Acute necrotizing encephalopathy as a H1N1 complication: A rare case
Abstract
Abstract: Acute necrotizing
encephalopathy of childhood (ANEC) is a rare type of encephalopathy seen
generally in previously healthy children or infants of East Asian population.
The pathology generally considered to be triggered by infectious diseases,
mainly by viral agents. In this case report a previously healthy, 2-year –old,
male children diagnosed as ANEC, occuring secondarily to H1N1 infection is
presented. On MR images hyperintensity is present at bilateral thalamus and
brainstem on T2WI and FLAIR. On gradient echo sequences, hemorrage is also
present at bilateral thalamic region. ANEC does not have a specific symptomor
typical neurological sign. It is important to remember that the typical lesions
are generally seen in the gray matter of bilateral thalami. It is reported that
administration of steroids within first 24 hours just after ANEC diagnosis was
related to a better prognosis in patients without brain stem involvement. Early
diagnosis mostly depends on knowing the imaging characteristics of ANEC and
being aware of this rare entitiy.
Keywords
Kaynakça
- 1. Salehiomran MR, Nooreddini H, Baghdadi F. Acute necrotizing encephalopathy of childhood; a case report. Iran J Child Neurol. 2013;7(2):51-4.
- 2. Wu X, Wu W, Pan W, Wu L, Liu K, Zhang HL. Acute necrotizing encephalopathy: an underrecognized clinicoradiologic disorder. Mediators Inflamm. 2015;2015:792578.
- 3. Yoganathan S, Sudhakar SV, James EJ, Thomas MM. Acute necrotising encephalopathy in a child with H1N1 influenza infection: a clinicoradiological diagnosis and follow-up. BMJ Case Rep. 2016;2016.
- 4. Yadav S, Das CJ, Kumar V, Lodha R. Acute necrotizing encephalopathy. Indian J Pediatr. 2010;77(3):307-9.
- 5. Khan MR, Maheshwari PK, Ali SA, Anwarul H. Acute necrotizing encephalopathy of childhood: a fatal complication of swine flu. J Coll Physicians Surg Pak. 2011;21(2):119-20.
Ayrıntılar
Birincil Dil
İngilizce
Konular
Sağlık Kurumları Yönetimi
Bölüm
Olgu Sunumu
Yayımlanma Tarihi
18 Aralık 2017
Gönderilme Tarihi
21 Nisan 2017
Kabul Tarihi
4 Aralık 2017
Yayımlandığı Sayı
Yıl 2017 Cilt: 39 Sayı: 4