Öz
Primary
anal malignant melanoma is a rare tumor of the anal region. Usually it was
misdiagnosed as hemorrhoids or anal polyp so delayed diagnosis can lead
complicated status of the disease.Clinical and histopathological diagnosis may
be difficult due to uncommon presentation and smilar morphological findings
when compared with other malignant anal tumors. Effectiveness of the
chemotherapy and radiotheraphy are limited. Surgical resection is still seen as
standart treatment option and abdominoperineal resection (APR) and wide local
excision are the most preferred methods. In this paper we presented 55 year-old
male patient with recurrent anal malignant melanoma treated with
abdominoperineal resection.
Kaynakça
- 1. Thibault C, Sagar P, Nivatvongs S, et al. Anorectal melanoma -an incurable disease? Dis Colon Rectum 1997; 40: 661- 8.
- 2. Weinstock MA. Epidemiology and prognosis of anorectal melanoma. Gastroenterology 1993; 104: 174-8.
- 3. Bulus H, et al. Anorektumun Primer Malign Melanomu: Olgu Sunumu. Ulusal Cerrahi Dergisi 2011; 27: 240-2.
- 4. Sakız D, et al. Anorektal Malign Melanom: Üç Olgu sunumu. Türk Patoloji Dergisi 2006; 22: 37-41.
- 5. Dag A, et al. Anorectal Malign Melanoma: Retrospective Analysis of Surgical Outcomes of 8 Patients. Kolon Rektum Hast Derg 2013; 23: 31-7.
- 6. Belli F, Gallino GF, Lo Vullo S, et al. Melanoma of the anorectal region: the experience of the National Cancer Institute of Milano. Eur J Surg Oncol 2009; 35: 757-62.
- 7. Iddings DM, Fleisig AJ, Chen SL, et al. Practice patterns and outcomes for anorectal melanoma in the USA, reviewing three decades of treatment: is more extensive surgical resection beneficial in all patients? Ann Surg Oncol 2010; 17: 40-4.
- 8. Malik A, Hull T, Floruta C. What is the best surgical treatment for anorectal melanoma? Int J Colorectal Dis 2004; 19: 121-3.
- 9. Yeh JJ, Shia J, Hwu WJ, et al. The role of abdominoperineal resection as surgical therapy for anorectal melanoma. Annals Surg 2006; 244: 1012-7.
- 10. Van Schaik PM, Ernst MF, Meijer HA, Bosscha K. Melanoma of the rectum: A rare entity. World J Gastroenterol 2008; 14: 1633-5.
- 11. Tavusbay C, et al. Primary Malignant Melanoma of the Rectum: Analysis of Six Cases and Review of the Literature. Kolon Rektum Hast Derg 2011; 21: 109-15.
- 12. Pessaux P, Pocard M, Elias D, et al. Surgical management of primary anorectal melanoma. Brit J Surg 2004; 91: 1183-7.
- 13. Brady MS, Kavolius JP, Quan SH. Anorectal melanoma. A 64-year experience at Memorial SloanKettering Cancer Center. Dis Colon Rectum 1995; 38: 146-51.
- 14. Meguerditchian AN, Meterissian SH, Dunn KB. Anorectal melanoma: diagnosis and treatment. Dis Colon Rectum 2011; 54: 638-4.
- 15. Walls EW. Observations on the microscopic anatomy of the human anal canal. Br J Surg 1958; 45: 504-12.
- 16. Comstock G, Wynne E, Russell W. DOPA oxidase activity in differential diagnosis of amelanotic melanoma tissue. Cancer Res 1959; 19: 880-3.
- 17. Fitzpatrick TB. Human melanogenesis. Arch Dermatol 1952; 65: 379-91.
Öz
Primer anal malign melanom, anal bölgenin nadir görülen bir
patolojisidir. Genellikle anal melanomaya hemoroid ya da anal polip olarak
yanlış tanı konulmakta, bununla birlikte tanı ve tedavideki bu gecikme
hastalığın komplike bir tablo ile karşımıza çıkmasına neden olmaktadır.
