Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery

Ahmet Çora; Ersin Çelik; Kadir Burhan Karadem

doi:10.7197/cmj.937489

EN

Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery

Öz

Objective: Atrial fibrillation (AF) is the most common cardiac arrhythmia seen after coronary artery bypass(CABG) surgery. Hemoglobin A1c (HbA1c) levels known to have correlation with the developement of post operative atrial fibrillation (POAF) after CABG surgery. In our study we investigated the predictability of preoperative HbA1c levels for postoperative POAF developement in patients who underwent isolated on-pump CABG operation in our clinic.
Method: We retrospectiveley studied 85 isolated on-pump CABG patients. Male to female ratio was 3:1 and mean age was 63-year old. All patients monitored in intensive care unit and than service for the occurance of AF. Relationship between HbA1c levels and developement of AF after surgery was evaluated.
Results: This study designed as cross-sectional array and performed in our clinic. 85 patients included in the study. Mean age of cohort was 63.5 years and ratio of the male to female found 3:1. During postoperative monitoring period, 22 patients (25.8%) developed POAF (p>0.05) . HbA1c levels found significiantly high in POAF- positive group (p=0.003).
Conclusions: According to our data, preoperative HbA1c levels could be used as a predictor of post operative AF in patients undergoing CABG surgery.

Anahtar Kelimeler

Destekleyen Kurum

yok

Kaynakça

1- Jongnarangsin K, Oral H. Postoperative atrial fibrillation. Cardiology Clinics 2009;27(1):69-78
2- Mathew JP, Fontes ML, Tudor IC, Ramsay J, Dude P, Mazer CD, et al. A multicenter risk index for atrial fibrillation after cardiac surgery. JAMA 2004;291(14):1720-9
3- Quader MA, McCarthy PM, Gillinov AM, Alster JM, Cosgrove DM, Lytle BW, et al. Does preoperative atrial fibrillation reduce survival after coronary artery bypass grafting? The Annals of Thoracic Surgery 2004;77(5):1514-24.
4- Akyürek Ö, Diker E, Güldal M, Oral D. Predictive value of heart rate variability for the recurrence of chronic atrial fibrillation after electrical cardioversion. Clinical Cardiology 2003;26(4):196-200.
5- Guo Y, Hu S, Wu Q, Xu J, Song Y, Zhu X. Predictors of atrial fibrillation after coronary artery bypass graft surgery. Chin Med J (Engl) 2002;115(2):232‐4.
6- Mathew JP, Parks R, Savino JS , Friedman AS, Koch C, Mangano DT et al. Atrial fibrillation following Coronary Artery Bypass Graft Surgery. JAMA 1996; 276.21: 1719-20.
7- El-Chami, MF, Kilgo P, Thourani V, Lattouf OM, Delurgio DB, Guyton RA, et al. New-onset atrial fibrillation predicts long-term mortality after coronary artery bypass graft. Journal of the American College of Cardiology 2010; 55(13), 1370-6.
8- Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, Williams BA, et al. Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patients. Mayo Clinic Proceedings 2005; 80.7: 862-6.

