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Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery

Yıl 2022, Cilt 44, Sayı 1, 137 - 143, 30.03.2022
https://doi.org/10.7197/cmj.937489

Öz

Objective: Atrial fibrillation (AF) is the most common cardiac arrhythmia seen after coronary artery bypass(CABG) surgery. Hemoglobin A1c (HbA1c) levels known to have correlation with the developement of post operative atrial fibrillation (POAF) after CABG surgery. In our study we investigated the predictability of preoperative HbA1c levels for postoperative POAF developement in patients who underwent isolated on-pump CABG operation in our clinic.
Method: We retrospectiveley studied 85 isolated on-pump CABG patients. Male to female ratio was 3:1 and mean age was 63-year old. All patients monitored in intensive care unit and than service for the occurance of AF. Relationship between HbA1c levels and developement of AF after surgery was evaluated.
Results: This study designed as cross-sectional array and performed in our clinic. 85 patients included in the study. Mean age of cohort was 63.5 years and ratio of the male to female found 3:1. During postoperative monitoring period, 22 patients (25.8%) developed POAF (p>0.05) . HbA1c levels found significiantly high in POAF- positive group (p=0.003).
Conclusions: According to our data, preoperative HbA1c levels could be used as a predictor of post operative AF in patients undergoing CABG surgery.

