Objective:
In this study, we aimed to compare the healing effect of strontium ranilate(SR)
and hypericum perfaratum (HPE) with the healing effect of prednisolone used in
the treatment of experimental colit in rats.
Material
and Method: 30 wistar albino rats were used in the study. Rats
were randomly assigned to 5 consecutive groups consisting of 5 rats. Group 1,
healthy rats, group 2 colitis but untreated rats. The rats in groups 3, 4, and
5 had colitis and received 160 mg / kg SR, 1mg/kg prednisolone and HP extracts containing 0.3% hiperisine (250
uq / 300 mg) by oral gavage, respectively for seven days. At the end of the
seventh day, the colons of the rats were removed and histopathological
examination was performed.
Results:
The histopathological results of the HPE group were statistically worst
including the control group. It was observed that the best results in the
treatment groups were SR group followed by prednisolone group, respectively.(P<0.05)
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Cerrahi Tıp Bilimleri Araştırma Yazıları |
Yazarlar | |
Yayımlanma Tarihi | 28 Haziran 2018 |
Kabul Tarihi | 26 Haziran 2018 |
Yayımlandığı Sayı | Yıl 2018Cilt: 40 Sayı: 2 |