EN
Evaluation of cornea with specular microscopy in patients with ocular rozacea
Abstract
Objective: To investigate changes in corneal endothelial cell density, corneal morphology and central corneal thickness in patients with ocular rosacea.
Method: 60 eyes of 30 ocular rosacea patients and 60 eyes of 30 control group with similar demographic characteristics were included in the study. Detailed ophthalmological examination was performed in all individuals participating in the study. The eyes of all participants were evaluated by specular microscopy, schirmer 1 test, tear break-up time test (TBUT). Additionally, via specular microscopy the following parameters were assessed: endothelial cell density (ECD), mean cell area (ACA), minimum cell area (CAmin), maximum cell area (CA max), cell area standard deviation (SD), coefficient of variation in the cell area (CV), hexogonal cell ratio (HEX), central corneal thickness (CCT) numerical (NUM).
Results: Although none of the differences are statistically significant, patients with ocular rosacea have lower ACA, CA min, CA max, HEX, CCT and NUM values (p = 0,169, p = 0,897, p = 0,694, p = 0,649, p = 0,164 and p = 0,070, respectively), and higher CD, SD and CV values (p = 0.509, p = 0.437, p = 0.165, respectively). In ocular rosacea patients, there was no significant correlation was found the values of mean Schirmer test between CV, HEX, ECD, CT (p = 0.394, p = 0.906, p = 0.222, p = 0.208, respectively). Additionally, no significant correlation was found between tear break-up time and CV, HEX, ECD, CCT (p = 0.079, p = 0.227, p = 0.621, p = 0.712, respectively).
Conclusions: Our finding show that, despite the presence of some observable differences, corneal endothelial functions are similar to control group in patients with ocular rosacea.
Keywords
Destekleyen Kurum
Adıyaman University Faculty of Medicine
Proje Numarası
2017/8-2
Kaynakça
- 1 Wilkin J, Dahl M, Detmar M. Standard classification of rosacea: report of the national rosacea society expert committee on the classification and staging of rosacea. J Am Acad Dermatol 2002; 46:584–587.
Ayrıntılar
Birincil Dil
İngilizce
Konular
Sağlık Kurumları Yönetimi
Bölüm
Araştırma Makalesi
Yayımlanma Tarihi
31 Mart 2021
Gönderilme Tarihi
19 Kasım 2020
Kabul Tarihi
29 Mart 2021
Yayımlandığı Sayı
Yıl 2021 Cilt: 43 Sayı: 1