9- Filardo G, Hamilton C, Hamman B, Hebeler RF, Grayburn PA. Relation of obesity to atrial fibrillation after isolated coronary artery bypass grafting. The American Journal of Cardiology. 2009;103(5):663-6.
10- Maisel WH, Rawn JD, Stevenson WG. Atrial fibrillation after cardiac surgery. Annals of Internal Medicine 2001; 135.12: 1061-73.
11- Leibowitz G, Raizman E, Mayer B, Glaser B, Raz I., Shapira O. Effects of moderate intensity glycemic control after cardiac surgery. The Annals of Thoracic Surgery 2010; 90(6), 1825-32.
12- Mont L, Tamborero D, Elosua R, Molina I, Coll-Vinent B, Sitges M et al. Physical activity, height, and left atrial size are independent risk factors for lone atrial fibrillation in middle-aged healthy individuals. Europace 2008; 10(1), 15-20.
13- Taylor AD, Groen JG, Thorn SL, Lewis CT, Marshall AJ. New insights into onset mechanisms of atrial fibrillation and flutter after coronary artery bypass graft surgery. Heart 2002; 88(5), 499-504.
14- Nardi F, Diena M, Caimmi P P, Iraghi G, Lazzero M, Cerin G et al. Relationship between left atrial volume and atrial fibrillation following coronary artery bypass grafting. Journal of Cardiac Surgery 2012; 27(1),128-35.
15- Kaw R, Hernandez, AV, Masood I, Gillinov AM, Saliba W, Blackstone EH. Short and long term mortality associated with new onset atrial fibrillation after coronary artery bypass grafting: a systematic review and meta-analysis. The Journal of Thoracic and Cardiovascular Surgery 2011; 141(5), 1305-12.
16- Crystal E, Connolly SJ., Sleik K , Ginger T J, Yusuf S. Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis. Circulation 2002; 106(1), 75-80.
17- Filardo G, Hamilton C, HebelerJr RF., Hamman B, Grayburn P. New-onset postoperative atrial fibrillation after isolated coronary artery bypass graft surgery and long-term survival. Circulation: Cardiovascular Quality and Outcomes 2009; 2(3), 164-9.
18- Elley C R, Kenealy T, Robinson E, Drury PL. Glycated haemoglobin and cardiovascular outcomes in people with Type 2 diabetes: a large prospective cohort study. Diabetic Medicine 2008; 25(11), 1295-1301.
19- Gillett MJ. International Expert Committee report on the role of the A1c assay in the diagnosis of diabetes: Diabetes Care. Clin Biochem Rev 2009; 30(4):197‐200.
20- Sacks DB, Arnold M, Bakris GL, Bruns DE., Horvath AR., Kirkman MS et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Diabetes Care 2011;34(6):61‐99.
21- Ramadan, Mona, et al. "Impact of elevated glycosylated hemoglobin on hospital outcome and 1 year survival of primary isolated coronary artery bypass grafting patients." The Egyptian Heart Journal 70.2 (2018): 113-8.
22- Yang Y F, Zhu W Q, Cheng K, Chen Q X, Xu Y, Pang Y et al. Elevated glycated hemoglobin levels may increase the risk of atrial fibrillation in patients with diabetes mellitus. International Journal of Clinical and Experimental Medicine 2015; 8(3), 3271.
23- Iguchi Y, Kimura K, Shibazaki K, Aoki J, Sakai K, Sakamoto Y. et al. HbA1c and atrial fibrillation: a cross-sectional study in Japan. International Journal of Cardiology 2012; 156(2), 156-9.
24- Rasoul S, Ottervanger J P, Bilo HJ, Timmer JR, van’tHof AWJ, Dambrink JHE et al. Glucose dysregulation in nondiabetic patients with ST-elevation myocardial infarction: acute and chronic glucose dysregulation in STEMI. Neth J Med 2007; 65(3), 95-100.
25- Ighodaro OM. "Molecular pathways associated with oxidative stress in diabetes mellitus." Biomedicine & Pharmacotherapy 108 (2018): 656-62.
26- Liu T, Li G, Li L, Korantzopoulos P. Association between C-reactive protein and recurrence of atrial fibrillation after successful electrical cardioversion: a meta-analysis. Journal of the American College of Cardiology 2007; 49(15), 1642-8.
27- Wong RK, Pettit AI, Quinn PA, Jennings SC, Davies JE, Ng LN. Advanced glycation end products stimulate an enhanced neutrophil respiratory burst mediated through the activation of cytosolic phospholipase A2 and generation of arachidonic acid. Circulation 2003; 108(15), 1858-64.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Ahmet Çora ^*
0000-0002-4892-9463
Türkiye

Ersin Çelik
0000-0002-0015-3280
Türkiye

Kadir Burhan Karadem
0000-0003-2410-8318
Türkiye

Yayımlanma Tarihi

30 Mart 2022

Gönderilme Tarihi

15 Mayıs 2021

Kabul Tarihi

22 Kasım 2021

Yayımlandığı Sayı

Yıl 2022 Cilt: 44 Sayı: 1

DOI

https://doi.org/10.7197/cmj.937489

IZ

https://izlik.org/JA59HP89MA

Kaynak Göster

RIS / Bibtex

APA

Çora, A., Çelik, E., & Karadem, K. B. (2022). Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery. Cumhuriyet Medical Journal, 44(1), 137-143. https://doi.org/10.7197/cmj.937489

AMA

1.Çora A, Çelik E, Karadem KB. Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery. CMJ. 2022;44(1):137-143. doi:10.7197/cmj.937489

Chicago

Çora, Ahmet, Ersin Çelik, ve Kadir Burhan Karadem. 2022. “Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery”. Cumhuriyet Medical Journal 44 (1): 137-43. https://doi.org/10.7197/cmj.937489.

EndNote

Çora A, Çelik E, Karadem KB (01 Mart 2022) Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery. Cumhuriyet Medical Journal 44 1 137–143.

IEEE

[1]A. Çora, E. Çelik, ve K. B. Karadem, “Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery”, CMJ, c. 44, sy 1, ss. 137–143, Mar. 2022, doi: 10.7197/cmj.937489.

ISNAD

Çora, Ahmet - Çelik, Ersin - Karadem, Kadir Burhan. “Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery”. Cumhuriyet Medical Journal 44/1 (01 Mart 2022): 137-143. https://doi.org/10.7197/cmj.937489.

JAMA

1.Çora A, Çelik E, Karadem KB. Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery. CMJ. 2022;44:137–143.

MLA

Çora, Ahmet, vd. “Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery”. Cumhuriyet Medical Journal, c. 44, sy 1, Mart 2022, ss. 137-43, doi:10.7197/cmj.937489.

Vancouver

1.Ahmet Çora, Ersin Çelik, Kadir Burhan Karadem. Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery. CMJ. 01 Mart 2022;44(1):137-43. doi:10.7197/cmj.937489