Kaynakça

  • 1- Jongnarangsin K, Oral H. Postoperative atrial fibrillation. Cardiology Clinics 2009;27(1):69-78
  • 2- Mathew JP, Fontes ML, Tudor IC, Ramsay J, Dude P, Mazer CD, et al. A multicenter risk index for atrial fibrillation after cardiac surgery. JAMA 2004;291(14):1720-9
  • 3- Quader MA, McCarthy PM, Gillinov AM, Alster JM, Cosgrove DM, Lytle BW, et al. Does preoperative atrial fibrillation reduce survival after coronary artery bypass grafting? The Annals of Thoracic Surgery 2004;77(5):1514-24.
  • 4- Akyürek Ö, Diker E, Güldal M, Oral D. Predictive value of heart rate variability for the recurrence of chronic atrial fibrillation after electrical cardioversion. Clinical Cardiology 2003;26(4):196-200.
  • 5- Guo Y, Hu S, Wu Q, Xu J, Song Y, Zhu X. Predictors of atrial fibrillation after coronary artery bypass graft surgery. Chin Med J (Engl) 2002;115(2):232‐4.
  • 6- Mathew JP, Parks R, Savino JS , Friedman AS, Koch C, Mangano DT et al. Atrial fibrillation following Coronary Artery Bypass Graft Surgery. JAMA 1996; 276.21: 1719-20.
  • 7- El-Chami, MF, Kilgo P, Thourani V, Lattouf OM, Delurgio DB, Guyton RA, et al. New-onset atrial fibrillation predicts long-term mortality after coronary artery bypass graft. Journal of the American College of Cardiology 2010; 55(13), 1370-6.
  • 8- Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, Williams BA, et al. Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patients. Mayo Clinic Proceedings 2005; 80.7: 862-6.
  • 9- Filardo G, Hamilton C, Hamman B, Hebeler RF, Grayburn PA. Relation of obesity to atrial fibrillation after isolated coronary artery bypass grafting. The American Journal of Cardiology. 2009;103(5):663-6.
  • 10- Maisel WH, Rawn JD, Stevenson WG. Atrial fibrillation after cardiac surgery. Annals of Internal Medicine 2001; 135.12: 1061-73.
  • 11- Leibowitz G, Raizman E, Mayer B, Glaser B, Raz I., Shapira O. Effects of moderate intensity glycemic control after cardiac surgery. The Annals of Thoracic Surgery 2010; 90(6), 1825-32.
  • 12- Mont L, Tamborero D, Elosua R, Molina I, Coll-Vinent B, Sitges M et al. Physical activity, height, and left atrial size are independent risk factors for lone atrial fibrillation in middle-aged healthy individuals. Europace 2008; 10(1), 15-20.
  • 13- Taylor AD, Groen JG, Thorn SL, Lewis CT, Marshall AJ. New insights into onset mechanisms of atrial fibrillation and flutter after coronary artery bypass graft surgery. Heart 2002; 88(5), 499-504.
  • 14- Nardi F, Diena M, Caimmi P P, Iraghi G, Lazzero M, Cerin G et al. Relationship between left atrial volume and atrial fibrillation following coronary artery bypass grafting. Journal of Cardiac Surgery 2012; 27(1),128-35.
  • 15- Kaw R, Hernandez, AV, Masood I, Gillinov AM, Saliba W, Blackstone EH. Short and long term mortality associated with new onset atrial fibrillation after coronary artery bypass grafting: a systematic review and meta-analysis. The Journal of Thoracic and Cardiovascular Surgery 2011; 141(5), 1305-12.
  • 16- Crystal E, Connolly SJ., Sleik K , Ginger T J, Yusuf S. Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis. Circulation 2002; 106(1), 75-80.
  • 17- Filardo G, Hamilton C, HebelerJr RF., Hamman B, Grayburn P. New-onset postoperative atrial fibrillation after isolated coronary artery bypass graft surgery and long-term survival. Circulation: Cardiovascular Quality and Outcomes 2009; 2(3), 164-9.
  • 18- Elley C R, Kenealy T, Robinson E, Drury PL. Glycated haemoglobin and cardiovascular outcomes in people with Type 2 diabetes: a large prospective cohort study. Diabetic Medicine 2008; 25(11), 1295-1301.
  • 19- Gillett MJ. International Expert Committee report on the role of the A1c assay in the diagnosis of diabetes: Diabetes Care. Clin Biochem Rev 2009; 30(4):197‐200.
  • 20- Sacks DB, Arnold M, Bakris GL, Bruns DE., Horvath AR., Kirkman MS et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Diabetes Care 2011;34(6):61‐99.
  • 21- Ramadan, Mona, et al. "Impact of elevated glycosylated hemoglobin on hospital outcome and 1 year survival of primary isolated coronary artery bypass grafting patients." The Egyptian Heart Journal 70.2 (2018): 113-8.
  • 22- Yang Y F, Zhu W Q, Cheng K, Chen Q X, Xu Y, Pang Y et al. Elevated glycated hemoglobin levels may increase the risk of atrial fibrillation in patients with diabetes mellitus. International Journal of Clinical and Experimental Medicine 2015; 8(3), 3271.
  • 23- Iguchi Y, Kimura K, Shibazaki K, Aoki J, Sakai K, Sakamoto Y. et al. HbA1c and atrial fibrillation: a cross-sectional study in Japan. International Journal of Cardiology 2012; 156(2), 156-9.
  • 24- Rasoul S, Ottervanger J P, Bilo HJ, Timmer JR, van’tHof AWJ, Dambrink JHE et al. Glucose dysregulation in nondiabetic patients with ST-elevation myocardial infarction: acute and chronic glucose dysregulation in STEMI. Neth J Med 2007; 65(3), 95-100.
  • 25- Ighodaro OM. "Molecular pathways associated with oxidative stress in diabetes mellitus." Biomedicine & Pharmacotherapy 108 (2018): 656-62.
  • 26- Liu T, Li G, Li L, Korantzopoulos P. Association between C-reactive protein and recurrence of atrial fibrillation after successful electrical cardioversion: a meta-analysis. Journal of the American College of Cardiology 2007; 49(15), 1642-8.
  • 27- Wong RK, Pettit AI, Quinn PA, Jennings SC, Davies JE, Ng LN. Advanced glycation end products stimulate an enhanced neutrophil respiratory burst mediated through the activation of cytosolic phospholipase A2 and generation of arachidonic acid. Circulation 2003; 108(15), 1858-64.

