Objective:
Prediabetes; is the first stage of
diabetes. It is a high-risk status for the development of diabetes mellitus
type 2, which is an important public health problem. Myocardial performance
index (MPI) is a noninvasive method that can be measured by echocardiography
showing left ventricular (LV) systolic and diastolic functions. In this study,
we aimed to investigate the relationship between prediabetes and MPI.
Method: Fifty-three consecutive patients without
chronic illness who were diagnosed with prediabetes and 48 otherwise healthy
subjects were enrolled in the study. Fasting blood glucose and HbA1c levels were measured from venous
blood samples. MPI values were
calculated by tissue Doppler imaging technique for all participants.
Results: In the prediabetic group,
the mean fasting blood glucose level was 115 ± 4 mg/dL, whereas in the control
group it was 90 ± 5 mg/dL.
As expected, HbA1c was statistically significantly higher in the patient group.
(% 5,7 ± 0,3 vs % 5,1±0,3, respectively). The MPI
values in the patient group were higher than the control group and this
difference was statistically significant (0.74 ± 0.12 vs. 0.64 ± 0.09;
p<0,001). There
were no statistically significant differences between the groups in terms of
age, gender, and body mass index.
Conclusions: In
prediabetic patients, MPI was higher than the control group, which may be
related to impaired LV systolic and diastolic functions.
Prediabetes Myocardial Performance Index Tissue Doppler Imaging
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Medical Science Research Makaleler |
Yazarlar | |
Yayımlanma Tarihi | 30 Haziran 2019 |
Kabul Tarihi | 27 Haziran 2019 |
Yayımlandığı Sayı | Yıl 2019Cilt: 41 Sayı: 2 |