gönderilme Tarihi
17 Kasım 2016
Kabul Tarihi
-
Yayımlandığı Sayı
Yıl 2016 Cilt: 38 Sayı: 4