Yıl 2022, Cilt 44, Sayı 1, 137 - 143, 30.03.2022
https://doi.org/10.7197/cmj.937489

Öz

Kaynakça

  • 1- Jongnarangsin K, Oral H. Postoperative atrial fibrillation. Cardiology Clinics 2009;27(1):69-78
  • 2- Mathew JP, Fontes ML, Tudor IC, Ramsay J, Dude P, Mazer CD, et al. A multicenter risk index for atrial fibrillation after cardiac surgery. JAMA 2004;291(14):1720-9
  • 3- Quader MA, McCarthy PM, Gillinov AM, Alster JM, Cosgrove DM, Lytle BW, et al. Does preoperative atrial fibrillation reduce survival after coronary artery bypass grafting? The Annals of Thoracic Surgery 2004;77(5):1514-24.
  • 4- Akyürek Ö, Diker E, Güldal M, Oral D. Predictive value of heart rate variability for the recurrence of chronic atrial fibrillation after electrical cardioversion. Clinical Cardiology 2003;26(4):196-200.
  • 5- Guo Y, Hu S, Wu Q, Xu J, Song Y, Zhu X. Predictors of atrial fibrillation after coronary artery bypass graft surgery. Chin Med J (Engl) 2002;115(2):232‐4.
  • 6- Mathew JP, Parks R, Savino JS , Friedman AS, Koch C, Mangano DT et al. Atrial fibrillation following Coronary Artery Bypass Graft Surgery. JAMA 1996; 276.21: 1719-20.
  • 7- El-Chami, MF, Kilgo P, Thourani V, Lattouf OM, Delurgio DB, Guyton RA, et al. New-onset atrial fibrillation predicts long-term mortality after coronary artery bypass graft. Journal of the American College of Cardiology 2010; 55(13), 1370-6.
  • 8- Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, Williams BA, et al. Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patients. Mayo Clinic Proceedings 2005; 80.7: 862-6.
  • 9- Filardo G, Hamilton C, Hamman B, Hebeler RF, Grayburn PA. Relation of obesity to atrial fibrillation after isolated coronary artery bypass grafting. The American Journal of Cardiology. 2009;103(5):663-6.
  • 10- Maisel WH, Rawn JD, Stevenson WG. Atrial fibrillation after cardiac surgery. Annals of Internal Medicine 2001; 135.12: 1061-73.
  • 11- Leibowitz G, Raizman E, Mayer B, Glaser B, Raz I., Shapira O. Effects of moderate intensity glycemic control after cardiac surgery. The Annals of Thoracic Surgery 2010; 90(6), 1825-32.
  • 12- Mont L, Tamborero D, Elosua R, Molina I, Coll-Vinent B, Sitges M et al. Physical activity, height, and left atrial size are independent risk factors for lone atrial fibrillation in middle-aged healthy individuals. Europace 2008; 10(1), 15-20.
  • 13- Taylor AD, Groen JG, Thorn SL, Lewis CT, Marshall AJ. New insights into onset mechanisms of atrial fibrillation and flutter after coronary artery bypass graft surgery. Heart 2002; 88(5), 499-504.
  • 14- Nardi F, Diena M, Caimmi P P, Iraghi G, Lazzero M, Cerin G et al. Relationship between left atrial volume and atrial fibrillation following coronary artery bypass grafting. Journal of Cardiac Surgery 2012; 27(1),128-35.
  • 15- Kaw R, Hernandez, AV, Masood I, Gillinov AM, Saliba W, Blackstone EH. Short and long term mortality associated with new onset atrial fibrillation after coronary artery bypass grafting: a systematic review and meta-analysis. The Journal of Thoracic and Cardiovascular Surgery 2011; 141(5), 1305-12.
  • 16- Crystal E, Connolly SJ., Sleik K , Ginger T J, Yusuf S. Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis. Circulation 2002; 106(1), 75-80.
