First and second trimester hCG levels have no value in predicting small for gestational age infants

Nilgün Güdücü; Gökçenur Gönenç; Herman İşçi; Alin Başgül Yiğiter; İlkkan Dünder

EN TR

First and second trimester hCG levels have no value in predicting small for gestational age infants

Abstract

Abstract

Aim. The aim of this study was to compare high hCG levels in the first and second trimester in predicting small-for-gestational age (SGA) infants. This is the first study that compares hCG levels of first and second trimesters. Methods. Patients with both first and second trimester Down syndrome screening tests were investigated retrospectively and human chorionic gonadotropin (hCG) values were recorded. Patients were divided into groups as SGA and non-SGA. High hCG values (≥2 MoM) were compared with low hCG values (<2MoM). Results. There was no significant difference in the hCG levels in women delivering SGA and non-SGA infants. Sensitivity and specificity of both tests were the same (9.09 and 89.95 respectively). Conclusions. Neither first nor second trimester hCG values were predictive in detection of SGA infants

Keywords: Small-for-gestational-age, hCG, Down syndrome screening tests

Özet

Amaç. Bu çalışmada amaç birinci ve ikinci trimester human chorionic gonadotropin (hCG) değerlerinin gebelik yaşına göre küçük bebekleri tahmin etmede faydalı olup olmadığını araştırmaktı. Yöntem. Hem birinci, hem de ikinci trimester Down sendromu tarama testi yaptırmış olan hastaların sonuçları retrospektif olarak tarandı ve hCG MoM değerleri tespit edildi. Hastalar gebelik yaşına göre küçük ve gebelik yaşına göre küçük (GYK) olan ve olmayan bebek doğuranlar olarak iki gruba ayrıldı. Yüksek hCG değerleri (≥2MoM) ile düşük hCG değerleri (<2MoM) karşılaştırıldı. Bulgular. GYK olan ve olmayan bebek doğuranların hCG değerleri arasında istatiksel olarak anlamlı bir fark görülmedi. Sensitivite ve spesifisite her iki grupta da aynı bulundu (sırasıyla 9.09 ve 89.95). Sonuç. Birinci ve ikinci trimester hCG değerlerinin GYK bebekleri tahmin etmede yeri yoktur.

Anahtar sözcükler: Gebelik yaşına göre küçük, hCG, Down sendromu tarama testleri

Keywords

Small-for-gestational-age, hCG, Down syndrome screening tests

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Nilgün Güdücü

Gökçenur Gönenç

Herman İşçi

Alin Başgül Yiğiter

İlkkan Dünder

Yayımlanma Tarihi

31 Ocak 2013

Gönderilme Tarihi

31 Ocak 2013

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 1970 Cilt: 35 Sayı: 2

IZ

https://izlik.org/JA48FX55XU

Kaynak Göster

RIS / Bibtex

AMA

1.Güdücü N, Gönenç G, İşçi H, Başgül Yiğiter A, Dünder İ. First and second trimester hCG levels have no value in predicting small for gestational age infants. CMJ. 2013;35(2):215-220. https://izlik.org/JA48FX55XU

Original research-Orijinal araştırma

First and second trimester hCG levels have no value in predicting small for gestational age infants

Abstract

Keywords

Original research-Orijinal araştırma

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

IZ

Kaynak Göster