Kemoterapi ve radyoterapinin yararlılığı sınırlıdır. Cerrahi standart tedavi
yöntemi olup abdominoperineal rezeksiyon (APR) veya genişletilmiş lokal
eksizyon en sık tercih edilen yöntemlerdir. Biz bu yazıda 55 yaşında APR ameliyatı yapılan nüks anorektal malign
melanomu olan erkek hastayı sunmayı amaçladık.
Kaynakça
- 1. Thibault C, Sagar P, Nivatvongs S, et al. Anorectal melanoma -an incurable disease? Dis Colon Rectum 1997; 40: 661- 8.
- 2. Weinstock MA. Epidemiology and prognosis of anorectal melanoma. Gastroenterology 1993; 104: 174-8.
- 3. Bulus H, et al. Anorektumun Primer Malign Melanomu: Olgu Sunumu. Ulusal Cerrahi Dergisi 2011; 27: 240-2.
- 4. Sakız D, et al. Anorektal Malign Melanom: Üç Olgu sunumu. Türk Patoloji Dergisi 2006; 22: 37-41.
- 5. Dag A, et al. Anorectal Malign Melanoma: Retrospective Analysis of Surgical Outcomes of 8 Patients. Kolon Rektum Hast Derg 2013; 23: 31-7.
- 6. Belli F, Gallino GF, Lo Vullo S, et al. Melanoma of the anorectal region: the experience of the National Cancer Institute of Milano. Eur J Surg Oncol 2009; 35: 757-62.
- 7. Iddings DM, Fleisig AJ, Chen SL, et al. Practice patterns and outcomes for anorectal melanoma in the USA, reviewing three decades of treatment: is more extensive surgical resection beneficial in all patients? Ann Surg Oncol 2010; 17: 40-4.
- 8. Malik A, Hull T, Floruta C. What is the best surgical treatment for anorectal melanoma? Int J Colorectal Dis 2004; 19: 121-3.
- 9. Yeh JJ, Shia J, Hwu WJ, et al. The role of abdominoperineal resection as surgical therapy for anorectal melanoma. Annals Surg 2006; 244: 1012-7.
- 10. Van Schaik PM, Ernst MF, Meijer HA, Bosscha K. Melanoma of the rectum: A rare entity. World J Gastroenterol 2008; 14: 1633-5.
- 11. Tavusbay C, et al. Primary Malignant Melanoma of the Rectum: Analysis of Six Cases and Review of the Literature. Kolon Rektum Hast Derg 2011; 21: 109-15.
- 12. Pessaux P, Pocard M, Elias D, et al. Surgical management of primary anorectal melanoma. Brit J Surg 2004; 91: 1183-7.
- 13. Brady MS, Kavolius JP, Quan SH. Anorectal melanoma. A 64-year experience at Memorial SloanKettering Cancer Center. Dis Colon Rectum 1995; 38: 146-51.
- 14. Meguerditchian AN, Meterissian SH, Dunn KB. Anorectal melanoma: diagnosis and treatment. Dis Colon Rectum 2011; 54: 638-4.
- 15. Walls EW. Observations on the microscopic anatomy of the human anal canal. Br J Surg 1958; 45: 504-12.
- 16. Comstock G, Wynne E, Russell W. DOPA oxidase activity in differential diagnosis of amelanotic melanoma tissue. Cancer Res 1959; 19: 880-3.
- 17. Fitzpatrick TB. Human melanogenesis. Arch Dermatol 1952; 65: 379-91.
Ayrıntılar
| Konular | Sağlık Kurumları Yönetimi |
|---|---|
| Bölüm | Case Reports |
| Yazarlar | |
| Yayımlanma Tarihi | 19 Eylül 2017 |
| Kabul Tarihi | 22 Mayıs 2017 |
| Yayımlandığı Sayı | Yıl 2017Cilt: 39 Sayı: 3 |