  • 17- Filardo G, Hamilton C, HebelerJr RF., Hamman B, Grayburn P. New-onset postoperative atrial fibrillation after isolated coronary artery bypass graft surgery and long-term survival. Circulation: Cardiovascular Quality and Outcomes 2009; 2(3), 164-9.
  • 18- Elley C R, Kenealy T, Robinson E, Drury PL. Glycated haemoglobin and cardiovascular outcomes in people with Type 2 diabetes: a large prospective cohort study. Diabetic Medicine 2008; 25(11), 1295-1301.
  • 19- Gillett MJ. International Expert Committee report on the role of the A1c assay in the diagnosis of diabetes: Diabetes Care. Clin Biochem Rev 2009; 30(4):197‐200.
  • 20- Sacks DB, Arnold M, Bakris GL, Bruns DE., Horvath AR., Kirkman MS et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Diabetes Care 2011;34(6):61‐99.
  • 21- Ramadan, Mona, et al. "Impact of elevated glycosylated hemoglobin on hospital outcome and 1 year survival of primary isolated coronary artery bypass grafting patients." The Egyptian Heart Journal 70.2 (2018): 113-8.
  • 22- Yang Y F, Zhu W Q, Cheng K, Chen Q X, Xu Y, Pang Y et al. Elevated glycated hemoglobin levels may increase the risk of atrial fibrillation in patients with diabetes mellitus. International Journal of Clinical and Experimental Medicine 2015; 8(3), 3271.
  • 23- Iguchi Y, Kimura K, Shibazaki K, Aoki J, Sakai K, Sakamoto Y. et al. HbA1c and atrial fibrillation: a cross-sectional study in Japan. International Journal of Cardiology 2012; 156(2), 156-9.
  • 24- Rasoul S, Ottervanger J P, Bilo HJ, Timmer JR, van’tHof AWJ, Dambrink JHE et al. Glucose dysregulation in nondiabetic patients with ST-elevation myocardial infarction: acute and chronic glucose dysregulation in STEMI. Neth J Med 2007; 65(3), 95-100.
  • 25- Ighodaro OM. "Molecular pathways associated with oxidative stress in diabetes mellitus." Biomedicine & Pharmacotherapy 108 (2018): 656-62.
  • 26- Liu T, Li G, Li L, Korantzopoulos P. Association between C-reactive protein and recurrence of atrial fibrillation after successful electrical cardioversion: a meta-analysis. Journal of the American College of Cardiology 2007; 49(15), 1642-8.
  • 27- Wong RK, Pettit AI, Quinn PA, Jennings SC, Davies JE, Ng LN. Advanced glycation end products stimulate an enhanced neutrophil respiratory burst mediated through the activation of cytosolic phospholipase A2 and generation of arachidonic acid. Circulation 2003; 108(15), 1858-64.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Bilimleri ve Hizmetleri
Bölüm Editöre Mektuplar
Yazarlar

Ahmet ÇORA (Sorumlu Yazar)
ISPARTA ŞEHİR HASTANESİ
0000-0002-4892-9463
Türkiye


Ersin ÇELİK
ısparta şehir hastanesi
0000-0002-0015-3280
Türkiye


Kadir Burhan KARADEM
SULEYMAN DEMIREL UNIVERSITY, SCHOOL OF MEDICINE
0000-0003-2410-8318
Türkiye

Destekleyen Kurum yok
Yayımlanma Tarihi 30 Mart 2022
Yayınlandığı Sayı Yıl 2022, Cilt 44, Sayı 1

Kaynak Göster

APA Çora, A. , Çelik, E. & Karadem, K. B. (2022). Predictive role of preoperative hemoglobin A1c levels on atrial fibrillation developing after coronary artery bypass graft surgery . Cumhuriyet Medical Journal , 44 (1) , 137-143 . DOI: 10.7197/cmj.937489